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Heart Health Complex

Thorne
4.7
★ ★ ★ ★ ★
(1010 ratings)
Hawthorn 350 mg
Taurine 900 mg
Coenzyme Q-10 45 mg
Product Image
Score77
Useful magnesium and taurine amounts anchor a focused heart-support blend with hawthorn and CoQ10. Incomplete extract details and premium value are its main weaknesses.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Heart Health
Cardiovascular Support
Anti-Aging
Fitness
Anti-Inflammatory Support
Detoxification

Score 77

Useful magnesium and taurine amounts anchor a focused heart-support blend with hawthorn and CoQ10. Incomplete extract details and premium value are its main weaknesses.
How scoring works
$43.00($1.43 per serving)
Vitacost
$ 43.03
Pure Formulas
$ 43.00
iHerb
$ 43.00
Amazon
$ 43.00
Report prices

Analysis

Taurine at 900 mg and magnesium malate at 200 mg provide the most substantial support for cardiac muscle, energy, and electrolyte balance. Potassium citrate adds a smaller 95 mg amount rather than serving as a major potassium supplement.

Hawthorn extract at 350 mg and CoQ10 at 45 mg broaden the cardiovascular approach. Hawthorn lacks active-marker or extract-ratio details, and the CoQ10 molecular form is not identified, making those contributions less precise.

Three capsules per serving are manageable, but the serving cost is high. The formula is best suited to users seeking a broad heart-focused combination rather than dedicated high-dose CoQ10 or potassium.

Who is it for
  • Adults seeking a broad cardiovascular nutrient formula
  • People who want taurine with magnesium and hawthorn
  • Users whose heart and blood-pressure medicines have been reviewed
Best for
  • Cardiovascular nutrient support
  • Magnesium and taurine supplementation
  • Multi-ingredient heart formulas

Pros

  • Provides 900 mg taurine
  • Uses Albion dimagnesium malate
  • Includes potassium citrate
  • Keeps every ingredient amount disclosed

Cons

  • CoQ10 is modest at 45 mg
  • CoQ10 molecular form is not stated
  • Hawthorn lacks active-marker standardization
  • Serving value is only moderate

Warnings

  • Hawthorn may add to the effects of blood-pressure or heart medicines, so those combinations need clinician review.
  • Magnesium can interfere with absorption of levothyroxine and some tetracycline or quinolone antibiotics when taken together.
  • CoQ10 may alter warfarin response, making anticoagulation monitoring important.

Nutrient quality

87 Highest impact

Branded dimagnesium malate and citrate potassium support quality, while hawthorn and CoQ10 lack form details; taurine and hawthorn are substantial, while CoQ10 is modest for a dry capsule. Amounts are generally balanced, though hawthorn may compound blood-pressure and cardiac medicines; the ingredient set coherently supports several cardiovascular pathways; the concise formula has no obvious filler actives.

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Ingredient transparency

77 High impact

Every listed active has a specific amount; no proprietary blend hides key doses. Most forms are specific, but hawthorn species, standardization, and the CoQ10 molecular form are missing; serving directions and inactive ingredients are not included in the supplied details.

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Customer satisfaction

73 High impact

The supplied aggregate average is very favorable, though no individual feedback is available; the large rating sample improves confidence in the aggregate average, but no individual feedback is supplied. Detailed feedback is absent, so repeated complaints cannot be assessed; real-world fit with the intended purpose remains uncertain.

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Value for money

69 High impact

Strong formula coherence partly supports the premium positioning; meaningful taurine and hawthorn help, but modest CoQ10 weakens serving value. Every active contributes to the central purpose; the price is somewhat high compared with similar heart-support combinations.

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Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A Goal FitB+ Strength of SupportA CoverageA Formula Quality
Magnesium · 200 mgCoenzyme Q-10 · 45 mgTaurine · 900 mg

Magnesium, taurine, hawthorn, and CoQ10 address vascular tone, cardiac contraction, and cellular energy in a genuinely heart-focused formula. Evidence is strongest for the mineral and CoQ10 pathways, while hawthorn is more situation dependent.

