Zinc
Description
Zinc is an essential trace mineral involved in numerous bodily functions, acting as a cofactor for over 300 enzymes. It plays a critical role in immune system function, helping to fight off infections and support the development and function of immune cells. Zinc is also vital for cell growth and division, DNA synthesis, and protein synthesis, making it essential for overall development and tissue repair. Beyond its fundamental roles, zinc contributes significantly to wound healing, often used topically and orally for skin health. It is also crucial for sensory functions, particularly taste and smell, and a deficiency can lead to altered perception of these senses. Furthermore, zinc is important for normal growth and development during pregnancy, childhood, and adolescence, and contributes to reproductive health. Maintaining adequate zinc levels is important for antioxidant defense, as it helps reduce oxidative stress, and for proper thyroid function. Its widespread involvement in metabolic processes underscores its importance for maintaining overall health and well-being.
Sources
OystersRed meat (beef, pork)PoultryBeansNuts (cashews, almonds)Whole grainsDairy products (milk, yogurt)Certain seafood (crab, lobster)Fortified cereals
Cheapest Zinc supplements
Best Zinc supplements
Value Zinc Supplements Comparison
Timing & Intake
AnytimeWith food
Can be taken with food to minimize gastrointestinal discomfort like nausea.
Daily Intake
RDA (Men)11 mg
RDA (Women)8 mg
RDI11 mg
Optimal Dosage
Minimum15 mg
Maximum30 mg
Safety & Toxicity
Upper Limit (UL)40 mg
Toxicity Threshold100 mg
Toxicity EffectNausea, vomiting, immune suppression
Goals
Digestive Health
Impact
Highest effect
Typical dose:15–30 mg
Zinc is a key cofactor for enzymes involved in cell repair and regeneration. It plays a direct role in regulating the stability of intestinal tight junctions, and deficiency can lead to increased gut permeability. A well-absorbed form like zinc carnosine is particularly effective.
View goal →
Hair Health
Impact
Highest effect
Typical dose:15–30 mg
Zinc is vital for DNA and RNA production, which is required for the normal division of hair follicle cells, leading to healthier hair growth. It also helps balance hormones and keep the oil glands around the follicles working properly. Supplementation can be highly effective for hair loss caused by zinc deficiency.
View goal →
Immunity
Impact
Highest effect
Typical dose:15–50 mg
Zinc is a critical cofactor for hundreds of enzymes and is vital for immune cell (T-cells, NK cells) proliferation and communication. Adequate levels are required for a proper immune response, while acute supplementation can inhibit viral replication in the upper respiratory tract.
View goal →
Metabolism Boost
Impact
Highest effect
Zinc is required for the synthesis of Thyroid Releasing Hormone (TRH) and for the proper function of thyroid receptors. It also plays a key role in insulin synthesis, storage, and secretion. A deficiency in zinc can directly impair both thyroid function and insulin sensitivity, making adequate levels foundational for a healthy metabolism.
View goal →
Productivity Boost
Impact
Highest effect
Zinc is highly concentrated in the brain and plays a vital role in synaptic plasticity and communication between neurons. It also acts as an antioxidant. Deficiency can impair learning, memory, and mood, making adequate levels a key component of optimal cognitive function.
View goal →
Interactions
Positive Interactions
Vitamin C
Both zinc and Vitamin C are crucial for immune function and are often taken together for synergistic immune support.
Vitamin A
Zinc is necessary for the metabolism and utilization of Vitamin A, including its transport from the liver and conversion to its active form.
Biotin
Zinc is a cofactor for enzymes involved in biotin metabolism.
Folate
Zinc is involved in the absorption and metabolism of folate.
Vitamin B6
Zinc and Vitamin B6 are cofactors for many enzymes and work synergistically in various metabolic pathways.
Vitamin D
Both zinc and Vitamin D are important for immune function and bone health, potentially offering complementary benefits.
Magnesium
Zinc and Magnesium often work together in various enzymatic reactions and cellular processes, supporting overall metabolic health.
Selenium
Both zinc and selenium are important antioxidants and support immune function, often found together in immune support formulations.
Negative Interactions
Iron
High doses of zinc can inhibit the absorption of iron, and vice versa. It's often recommended to take them at different times or in balanced ratios.
