Pyridoxal 5'-Phosphate
Thorne
Score 88
This is a high-potency supplement providing Vitamin B6 as Pyridoxal 5'-Phosphate, its active and more bioavailable form, for targeted metabolic and neurological support.
Score 88
This is a high-potency supplement providing Vitamin B6 as Pyridoxal 5'-Phosphate, its active and more bioavailable form, for targeted metabolic and neurological support.
Analysis
Thorne's Pyridoxal 5'-Phosphate (P5P) is a focused supplement designed to provide Vitamin B6 in its most active and readily usable form. It is particularly suitable for individuals who may have difficulty converting the standard pyridoxine hydrochloride form of B6 into P5P, or for those seeking potent support for various metabolic and neurological functions.
P5P is a crucial cofactor in over 100 enzymatic reactions in the body, supporting everything from amino acid metabolism to neurotransmitter synthesis. This makes it a key nutrient for brain health, nerve function, energy production, and overall cellular processes.
The product delivers a substantial dose of 33.80mg of P5P per capsule, offering significant support for those with specific B6 needs. It comes as a single-ingredient capsule, allowing for precise and unadulterated supplementation of this vital nutrient.
Pros
- Uses the active, most bioavailable form of Vitamin B6 (P5P).
- High potency, suitable for specific or higher B6 needs.
- Single ingredient, no unnecessary fillers or blends.
- Good number of servings per bottle.
Cons
- Very high dosage, may be more than what most individuals need daily without specific guidance.
- Higher price point per bottle, though price per serving is reasonable for the quality.
Warnings
- Due to the high dosage, individuals should consult a healthcare professional, especially if taking other supplements or medications, or for long-term daily use.
- Very high doses of B6 can sometimes lead to nerve-related discomfort in sensitive individuals, though P5P is generally considered less prone to this than pyridoxine HCl.
$56.00($0.31 per serving)
 Pure Formulas | $ 56.00 | |
 iHerb | $ 56.00 | |
 Amazon | $ 56.00 |
Goals
Impact
Highest effect
As a critical coenzyme in over 100 metabolic reactions, P5P directly supports the metabolism of amino acids, carbohydrates, and fats, contributing significantly to overall energy production and cellular function.
Impact
Highest effect
P5P is essential for neurotransmitter synthesis and overall nerve function, directly supporting various aspects of brain health and communication within the nervous system. Its active form ensures better utilization.
Impact
Highest effect
P5P is vital for the synthesis of several neurotransmitters, including serotonin and dopamine, which are key regulators of mood. Adequate P5P levels can therefore contribute to emotional balance.
Impact
Highest effect
By supporting neurotransmitter production and nerve health, P5P can contribute to clearer thinking, memory, and overall cognitive function. A healthy nervous system is foundational for optimal cognition.
Impact
High effect
P5P's role in neurotransmitter balance and nerve function can help support mental clarity and focus, allowing for better concentration and sustained attention.
Impact
High effect
Through its roles in energy metabolism and brain health, P5P can indirectly support sustained mental energy and clarity, which can contribute to improved productivity.
Impact
Moderate effect
Vitamin B6, particularly in its active form, plays a role in homocysteine metabolism. Balanced homocysteine levels are considered important for cardiovascular health.
Impact
Moderate effect
Similar to heart health, P5P's involvement in homocysteine metabolism can offer supportive benefits for the cardiovascular system, contributing to overall health.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 33.8 mg |
Vitamin B6 95
This product specifically provides Vitamin B6 in its highly active and bioavailable Pyridoxal 5'-Phosphate (P5P) form, making it an excellent choice for optimizing B6 intake and utilization.
Alternative products
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BioCoenzymated Pyridoxal 5'-Phosphate 50 mg
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Offering a slightly higher dose of active P-5-P than your current product at a lower price per serving, this is a strong value choice from a reputable brand for consistent B6 support.
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P-5-P 100 mg
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B6 Complex
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This comprehensive B-complex includes both P-5-P and Pyridoxine HCl, potentially offering broader support for overall B vitamin functions that enhance B6's role in your body's systems.
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BioCoenzymated Pyridoxal 5'-Phosphate 50 mg
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This alternative provides a higher dose of the active P-5-P form of B6 at a lower cost per serving, making it a more economical option for direct B6 support.
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Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
This option delivers a much higher dose of the active P-5-P form of B6 for a significantly lower price per serving, offering excellent potency and value.
85 Budget
P-5-P 50 mg
Nutricost
This is a highly economical way to get the active P-5-P form of Vitamin B6, providing a good dose at a very low price per serving to support your goals.
85 Value
P-5-P 50 mg
Nutricost
This alternative provides the active P-5-P form of B6 at a remarkable price per serving, offering great value for supporting various bodily functions, including mood and cognitive health.
88 Value
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
This is an excellent value for an active P-5-P form of B6, providing effective support for your brain and nervous system at a highly competitive price per serving.
88 Value
BioCoenzymated Pyridoxal 5'-Phosphate 50 mg
Natural Factors
Offering a slightly higher dose of active P-5-P than your current product at a lower price per serving, this is a strong value choice from a reputable brand for consistent B6 support.
90 Performance
Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
This alternative offers a significantly higher dose of the active P-5-P form of B6, which may provide more robust support for your energy metabolism, cognitive function, and mood goals.
88 Performance
P-5-P 100 mg
Nutricost
With a higher potency of the active P-5-P form, this product can offer enhanced support for the many roles B6 plays in the body, from brain health to overall metabolism.
88 Performance
B6 Complex
Pure Encapsulations
This comprehensive B-complex includes both P-5-P and Pyridoxine HCl, potentially offering broader support for overall B vitamin functions that enhance B6's role in your body's systems.