Taurine, magnesium, and hawthorn are supplied at useful amounts, but CoQ10 and potassium are more modest. Hawthorn and taurine may add to the effect of blood-pressure-lowering medicines and could increase lightheadedness in susceptible users.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Hawthorn Supportive 27 studies
Magnesium Supportive 158 studies
Potassium Supportive 182 studies
Taurine Supportive 25 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitB Strength of SupportB+ CoverageA Formula Quality
Potassium · 95 mgMagnesium · 200 mgCoenzyme Q-10 · 45 mgTaurine · 900 mgHawthorn · 350 mg

Magnesium, taurine, hawthorn, and CoQ10 form a well-aligned blend for vascular tone, rhythm, circulation, and cardiac energy. Each principal active is relevant, although CoQ10 and taurine are below many commonly researched amounts.

Dimagnesium malate and clearly disclosed individual doses support confidence in the formula. Hawthorn can add to the effects of digoxin or blood-pressure medicines, and the potassium content deserves caution in advanced kidney disease.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Hawthorn Supportive 28 studies
Magnesium Supportive 123 studies
Potassium Supportive 117 studies
Taurine Supportive 24 studies
Anti-Aging
Anti-Aging
Impact
High effect
B Goal FitB- Strength of SupportB+ CoverageA Formula Quality
Coenzyme Q-10 · 45 mgMagnesium · 200 mgTaurine · 900 mg

Taurine, CoQ10, magnesium, potassium, and hawthorn create a broad cardiovascular and cellular-support formula. The taurine amount is substantial, but CoQ10 is low and human evidence for taurine as a direct anti-aging intervention remains limited.

The mineral forms are clearly identified, while dry-capsule CoQ10 has no stated molecular form or lipid carrier. Hawthorn may amplify blood-pressure or heart medicines, so users taking those drugs need individualized oversight.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Magnesium Supportive 12 studies
Taurine Supportive 3 studies
Fitness
Fitness
Impact
High effect
D+ Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Magnesium · 200 mg

Magnesium, taurine, potassium, and coenzyme Q10 offer some support for muscle function and cellular energy, but the formula is designed more for cardiovascular wellness than sports performance. Hawthorn further centers the product on heart support rather than training outcomes.

The magnesium form is appealing and the 900 mg taurine amount is relevant, while potassium and coenzyme Q10 are modestly supplied. It provides a coherent supportive formula but lacks direct power, blood-flow, hydration, and muscle-repair depth.

Study evidence
Magnesium Disputed 29 studies
Potassium No effect 7 studies
Taurine Supportive 21 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitC- Strength of SupportC+ CoverageB Formula Quality
Coenzyme Q-10 · 45 mgTaurine · 900 mg

Taurine provides the clearest goal-relevant contribution through antioxidant and cytokine-modulating roles, while CoQ10, hawthorn, magnesium, and potassium broaden cellular and cardiovascular support. The broad formula is plausible, but the low CoQ10 amount and limited extract details reduce confidence in its anti-inflammatory depth.

Several ingredients fit together well for cardiovascular support, yet that purpose is wider than targeted inflammatory pathway support. Hawthorn may add to the effects of blood-pressure or cardiac medicines, and the added potassium warrants caution with potassium-retaining drugs or impaired kidney function.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Magnesium Supportive 41 studies
Taurine Supportive 12 studies
Detoxification
Detoxification
Impact
High effect
C Goal FitB- Strength of SupportC CoverageC+ Formula Quality
Magnesium · 200 mgTaurine · 900 mg

Taurine supports bile-acid conjugation, while magnesium and CoQ10 add metabolic and antioxidant roles. The formula touches several mechanisms relevant to liver function despite being designed mainly for cardiovascular support.

Taurine approaches a useful amount, but CoQ10 is modest and hawthorn contributes little to metabolic clearance. The mixed goal focus limits depth compared with a dedicated NAC or standardized milk thistle product.