Copper
High doses of zinc can interfere with copper absorption, potentially leading to copper deficiency. Zinc supplements sometimes include copper to maintain balance.
Calcium
Very high doses of calcium might slightly interfere with zinc absorption, though this interaction is generally less significant compared to iron or copper.
Recommended products
Budget 
Zinc Gluconate 50 mg
AN Amazing Nutrition Amazing Formulas
Zinc: 50 mg
A very economical 50mg zinc gluconate supplement, offering a large quantity for long-term, high-dose zinc support.
Budget 
Zinc 50 mg
NOW
Zinc: 50 mg
An extremely economical 50mg zinc supplement, suitable for those needing a high dose at a budget-friendly price, though the zinc form is not specified.
Budget 
Zinc Gluconate 30 mg
Swanson
Zinc: 30 mg
Swanson's Zinc Gluconate delivers 30mg of zinc in a common form at an outstanding price, ideal for economical daily support.
Budget 
Zinc 30 mg
Nature Made
Zinc: 30 mg
An extremely affordable and popular 30 mg Zinc Gluconate supplement, offering a standard and well-tolerated form for daily zinc needs.
Budget 
Zinc 50 mg
Nature's Bounty
Zinc: 50 mg
An extremely popular and budget-friendly 50mg zinc gluconate supplement, offering strong support for general health and immunity.
Budget 
Zinc 50 mg
Spring Valley
Zinc: 50 mg
Spring Valley's Zinc offers a high 50mg dose at an incredibly low price, but the unspecified zinc form raises concerns about its quality and absorption.
Value 
Zinc Citrate 50 mg
21st Century
Zinc: 50 mg
A highly economical and popular zinc citrate supplement providing a strong 50 mg dose for robust support.
Best 
Chelated Zinc 30 mg
Carlson
Zinc: 30 mg
Carlson's Chelated Zinc delivers 30mg of highly absorbable Zinc Glycinate Chelate, making it a reliable and gentle option for daily zinc support.
Value 
Chelated Zinc 50 mg
21st Century
Zinc: 50 mg
This product delivers a high dose of chelated zinc for targeted support of various bodily functions, complemented by a smaller amount of calcium for general mineral intake.
Best 
Zinc Picolinate 50 mg
Bluebonnet
Zinc: 50 mg
A high-dose 50 mg Zinc Picolinate supplement, offering a well-absorbed form for targeted needs, but at a moderately higher price point.
Best 
OptiZinc 30 mg
Solaray
Zinc: 30 mg
Featuring 30mg of OptiZinc (zinc monomethionine) and 20mg of Vitamin B6, this supplement offers a well-absorbed zinc form for robust nutritional support.
Best 
Zinc Bisglycinate 30 mg
Thorne
Zinc: 30 mg
A premium 30mg Albion Zinc Bisglycinate Chelate from Thorne, offering superior absorption and gentle digestion for comprehensive health support.
Best 
Chelated Zinc
Bluebonnet
Zinc: 30 mg
A high-quality, chelated zinc bisglycinate supplement from Bluebonnet, offering excellent absorption and a suitable 30 mg dose for daily wellness.
Best 
Liposomal Zinc 50
Codeage
Zinc: 50 mg
A high-dose liposomal zinc gluconate supplement that aims for enhanced absorption, but comes at a higher price point.
Best 
Quercetin Zinc+
DEVA
Zinc: 25 mg
A comprehensive immune support supplement combining high-dose, absorbable zinc with Quercetin and other botanicals, but featuring an extremely low copper content which creates a significant mineral imbalance.
No image
Zinc 50 mg
Vitamatic
Zinc: 50 mg
An extremely economical 50mg Zinc Gluconate, offering a high dose of a common zinc form at an exceptionally low price for potent health support.
Best 
Zinc Glycinate
NOW
Zinc: 30 mg
A highly bioavailable Zinc Bisglycinate at a strong 30mg dose, paired with pumpkin seed oil, offering excellent value for comprehensive health support.
Value 
Zinc Citrate 30 mg
Best Naturals
Zinc: 30 mg
A 30mg zinc citrate tablet supplement, offering a balanced, well-absorbed dose for daily general health and immune support.
