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EPA (Eicosapentaenoic Acid)

notesDescription

EPA is a long-chain polyunsaturated omega-3 fatty acid, classified as essential because the human body cannot produce it and must acquire it through diet or supplementation. It serves as a precursor to eicosanoids, which are signaling molecules that regulate various physiological processes, including inflammation, blood clotting, and immune responses. Research consistently highlights EPA's significant benefits for cardiovascular health, including its ability to help maintain healthy triglyceride levels and support arterial function. Its profound anti-inflammatory properties make it beneficial for mitigating inflammation throughout the body, offering potential relief for conditions like arthritis and general inflammatory states. Beyond physical health, EPA plays a role in supporting brain health and mood regulation. It contributes to neuronal function and has been studied for its potential in helping to manage symptoms of depression and anxiety, often working in conjunction with DHA to promote overall cognitive well-being and mental clarity.

ecoSources
Fatty fish (e.g., salmon, mackerel, sardines, anchovies, herring, tuna)Algae (certain microalgae)Krill oil
Cheapest EPA (Eicosapentaenoic Acid) Supplements
Discover the cheapest EPA (Eicosapentaenoic Acid) fatty acid supplements available, supporting your goals for heart health, mental focus, cognitive support, and vision.
Best EPA supplements
Discover the best EPA (Eicosapentaenoic Acid) supplements to support your heart health, mental focus, cognitive function, and vision.
Value EPA (Eicosapentaenoic Acid) supplements
Explore value EPA (Eicosapentaenoic Acid) supplements to support heart health, mental focus, cognitive function, and vision.
check_circleOptimal Dosage
Minimum250 mg
Maximum1000 mg
report_problemSafety & Toxicity
Toxicity Threshold5000 mg
Toxicity EffectIncreased bleeding risk
track_changesGoals
Cognitive Support
psychology_altCognitive Support
Impact
Highest effect
Typical dose:250–1000 mg
While DHA is structural, EPA plays a vital role in regulating inflammation within the brain, which is a key factor in cognitive aging and mood disorders. It also helps produce signaling molecules that support overall brain function.
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Heart Health
favoriteHeart Health
Impact
Highest effect
Typical dose:1000–2000 mg
As a primary component of Omega-3, EPA directly competes with pro-inflammatory arachidonic acid, reducing the production of inflammatory eicosanoids. This reduction in systemic inflammation is crucial for preventing the progression of atherosclerosis.
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Vision Support
visibilityVision Support
Impact
High effect
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid that produces signaling molecules which potently reduce inflammation. This action is highly beneficial for ocular surface health, helping to alleviate symptoms of dry eye syndrome by reducing inflammation in the tear-producing glands. It works synergistically with DHA's structural role. The priority should be set to reflect its high efficacy.
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Mental Focus
center_focus_strongMental Focus
Impact
Moderate effect
While DHA is structural, EPA plays a significant role in reducing inflammatory processes in the brain. Elevated inflammation is linked to brain fog and cognitive fatigue. By supporting a healthy inflammatory response and mood, EPA helps create a better internal environment for sustained concentration.
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sync_altInteractions

add_circle_outlinePositive Interactions

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DHA
EPA and DHA are both crucial omega-3 fatty acids that synergistically support brain health, cardiovascular function, and anti-inflammatory processes, enhancing overall benefits.
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Omega-3
EPA is a primary component of Omega-3 supplements; taking them together ensures a balanced and comprehensive intake of essential fatty acids for overall health benefits.
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Vitamin E
Vitamin E, an antioxidant, helps protect EPA from oxidation, thereby maintaining its stability and efficacy in the body.
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Curcumin
Both EPA and Curcumin possess strong anti-inflammatory properties; their combined use may offer enhanced benefits in managing inflammatory conditions.
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Resveratrol
Resveratrol and EPA both support cardiovascular health and possess antioxidant properties, potentially offering synergistic benefits for heart protection and reducing oxidative stress.