Study evidence
Magnesium Supportive 19 studies
Taurine Supportive 2 studies

Ingredients

IngredientAmount per serving
Magnesium (Albion DiMagnesium Malate)
 200 mg
Potassium (Potassium Citrate)
 95 mg
Taurine
900 mg
Hawthorn extract
350 mg
Coenzyme Q10
45 mg
Gluten Free Adults 18–50
Report overview
Hawthorn · 350 mg OverallScore52
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The extract provides an effective amount, but standardization, plant part, and species are not disclosed. No specified synthetic additives appear in the supplied ingredient data. Value is weak for hawthorn alone because the serving cost is high.

View ingredientView products
Taurine · 900 mg OverallScore50
C- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value

The serving provides a substantial taurine amount that approaches the highest potency tier. The label does not specify a higher-grade form, traceable source, or independent certification. Requiring three capsules and carrying a high taurine-normalized cost reduces its appeal as a dedicated taurine option.

View ingredientView products
Coenzyme Q-10 · 45 mg OverallScore31
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyD- Value

Taurine, hawthorn, magnesium, and potassium create a broad heart-support formula around a small CoQ10 amount. Dry capsules and an unspecified molecular form limit likely CoQ10 absorption and effectiveness. Hawthorn may alter blood pressure or heart-drug effects, so users taking those medicines should seek individualized guidance.

View ingredientView products
Loading alternative details
80 Performance

Clinical Cardio

NOW
<p>Stronger formulation focus comes from standardized hawthorn, 50 mg CoQ10, vitamin K2, vitamin D3, grape seed, and carnitine. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, standardized hawthorn and the added vitamin K2 and grape-seed extract improve formulation detail while preserving strong value.</p>
65 Performance

Blood Pressure Support

Bluebonnet Targeted Choice
<p>Stronger formulation focus comes from 150 mg magnesium, 250 mg taurine, 150 mg hawthorn, arginine, hibiscus, olive leaf, grape seed, and 20 mg CoQ10. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the broader vascular-support mix is more targeted to blood-pressure support, but many key amounts are modest and medicine interactions remain relevant.</p>
69 Performance

Blood Pressure Wellness

Bio Nutrition
<p>Stronger formulation focus comes from 300 mg hawthorn, 50 mg ubiquinone CoQ10, magnesium, potassium, garlic, and celery seed. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the same CoQ10 amount is paired with broader cardiovascular ingredients at lower recurring cost, though medicine interactions need attention.</p>
78 Budget

CoQ10 100 mg

NOW
<p>Lower recurring cost is paired with 100 mg CoQ10 and 400 mg hawthorn berry in clearly disclosed amounts. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, it more than doubles the CoQ10 amount and supplies substantially more hawthorn while remaining simple to assess.</p>
64 Budget

Blood Pressure Support

Bluebonnet Targeted Choice
<p>Lower recurring cost is paired with magnesium, 250 mg taurine, 150 mg hawthorn, arginine, hibiscus, olive leaf, grape seed, and CoQ10. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the formula adds several vascular ingredients at lower recurring cost, though most are modestly dosed.</p>
69 Budget

Blood Pressure Wellness

Bio Nutrition
<p>Lower recurring cost is paired with 300 mg hawthorn, 50 mg ubiquinone CoQ10, magnesium, potassium, garlic, and celery seed. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the same CoQ10 amount is paired with broader cardiovascular ingredients at lower recurring cost, though medicine interactions need attention.</p>
78 Value

CoQ10 100 mg

NOW
<p>A better quality-to-cost balance comes from 100 mg CoQ10 and 400 mg hawthorn berry in a focused two-ingredient formula. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the higher CoQ10 and hawthorn amounts strengthen the core cardiovascular pairing, although neither form is highly specified.</p>
64 Value

Blood Pressure Support

Bluebonnet Targeted Choice
<p>A better quality-to-cost balance comes from magnesium, 250 mg taurine, 150 mg hawthorn, arginine, hibiscus, olive leaf, grape seed, and CoQ10. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, the formula adds several vascular ingredients at lower recurring cost, though most are modestly dosed.</p>
80 Value