Value 
Zinc Chelate 30 mg
Nature's Way
Zinc: 30 mg
An outstandingly economical and highly popular zinc bisglycinate chelate supplement, providing excellent absorption at a great daily dose.
Value 
Zinc Picolinate 30 mg
Paradise Earth's Blend
Zinc: 30 mg
An economical and popular multi-ingredient blend providing 30 mg Zinc Picolinate with various superfood, probiotic, and adaptogen complexes for comprehensive wellness support.
Value 
Zinc Amino Acid Chelate 50 mg
Source Naturals
Zinc: 50 mg
A potent 50mg zinc amino acid chelate tablet, thoughtfully paired with copper to support mineral balance during high zinc intake, at an exceptionally low price.
Value 
Zinc Citrate 50 mg
Swanson Premium Brand
Zinc: 50 mg
A high-dose zinc citrate supplement that is very economical, suitable for those looking for broad mineral support.
Best 
High Absorption Zinc Bisglycinate 50 mg
Doctor's Best
Zinc: 50 mg
An excellent value, high-absorption zinc bisglycinate chelate supplement, providing a potent 50 mg dose in a vegetarian-friendly capsule.
Best 
Zinc Picolinate 50 mg
Bluebonnet
Zinc: 50 mg
A high-dose 50mg Zinc Picolinate from Bluebonnet, leveraging a premium, highly absorbed form, best suited for those with higher zinc needs despite a higher price point.
Value 
Zinc Picolinate 50 mg
NOW
Zinc: 50 mg
A highly popular and affordable 50mg zinc picolinate supplement, known for good absorption but at a dose best suited for targeted use.
Product stats
Price per product
Average$28.51
Median$24.19
Price per serving
Average$0.72
Median$0.59
Price per 10 mg
Average$0.45
Median$0.33
Price distribution
Price per serving distribution
Price per 10 mg
Reference amount: 10 mg
Forms
Paired ingredients
Ingredient forms
Zinc Citrate (209) 75
Zinc citrate is a salt of zinc and citric acid. It is known for its good bioavailability and is often chosen for dietary supplements due to its effectiveness and generally good tolerability.
Pros
- Good absorption rate
- Generally well-tolerated
- Cost-effective
Cons
- May cause mild GI upset in sensitive individuals or at high doses
Per product
Avg$30.92
Med$25.99
Per serving
Avg$0.90
Med$0.62
Per 10 mg
Avg$0.38
Med$0.27
Price distribution
Zinc Oxide (136) 30
Zinc oxide is a widely used ingredient in topical preparations like sunscreens and diaper rash creams due to its protective and soothing properties. However, its oral absorption for systemic zinc supplementation is very poor, making it less effective than other forms for internal use.
Pros
- Very inexpensive
- Excellent for topical applications (sunscreen, skin protectant)
- Antiseptic and astringent properties when applied externally
Cons
- Extremely poor oral bioavailability for systemic zinc supplementation
- Less effective for addressing internal zinc deficiencies
Per product
Avg$22.42
Med$19.18
Per serving
Avg$0.44
Med$0.25
Per 10 mg
Avg$0.25
Med$0.13
Price distribution
Zinc Picolinate (101) 85
Zinc picolinate is formed by binding zinc to picolinic acid, a natural chelate produced in the body. Research suggests it offers superior absorption compared to other common forms like zinc gluconate or citrate, making it highly effective for supplementing zinc levels.
Pros
- Excellent bioavailability and absorption
- Well-researched for superior uptake
- Generally well-tolerated
Cons
- Potentially higher cost than less bioavailable forms
Per product
Avg$32.01
Med$24.32
Per serving
Avg$0.63
Med$0.51
Per 10 mg
Avg$0.35
Med$0.26
Price distribution
Zinc Gluconate (96) 70
Zinc gluconate is a zinc salt of gluconic acid. It is one of the most popular forms of zinc used in dietary supplements and cold lozenges due to its good absorption and reasonable cost. It's generally well-tolerated and effective for routine zinc supplementation.
