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Glutathione

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Glutathione, often referred to as the 'master antioxidant', is a tripeptide molecule found in virtually every cell of the body. It is endogenously synthesized from the amino acids L-cysteine, L-glutamic acid, and glycine, and its primary function involves protecting the body from damage by reactive oxygen species, heavy metals, and various toxins. This makes it fundamental for maintaining cellular integrity and overall health. Beyond its direct antioxidant activity, glutathione is vital for numerous cellular processes including DNA synthesis and repair, protein synthesis, enzyme activation, and immune system function. It is particularly concentrated in the liver, where it assists in the detoxification of both endogenous and exogenous compounds, making it a cornerstone of the body's natural defense system against environmental pollutants and metabolic waste products. Maintaining adequate levels of glutathione is crucial for health, especially as levels can decline with age, poor nutrition, chronic stress, and exposure to toxins. Supplementation or supporting its natural production through precursors and cofactors is often pursued to bolster antioxidant defenses, support liver health, and enhance immune responses, contributing to cellular vitality and disease prevention.

ecoSources
AsparagusAvocadosSpinachBroccoliBrussels sproutsGarlicOnionsCabbageLean protein sources (for precursor amino acids)
Cheapest Glutathione supplements
Discover the most affordable Glutathione supplements designed to provide effective anti-inflammatory support, helping you find the best value for your health needs.
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Explore our top picks for glutathione supplements, carefully selected to help you find the best options for anti-inflammatory support.
Value Glutathione supplements
Compare top-rated Glutathione amino acid supplements to find the best value for anti-inflammatory support.
check_circleOptimal Dosage
Minimum250 mg
Maximum1000 mg
report_problemSafety & Toxicity
track_changesGoals
Anti-Inflammatory Support
local_hospitalAnti-Inflammatory Support
Impact
High effect
Typical dose:250–1000 mg
Glutathione is crucial for cellular defense against oxidative stress, a primary driver of chronic inflammation. Supplementing directly (with a bioavailable form) bolsters the body's ability to quench inflammatory fires, protecting cells from damage and supporting detoxification pathways.
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Cysteine
Cysteine is a crucial precursor amino acid for glutathione synthesis, directly enhancing the body's ability to produce glutathione.
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Glutamic Acid
Glutamic Acid is one of the three essential amino acids required for the body to synthesize glutathione.
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Glycine
Glycine is a foundational amino acid necessary for the endogenous production of glutathione.
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Vitamin C
Vitamin C helps regenerate oxidized glutathione back to its active form, extending its antioxidant capacity.
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Selenium
Selenium is a cofactor for the enzyme glutathione peroxidase, which uses glutathione to neutralize harmful peroxides.
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Milk Thistle
Milk Thistle (silymarin) is known to support liver health and may help increase hepatic glutathione levels.
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Vitamin E
Vitamin E and Glutathione work synergistically as antioxidants, where Vitamin E protects cell membranes and glutathione recycles Vitamin E, enhancing overall antioxidant defense.
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sellPrice per product
Average$34.63
Median$29.87
restaurantPrice per serving
Average$0.96
Median$0.54
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