Clinical Cardio

NOW
<p>A better quality-to-cost balance comes from standardized hawthorn, 50 mg CoQ10, vitamin K2, vitamin D3, grape seed, and carnitine. Compared with the original’s modest, unspecified CoQ10 and higher recurring cost, standardized hawthorn and the added vitamin K2 and grape-seed extract improve formulation detail while preserving strong value.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials.
    Pittler MH; Schmidt K; Ernst E · The American journal of medicine · 2003
    Meta-analysis632 participants13 studies pooledHeart Health forHawthorn
  2. Hawthorn (Crataegus spp.) Clinically Significantly Reduces Blood Pressure in Hypertension: A Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Szikora Z; Mátyus RO; Szabó BV; Csupor D; Tóth B · Pharmaceuticals (Basel, Switzerland) · 2025
    Meta-analysis428 participants6 studies pooledHeart Health Cardiovascular Support forHawthorn
  3. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial.
    Zick SM; Vautaw BM; Gillespie B; Aaronson KD · European journal of heart failure · 2010
    Randomized trial120 participantsHeart Health forHawthorn
  4. Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials.
    Lei L; Liu Y · BMC cardiovascular disorders · 2018
    Meta-analysis2,149 participants14 studies pooledHeart Health forCoenzyme Q-10
  5. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledHeart Health Cardiovascular Support forCoenzyme Q-10
  6. Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study.
    Sun Q; Wang B; Li Y; Sun F; Li P; Xia W; Zhou X; Li Q; Wang X; Chen J; Zeng X; Zhao Z; He H; Liu D; Zhu Z · Hypertension (Dallas, Tex. : 1979) · 2016
    Randomized trial120 participantsCardiovascular Support Heart Health forTaurine
  7. The effects of taurine supplementation on glycemic control and serum lipid profile in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
    Maleki V; Alizadeh M; Esmaeili F; Mahdavi R · Amino acids · 2021
    Randomized trial45 participantsCardiovascular Support Heart Health forTaurine
  8. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  9. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach.
    Rababa'h AM; Altarabsheh SE; Haddad O; Deo SV; Obeidat Y; Al-Azzam S · The heart surgery forum · 2017
    Observational study116 participantsCardiovascular Support forHawthorn
  10. The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis.
    Waldron M; Patterson SD; Tallent J; Jeffries O · Current hypertension reports · 2019
    Meta-analysis103 participants7 studies pooledHeart Health Cardiovascular Support forTaurine
  11. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  12. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  13. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  14. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  15. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  16. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsAnti-Aging Fitness forMagnesium
  17. Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults.
    Dominguez LJ; Mérida DM; Donat-Vargas C; Banegas JR; Veronese N; Barbagallo M; Rodríguez-Artalejo F; Guallar-Castillón P · Journal of the American Medical Directors Association · 2024
    Cohort study1,900 participantsAnti-Aging forMagnesium
  18. Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial.
    Zhu X; Borenstein AR; Zheng Y; Zhang W; Seidner DL; Ness R; Murff HJ; Li B; Shrubsole MJ; Yu C; Hou L; Dai Q · Journal of Alzheimer's disease : JAD · 2021
    Randomized trial250 participantsAnti-Aging forMagnesium
  19. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsAnti-Aging forMagnesium
  20. Interpretable machine learning with SHAP analysis identifies redox-modulating dietary antioxidants for predicting accelerated biological aging.
    Zhang B; Zhang X; Ma L; Li D; Li Y; Lin S; Peng L; He L · Experimental gerontology · 2026
    Cross-sectional study8,125 participantsAnti-Aging forMagnesium
  21. Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women.
    Chupel MU; Minuzzi LG; Furtado GE; Santos ML; Ferreira JP; Filaire E; Teixeira AM · Amino acids · 2021
    Randomized trial48 participantsAnti-Aging forTaurine
  22. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.
    Abud GF; De Carvalho FG; Batitucci G; Travieso SG; Bueno Junior CR; Barbosa Junior F; Marchini JS; de Freitas EC · Nutrition (Burbank, Los Angeles County, Calif.) · 2022
    Randomized trial24 participantsAnti-Aging forTaurine
  23. Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study.
    Domoto T; Kise K; Oyama Y; Furuya K; Kato Y; Nishita Y; Kozakai R; Otsuka R · Frontiers in nutrition · 2024
