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Conjugated Linoleic Acid

notesDescription

Conjugated Linoleic Acid (CLA) is a naturally occurring trans fatty acid, primarily found in the meat and dairy products of ruminant animals. It is a derivative of linoleic acid, an omega-6 fatty acid, but with a unique structure involving conjugated double bonds. This structural difference is believed to contribute to its distinct biological activities compared to other fatty acids. CLA gained significant attention for its potential health benefits, particularly in the areas of body composition and metabolic health. Research has explored its role in reducing body fat, increasing lean muscle mass, and modulating lipid metabolism. It is also studied for its anti-inflammatory and antioxidant properties, suggesting broader health implications beyond weight management. Available as a dietary supplement, CLA typically consists of a mixture of different CLA isomers, with cis-9, trans-11 (c9,t11) and trans-10, cis-12 (t10,c12) being the most common and biologically active. The specific effects of CLA can vary depending on the isomer composition and the dosage used in studies.

ecoSources
BeefLambDairy products (milk, cheese, yogurt)Eggs (to a lesser extent, depending on animal feed)
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check_circleOptimal Dosage
Minimum1000 mg
Maximum3000 mg
report_problemSafety & Toxicity
track_changesGoals
Immunity
health_and_safetyImmunity
Impact
Limited evidence
Typical dose:3.2–6.4 g
While some research suggests CLA can influence inflammatory markers in specific contexts, it lacks robust clinical evidence for general immune support or acute infection response. Its effects are not consistently demonstrated and are considered speculative for this purpose.
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Metabolism Boost
local_fire_departmentMetabolism Boost
Impact
Limited evidence
Typical dose:3.2–6.4 g
Human clinical trials on CLA have produced mixed results, with any observed effects on fat mass or metabolic rate being very modest and not reliably reproducible. Its classification should reflect the low probability of a meaningful outcome for the average user.
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Weight Loss
trending_downWeight Loss
Impact
Limited evidence
Typical dose:3.2–6.4 g
While animal studies show promise, human trials on CLA have produced mixed and often clinically insignificant results for fat loss. Any potential effects on inhibiting fat storage or increasing fat burning are typically very small and not reliably observed across the population.
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sync_altInteractions

add_circle_outlinePositive Interactions

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Omega-3
May synergistically support anti-inflammatory responses and overall metabolic health, as both are beneficial fatty acids.
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Omega-6
As a derivative of linoleic acid, CLA's metabolism is intrinsically linked with other omega-6 fatty acids, potentially contributing to a balanced fatty acid profile.
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L-Carnitine
May enhance fat metabolism and energy production, potentially complementing CLA's role in body composition by facilitating fatty acid transport.
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Chromium
May support healthy glucose and lipid metabolism, potentially complementing CLA's effects on body composition and mitigating potential impacts on insulin sensitivity.

remove_circle_outlineNegative Interactions

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Iron
Some animal studies suggest CLA might influence iron status; monitoring may be advised, especially with high doses.
analyticsProduct stats
sellPrice per product
Average$23.24
Median$20.06
restaurantPrice per serving
Average$0.46
Median$0.39
sciencePrice per 1000 mg
Average$0.45
Median$0.18
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bar_chartPrice per serving distribution
bar_chartPrice per 1000 mg
Reference amount: 1000 mg
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water_dropIngredient forms

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