Pros
- Widely available and cost-effective
- Good absorption
- Commonly used in lozenges for immune support
Cons
- Absorption may be slightly lower than highly chelated forms (e.g., picolinate, bisglycinate)
- Can cause mild GI upset in some individuals
Per product
Avg$22.51
Med$19.95
Per serving
Avg$0.68
Med$0.58
Per 10 mg
Avg$0.36
Med$0.30
Price distribution
Zinc Bisglycinate (65) 90
Zinc bisglycinate, also known as zinc glycinate, is a chelated form where zinc is bound to two glycine amino acid molecules. This chelation protects zinc from inhibitors in the gut, leading to superior absorption and significantly reduced gastrointestinal upset compared to other forms. It is considered one of the most effective and well-tolerated zinc supplements.
Pros
- Superior bioavailability and absorption
- Excellent gastrointestinal tolerability (less stomach upset)
- Effective at lower doses
- Suitable for sensitive individuals
Cons
- Generally higher cost than unchelated or less bioavailable forms
Per product
Avg$28.32
Med$26.68
Per serving
Avg$0.58
Med$0.60
Per 10 mg
Avg$0.38
Med$0.40
Price distribution
Zinc Amino Acid Chelate (45) 80
Zinc amino acid chelate refers to zinc bound to amino acids (e.g., glycine, methionine, aspartate). This chelation process protects zinc from dietary inhibitors, improving its absorption and bioavailability compared to inorganic forms like zinc oxide. The specific amino acid(s) used can influence the exact absorption profile and tolerability.
Pros
- Improved absorption and bioavailability over inorganic forms
- Generally well-tolerated with reduced GI upset
- Offers a balance of efficacy and cost-effectiveness
Cons
- Specific bioavailability can vary depending on the amino acid used for chelation
- Less specific than named chelates (e.g., bisglycinate, picolinate)
Per product
Avg$28.45
Med$23.93
Per serving
Avg$0.76
Med$0.49
Per 10 mg
Avg$0.51
Med$0.30
Price distribution
Zinc Bisglycinate Chelate (45) 90
Zinc bisglycinate chelate is a premium form of zinc where zinc is molecularly bonded to two glycine molecules. This stable chelate structure ensures it passes through the digestive tract largely intact, preventing interactions with other dietary components that could inhibit absorption. This leads to superior bioavailability and exceptional gastrointestinal tolerability, making it ideal for those seeking maximum efficacy and minimal stomach upset.
Pros
- Superior bioavailability and absorption due to stable chelate structure
- Excellent gastrointestinal tolerability (minimal stomach upset)
- Effective at lower doses, ideal for sensitive individuals
- Often a preferred choice for high-quality supplementation
Cons
- Generally higher cost than less bioavailable or unchelated forms
Per product
Avg$30.20
Med$27.16
Per serving
Avg$0.71
Med$0.52
Per 10 mg
Avg$0.51
Med$0.38
Price distribution
Zinc Aspartate (32) 75
Zinc aspartate is a form of zinc where the mineral is chelated with aspartic acid, an amino acid. This chelation enhances its absorption compared to inorganic forms, making it a bioavailable option for zinc supplementation. It is often included in mineral complexes.
Pros
- Good absorption and bioavailability
- Generally well-tolerated
- Often combined with other minerals (e.g., ZMA formulations)
Cons
- Less widely researched or common compared to gluconate or picolinate for individual supplementation
- May cause mild GI upset in sensitive individuals or at high doses
Per product
Avg$23.00
Med$23.08
Per serving
Avg$0.64
Med$0.66
Per 10 mg
Avg$0.32
Med$0.19
Price distribution
Zinc Monomethionine (23) 88
Zinc monomethionine is a unique chelated form where zinc is bound to the amino acid L-methionine. This specific chelate is designed for superior absorption and retention in the body compared to other zinc forms. Brands like OptiZinc® are known for utilizing this form, emphasizing its enhanced bioavailability and sustained benefits.
Pros
- Excellent bioavailability and absorption
- Good retention in the body for sustained benefits
- Generally well-tolerated
- Often considered a premium form for efficacy
Cons
- Typically higher cost due to specialized chelation and often proprietary formulations
Per product
Avg$32.38
Med$28.57
Per serving
Avg$1.02
Med$0.73
Per 10 mg
Avg$0.38
Med$0.24
Price distribution