    Cohort studyAnti-Aging forTaurine
  24. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  25. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  26. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  27. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  28. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  29. Dietary magnesium intake is inversely associated with serum C-reactive protein levels: meta-analysis and systematic review.
    Dibaba DT; Xun P; He K · European journal of clinical nutrition · 2014
    Meta-analysis32,918 participants7 studies pooledAnti-Inflammatory Support forMagnesium
  30. Efficacy and safety of magnesium glycinate as add on therapy in hypomagnesemic asthma and chronic obstructive pulmonary disease patients: A randomised controlled study assessing inflammatory biomarkers.
    Maddirevula MK; Rajanandh MG; Wesley B · Pulmonary pharmacology & therapeutics · 2026
    Randomized trial224 participantsAnti-Inflammatory Support forMagnesium
  31. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsAnti-Inflammatory Support forMagnesium
  32. The effect of long-term magnesium intake on inflammatory markers in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Wang W; Wang J; Yang Y; Shi Y · Frontiers in nutrition · 2025
    Meta-analysis444 participants8 studies pooledAnti-Inflammatory Support forMagnesium
  33. Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials.
    Veronese N; Pizzol D; Smith L; Dominguez LJ; Barbagallo M · Nutrients · 2022
    Meta-analysis889 participants17 studies pooledAnti-Inflammatory Support forMagnesium
  34. Oxidative stress and inflammation in obesity after taurine supplementation: a double-blind, placebo-controlled study.
    Rosa FT; Freitas EC; Deminice R; Jordão AA; Marchini JS · European journal of nutrition · 2015
    Randomized trial24 participantsAnti-Inflammatory Support forTaurine
  35. Effect of taurine supplementation on preventing ventilator-associated pneumonia in pediatrics under mechanical ventilation, a randomized controlled double-blind clinical trial.
    Shirzad-Yazdi N; Shorafa E; Abootalebi SN; Heidari R; Hojabri K; Doostfatemeh M; Masjedi F; Vazin A; Shafiekhani M · Frontiers in pediatrics · 2025
    Randomized trial77 participantsAnti-Inflammatory Support forTaurine
  36. Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise.
    Wang Y; Xu T; Zhao H; Gu C; Li Z · Frontiers in physiology · 2022
    Non-randomized trial10 participantsAnti-Inflammatory Support forTaurine
  37. Exercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.
    Chupel MU; Minuzzi LG; Furtado G; Santos ML; Hogervorst E; Filaire E; Teixeira AM · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018
    Randomized trial48 participantsAnti-Inflammatory Support forTaurine
  38. Taurine supplementation has anti-atherogenic and anti-inflammatory effects before and after incremental exercise in heart failure.
    Ahmadian M; Roshan VD; Aslani E; Stannard SR · Therapeutic advances in cardiovascular disease · 2017
    Randomized trialAnti-Inflammatory Support forTaurine
  39. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  40. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  41. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  42. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  43. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany.
    Wyss C; Gündling PW; Kostev K · Scientific reports · 2024
    Cohort study9,100 participantsCardiovascular Support forHawthorn
  44. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II.
    Degenring FH; Suter A; Weber M; Saller R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial143 participantsCardiovascular Support forHawthorn
  45. [Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II)].
    Weikl A; Assmus KD; Neukum-Schmidt A; Schmitz J; Zapfe G; Noh HS; Siegrist J · Fortschritte der Medizin · 1996
    Randomized trial136 participantsCardiovascular Support forHawthorn
  46. Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without Hawthorn special extract WS 1442.
    Habs M · Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine · 2005
    Cohort study952 participantsCardiovascular Support forHawthorn
  47. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  48. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  49. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  50. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  51. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  52. Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies.
    Gan L; Zhao B; Inoue-Choi M; Liao LM; Graubard BI; Weinstein SJ; Albanes D; Huang J · BMC medicine · 2024