remove_circle_outlineNegative Interactions

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Ginkgo
Both EPA and Ginkgo can have blood-thinning effects; combining them may increase the risk of bleeding or bruising.
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Ginger
Ginger has mild anti-platelet effects which, when combined with high doses of EPA, could theoretically increase the risk of bleeding.
inventory_2Recommended products
62 Value Omega-3 Fish Oil 1000 mg Lemon

Omega-3 Fish Oil 1000 mg Lemon

Natrol
4.8
★★★★★
(13310 ratings)
EPA (Eicosapentaenoic Acid): 180 mg
A highly economical lemon-flavored fish oil delivering 300mg of total omega-3s (EPA/DHA) per serving, suitable for broad daily health support.
Buy for $10.99(from iHerb)
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90 Best Max High Concentrate Omega-3 Fish Oil 2400 mg Citrus Burst

Max High Concentrate Omega-3 Fish Oil 2400 mg Citrus Burst

Coromega
4.8
★★★★★
(360 ratings)
EPA (Eicosapentaenoic Acid): 1250 mg
A highly potent, flavorful liquid Omega-3 squeeze shot, packed with EPA, DHA, Vitamin D3, and Vitamin C for comprehensive, convenient daily health support.
Buy for $48.96(from iHerb)
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98 Best Ultra Pure Fish Oil 2600 Lemon Flavor

Ultra Pure Fish Oil 2600 Lemon Flavor

Vital Nutrients
4.7
★★★★★
(3 ratings)
EPA (Eicosapentaenoic Acid): 2002 mg
This lemon-flavored liquid fish oil provides an exceptionally high dose of EPA and DHA per serving, making it a very potent option for comprehensive omega-3 support.
Buy for $94.99(from Pure Formulas)
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92 Best Omega 3 Mood

Omega 3 Mood

Country Life
4.7
★★★★★
(586 ratings)
EPA (Eicosapentaenoic Acid): 1000 mg
This Country Life Omega 3 supplement offers a high EPA dose, combined with some DHA and Vitamin E, for those seeking daily support for mood and general well-being.
Buy for $62.71(from Pure Formulas)
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98 Best Wild Alaskan Fish Oil Peak Omega-3 Liquid Natural Lemon Flavor

Wild Alaskan Fish Oil Peak Omega-3 Liquid Natural Lemon Flavor

Wiley's Finest
4.9
★★★★★
(1076 ratings)
EPA (Eicosapentaenoic Acid): 1300 mg
This liquid fish oil provides a very high dose of EPA and DHA in a natural lemon flavor, ideal for those seeking strong omega-3 support and preferring a non-capsule format.
Buy for $52.79(from Pure Formulas)
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90 Best Omega 3 Mood Natural Lemon Flavored

Omega 3 Mood Natural Lemon Flavored

Country Life
4.7
★★★★★
(399 ratings)
EPA (Eicosapentaenoic Acid): 1000 mg
This lemon-flavored Country Life Omega 3 supplement delivers a high EPA dose, alongside DHA and Vitamin E, supporting mood and general health with a more pleasant taste experience.
Buy for $34.71(from iHerb)
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95 Best Omega-3 2400 mg

Omega-3 2400 mg

Gaspari Nutrition
4.7
★★★★★
(102 ratings)
EPA (Eicosapentaenoic Acid): 960 mg
This softgel delivers a very high and balanced 960mg EPA and 720mg DHA per serving, making it a powerful option for broad omega-3 benefits.
Buy for $24.99(from iHerb)
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68 Budget Omega-3 Fish Oil with Vitamin D 1000 mg Lemon Flavored

Omega-3 Fish Oil with Vitamin D 1000 mg Lemon Flavored

Swanson
4.8
★★★★★
(1327 ratings)
EPA (Eicosapentaenoic Acid): 180 mg
An economical fish oil providing 300mg total omega-3s (EPA/DHA) plus Vitamin D3, with lemon flavoring for improved palatability, making it a good all-around daily supplement.
Buy for $6.19(from iHerb)
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62 Budget Fish Oil 1000 mg