    Meta-analysis416,104 participantsCardiovascular Support forPotassium
  53. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledCardiovascular Support Heart Health forPotassium
  54. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials.
    Geleijnse JM; Kok FJ; Grobbee DE · Journal of human hypertension · 2003
    Meta-analysis27 studies pooledCardiovascular Support forPotassium
  55. Twenty-Four-Hour Urinary Sodium and Potassium Excretion and Their Associations With Blood Pressure Among Adults in China: Baseline Survey of Action on Salt China.
    Li Y; Zhang P; Wu J; Ma J; Xu J; Zhang X; Luo R; Liu M; Sun Y; Li X; Tan M; He FJ; MacGregor GA; Li X · Hypertension (Dallas, Tex. : 1979) · 2021
    Cross-sectional study5,353 participantsCardiovascular Support forPotassium
  56. Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program.
    Wang DD; Li Y; Nguyen XT; Song RJ; Ho YL; Hu FB; Willett WC; Wilson PWF; Cho K; Gaziano JM; Djoussé L; On Behalf Of The Va Million Veteran Program · Nutrients · 2022
    Cohort study180,156 participantsCardiovascular Support forPotassium
  57. Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
    Li Y; Wang Q; Liu Y; Li Q; Xia W; Lin S; Yang Q; Scholze A; Zhao Z; He H; Zhang H; Yan Z; Tepel M; Mu H; Zhu Z; Liu D · iScience · 2025
    Randomized trial165 participantsCardiovascular Support Heart Health forTaurine
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    Tzang CC; Chi LY; Lin LH; Lin TY; Chang KV; Wu WT; Özçakar L · Nutrition & diabetes · 2024
    Meta-analysis1,024 participants25 studies pooledCardiovascular Support forTaurine
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    Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S · Nutrition reviews · 2025
    Meta-analysis34 studies pooledCardiovascular Support forTaurine
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    Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
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    Randomized trialDetoxification forMagnesium
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    Asemi Z; Aarabi MH; Hajijafari M; Alizadeh SA; Razzaghi R; Mazoochi M; Esmaillzadeh A · International journal of preventive medicine · 2020
    Randomized trialDetoxification forMagnesium
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    Daus AT; Freeman WM; Wilson J; Aponte C · The International journal of the addictions · 1985
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  64. Ionized hypomagnesemia in patients undergoing orthotopic liver transplantation: a complication of citrate intoxication.
    Scott VL; De Wolf AM; Kang Y; Altura BT; Virji MA; Cook DR; Altura BM · Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 1997
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    Hu YH; Lin CL; Huang YW; Liu PE; Hwang DF · Amino acids · 2008
    Non-randomized trial24 participantsDetoxification forTaurine
  66. Taurine status and response to intravenous taurine supplementation in adults with short-bowel syndrome undergoing long-term parenteral nutrition: a pilot study.
    Schneider SM; Joly F; Gehrardt MF; Badran AM; Myara A; Thuillier F; Coudray-Lucas C; Cynober L; Trivin F; Messing B · The British journal of nutrition · 2006
    Single-arm trial32 participantsDetoxification forTaurine
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    Cohort study81,524 participantsFitness forMagnesium
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    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
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    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
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    Lana A; Struijk EA; Ortolá R; Rodríguez-Artalejo F; Lopez-Garcia E · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
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    Kjeldsen K; Nørgaard A; Hau C · European journal of clinical investigation · 1991
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  73. Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.
    Zamani P; Shah SJ; Cohen JB; Zhao M; Yang W; Afable JL; Caturla M; Maynard H; Pourmussa B; Demastus C; Mohanty I; Miyake MM; Adusumalli S; Margulies KB; Prenner SB; Poole DC; Wilson N; Reddy R; Townsend RR; Ischiropoulos H; Cappola TP; Chirinos JA · JAMA cardiology · 2025
    Randomized trial84 participantsFitness forPotassium
  74. Potassium Bicarbonate Supplementation Lowers Bone Turnover and Calcium Excretion in Older Men and Women: A Randomized Dose-Finding Trial.
    Dawson-Hughes B; Harris SS; Palermo NJ; Gilhooly CH; Shea MK; Fielding RA; Ceglia L · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Randomized trial244 participantsFitness forPotassium
  75. Exercise-Associated Muscle Cramps in Ironman-Distance Triathletes Over 3 Decades.
    Nilssen PK; Johnson KB; Hiller WDB; Miller TK; Connolly CP · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2026
    Observational study10,533 participantsFitness forPotassium
  76. Taurine supplementation enhances anaerobic power in elite speed skaters: A double-blind, randomized, placebo-controlled, crossover study.
    Buzdağlı Y; Eyipınar CD; Öget F; Şıktar E; Forbes SC; Tekin A · Biology of sport · 2023
    Randomized trial30 participantsFitness forTaurine
  77. The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners.
    Balshaw TG; Bampouras TM; Barry TJ; Sparks SA · Amino acids · 2013
    Randomized trial8 participantsFitness forTaurine
  78. Effects of different doses of taurine supplementation on repeated-sprint performance after exhaustive exercise in a high temperature and humidity environment.
    Cheng X; Lin Y; Li Z · Frontiers in nutrition · 2026
    Randomized trial16 participantsFitness forTaurine
  79. Oral taurine improves critical power and severe-intensity exercise tolerance.
    Waldron M; Patterson SD; Jeffries O · Amino acids · 2020
    Randomized trial12 participantsFitness forTaurine
  80. Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat.
    Page LK; Jeffries O; Waldron M · European journal of sport science · 2019
    Randomized trial11 participantsFitness forTaurine
  81. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  82. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  83. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health forCoenzyme Q-10
  84. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  85. [Actions of standardized extracts of Crataegus berries on exercise tolerance and quality of life in patients with congestive heart failure].
    Rietbrock N; Hamel M; Hempel B; Mitrovic V; Schmidt T; Wolf GK · Arzneimittel-Forschung · 2001
    Randomized trial88 participantsHeart Health forHawthorn
  86. Clinical efficacy of crataegus extract WS 1442 in congestive heart failure NYHA class II.
    Zapfe jun G · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2002
    Randomized trial40 participantsHeart Health forHawthorn
  87. Baseline severity but not gender modulates quantified Crataegus extract effects in early heart failure--a pooled analysis of clinical trials.
    Eggeling T; Regitz-Zagrosek V; Zimmermann A; Burkart M · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Meta-analysis687 participants10 studies pooledHeart Health forHawthorn
  88. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
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    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  90. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  91. Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
    Poorolajal J; Zeraati F; Soltanian AR; Sheikh V; Hooshmand E; Maleki A · PloS one · 2017
    Meta-analysis1,213 participants23 studies pooledHeart Health forPotassium
  92. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study.
    O'Donnell M; Mente A; Rangarajan S; McQueen MJ; O'Leary N; Yin L; Liu X; Swaminathan S; Khatib R; Rosengren A; Ferguson J; Smyth A; Lopez-Jaramillo P; Diaz R; Avezum A; Lanas F; Ismail N; Yusoff K; Dans A; Iqbal R; Szuba A; Mohammadifard N; Oguz A; Yusufali AH; Alhabib KF; Kruger IM; Yusuf R; Chifamba J; Yeates K; Dagenais G; Wielgosz A; Lear SA; Teo K; Yusuf S; PURE Investigators · BMJ (Clinical research ed.) · 2019
    Cohort study103,570 participantsHeart Health forPotassium
  93. Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies.
    D'Elia L; Cappuccio FP; Masulli M; La Fata E; Rendina D; Galletti F · Nutrients · 2023
    Meta-analysis332 participants5 studies pooledHeart Health forPotassium
  94. Effects of potassium supplementation on office, home, and 24-h blood pressure in patients with essential hypertension.
    Kawano Y; Minami J; Takishita S; Omae T · American journal of hypertension · 1999
    Randomized trial55 participantsHeart Health forPotassium
  95. Seafood diets: hypolipidemic and antiatherogenic effects of taurine and n-3 fatty acids.
    Elvevoll EO; Eilertsen KE; Brox J; Dragnes BT; Falkenberg P; Olsen JO; Kirkhus B; Lamglait A; Østerud B · Atherosclerosis · 2009
    Randomized trial80 participantsHeart Health forTaurine
  96. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.
    Guan L; Miao P · European journal of pharmacology · 2021
    Meta-analysis12 studies pooledHeart Health forTaurine