Fish Oil 1000 mg

Mason Natural
4.7
★★★★★
(3591 ratings)
EPA (Eicosapentaenoic Acid): 180 mg
A budget-friendly fish oil offering 300mg of total omega-3s (EPA/DHA) per serving, suitable for basic daily supplementation.
Buy for $12.66(from iHerb)
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62 Budget Fish Oil 1000 mg

Fish Oil 1000 mg

Mason Natural
4.7
★★★★★
(3639 ratings)
EPA (Eicosapentaenoic Acid): 180 mg
A budget-friendly fish oil offering 300mg of total omega-3s (EPA/DHA) per serving, suitable for basic daily supplementation, available in a smaller count.
Buy for $7.01(from iHerb)
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Fish Oil 1250 mg

Evlution Nutrition
4.7
★★★★★
(666 ratings)
EPA (Eicosapentaenoic Acid): 450 mg
This fish oil supplement from Evlution Nutrition offers a robust 900 mg of omega-3s per softgel, with strong EPA and DHA content, all at a very affordable price point.
Buy for $9.99(from Bodybuilding Com)
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70 Value Fish Oil 1400 mg

Fish Oil 1400 mg

Nature's Bounty
4.7
★★★★★
(461 ratings)
EPA (Eicosapentaenoic Acid): 647 mg
An economical fish oil softgel providing a good EPA dose, suitable for budget-conscious users focused on general Omega-3 support.
Buy for $10.84(from iHerb)
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93 Best Alaska Wild Fish Oil Mega Omega-3

Alaska Wild Fish Oil Mega Omega-3

21st Century
4.8
★★★★★
(839 ratings)
EPA (Eicosapentaenoic Acid): 965 mg
This softgel provides a very high, EPA-dominant dose (965mg EPA, 385mg DHA), excellent for targeted heart health and anti-inflammatory support.
Buy for $13.24(from Pure Formulas)
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98 Best Omega-3

Omega-3

Solgar
4.8
★★★★★
(47797 ratings)
EPA (Eicosapentaenoic Acid): 1008 mg
This softgel offers an exceptionally high and balanced 1008mg EPA and 756mg DHA per serving, providing robust and comprehensive omega-3 support.
Buy for $29.59(from Vitacost)
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97 Best Super EPA Pro

Super EPA Pro

Thorne
4.9
★★★★★
(322 ratings)
EPA (Eicosapentaenoic Acid): 1300 mg
Thorne's Super EPA Pro provides an exceptionally high dose of EPA and DHA in gelcap form, offering potent support for heart, cognitive, and overall health from a respected brand.
Buy for $93(from iHerb)
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80 Budget Omega 3 Fish Oil Concentrate

Omega 3 Fish Oil Concentrate

Solgar
4.8
★★★★★
(24768 ratings)
EPA (Eicosapentaenoic Acid): 320 mg
This economical softgel provides a moderate 320mg EPA and 200mg DHA per serving, suitable for general daily omega-3 intake.
Buy for $11.99(from Vitacost)
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90 Best Max High Concentrate Omega-3 Fish Oil 2400 mg Coconut Bliss

Max High Concentrate Omega-3 Fish Oil 2400 mg Coconut Bliss

Coromega
4.7
★★★★★
(211 ratings)
EPA (Eicosapentaenoic Acid): 1250 mg
A very potent coconut-flavored liquid Omega-3 squeeze shot, rich in EPA, DHA, Vitamin D3, and Vitamin C, offering a delightful and comprehensive daily health solution.
Buy for $48.96(from iHerb)
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78 Value Purified & Clear Omega 3 Fish Oil 1000 mg

Purified & Clear Omega 3 Fish Oil 1000 mg

Doctor's Best
4.8
★★★★★
(4277 ratings)
EPA (Eicosapentaenoic Acid): 800 mg
A reliable fish oil in softgel form, offering a balanced and effective dose of EPA and DHA for general health and well-being.
Buy for $25.99(from iHerb)
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78 Budget Super Fisol Fish Oil

Super Fisol Fish Oil

Nature's Way
4.6
★★★★★
(353 ratings)
EPA (Eicosapentaenoic Acid): 200 mg
A highly concentrated fish oil delivering 350mg of EPA and DHA from a 500mg softgel, ideal for efficient and potent omega-3 supplementation.
Buy for $34.52(from Pure Formulas)
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88 Value Omega-3 Triglyceride Fish Oil 1100 mg

Omega-3 Triglyceride Fish Oil 1100 mg

NATURELO Premium Supplements
4.8
★★★★★
(2746 ratings)
EPA (Eicosapentaenoic Acid): 729 mg
An excellent value, high-potency triglyceride fish oil with strong EPA, delivered in a convenient single softgel for long-term, superior Omega-3 support.
Buy for $44.95(from Pure Formulas)
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88 Value Mega EPA/DHA

Mega EPA/DHA

Life Extension
4.8
★★★★★
(10259 ratings)
EPA (Eicosapentaenoic Acid): 720 mg
This softgel provides a solid 720mg EPA and 480mg DHA per serving, with added Vitamin E, supporting broad omega-3 health benefits.
Buy for $20.25(from iHerb)
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58 Budget Wild Alaskan Salmon Oil 1000 mg

Wild Alaskan Salmon Oil 1000 mg

Natural Factors OmegaFactors
4.8
★★★★★
(6190 ratings)
EPA (Eicosapentaenoic Acid): 80 mg
A whole-food Wild Alaskan Salmon Oil providing a low concentration of EPA and DHA, suitable for those who value natural sourcing over high potency.
Buy for $16.07(from Vitacost)
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92 Value Omega-3 Fish Oil 1250 mg

Omega-3 Fish Oil 1250 mg

SR Sports Research
4.8
★★★★★
(92408 ratings)
EPA (Eicosapentaenoic Acid): 690 mg
A highly concentrated, single-softgel omega-3 supplement offering excellent EPA and DHA, combined with an outstanding price and massive customer approval.
Buy for $27.97(from iHerb)
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65 Value Omega 3 Fish Oil Concentrate

Omega 3 Fish Oil Concentrate

Solgar
4.8
★★★★★
(24976 ratings)
EPA (Eicosapentaenoic Acid): 320 mg
This economical softgel provides 320mg EPA and 200mg DHA per serving, suitable for basic, general omega-3 supplementation.
Buy for $19.3(from iHerb)
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60 Budget Wild Alaskan Salmon Oil 1000 mg

Wild Alaskan Salmon Oil 1000 mg

Natural Factors OmegaFactors
4.8
★★★★★
(6208 ratings)
EPA (Eicosapentaenoic Acid): 80 mg
A larger, more economical pack of Wild Alaskan Salmon Oil, offering a low concentration of EPA and DHA for those who prefer natural, whole-food omega-3 sourcing.
Buy for $24.47(from Vitacost)
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96 Value Triple Strength Omega-3

Triple Strength Omega-3

InnovixLabs
4.8
★★★★★
(2694 ratings)
EPA (Eicosapentaenoic Acid): 480 mg
This "Triple Strength" omega-3 supplement offers a highly concentrated and potent dose of EPA and DHA per capsule at an exceptionally low price, supporting comprehensive health goals.
Buy for $49.99(from iHerb)
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analyticsProduct stats
sellPrice per product
Average$33.77
Median$29.29
restaurantPrice per serving
Average$0.61
Median$0.52
sciencePrice per 100 mg
Average$0.19
Median$0.11
bar_chartPrice distribution
bar_chartPrice per serving distribution
bar_chartPrice per 100 mg
Reference amount: 100 mg
bar_chartPaired ingredients

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