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Glutathione 500 mg

Nutricost
4.7
★ ★ ★ ★ ★
(1063 ratings)
Gluthathione 500 mg
Product Image
Score79
A large supply of 500 mg capsules offers convenient, focused glutathione intake. Unspecified form and delivery details keep absorption confidence limited.
How scoring works
Quantity:240 Capsule(s) • (240 servings)
Goals:
Skin Health

Score 79

A large supply of 500 mg capsules offers convenient, focused glutathione intake. Unspecified form and delivery details keep absorption confidence limited.
How scoring works
$49.09($0.20 per serving)
Vitacost
$ 49.09
iHerb
$ 51.98
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Analysis

The capsule supplies 500 mg of glutathione without unrelated active ingredients. A large number of servings makes the product convenient for consistent use.

Form disclosure is the main weakness because reduced, acetylated, or liposomal delivery is not identified. No branded source or purity details are provided to offset that absorption uncertainty.

The formula may support antioxidant intake, including for skin-focused users, but it does not address collagen, hydration, or barrier lipids. It is best for shoppers who prioritize a substantial direct dose and long supply over enhanced delivery.

Who is it for
  • Adults seeking a long-supply glutathione capsule
  • Users who prefer single-active products
  • Shoppers prioritizing dose quantity and convenience
Best for
  • Basic antioxidant supplementation
  • Long-term capsule routines
  • Avoiding complex antioxidant blends

Pros

  • Substantial 500 mg serving
  • Large serving count
  • Single-active formula
  • Efficient serving value

Cons

  • Reduced form is not identified
  • No liposomal or acetylated delivery
  • No branded source or purity details
  • Limited support beyond antioxidant pathways

Nutrient quality

75 High impact

Generic L-glutathione lacks a reduced, liposomal, or acetylated form that would strengthen absorption confidence. The substantial direct glutathione amount provides strong nominal dose depth.

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Ingredient transparency

78 High impact

Every listed active ingredient has a specific amount. Usage and inactive-ingredient details remain incomplete.

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Customer satisfaction

70 High impact

The average rating is consistently strong. The substantial feedback pool makes the average reasonably dependable.

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Value for money

91 Highest impact

The large nominal dose and economical format support the price despite absorption uncertainty. The large package provides excellent serving value.

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Goals

Skin Health
Skin Health
Impact
Moderate effect
C Goal FitC+ Strength of SupportD- CoverageB Formula Quality
Gluthathione · 500 mg

Glutathione provides focused antioxidant support that may help protect skin from oxidative stress. Its value for visible skin outcomes depends heavily on oral absorption.

The amount is substantial, but the label does not identify reduced, acetylated, or liposomal glutathione. The single-active formula also leaves collagen structure and barrier hydration unaddressed.

Study evidence
Gluthathione Supportive 13 studies

Ingredients

IngredientAmount per serving
L-Glutathione
500 mg
Gluten Free Adults 18–50
Report overview
Gluthathione · 500 mg OverallScore42
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value

The serving provides a substantial amount of direct glutathione at a low cost. However, the label does not identify a reduced, acetylated, or liposomal form, so absorption quality remains uncertain. No branded source, purity testing, or full excipient details are supplied to strengthen confidence in ingredient quality.

View ingredientView products
Loading alternative details
84 Performance

L-Glutathione (Reduced) 500 mg

California Gold Nutrition
<p>Its label clearly provides 500 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
76 Performance

Reduced Glutathione 250 mg

Source Naturals
<p>Its label clearly provides 250 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
79 Performance

Mega-Liposomal Glutathione+ 750 mg Organic Fruit Flavor

Aurora NutraScience
<p>Its label clearly provides 750 mg of L-Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
68 Budget

Deluxe Scavengers

Metabolic Maintenance
<p>Its label clearly provides 100 mg of Coenzyme Q10, preserving relevant glutathione coverage. It is not lower-cost than the original, but it is the closest remaining eligible fit for this category; the input does not provide independent testing or absorption evidence.</p>
74 Budget

Optimal Liposomal Glutathione Plus

Seeking Health
<p>Its label clearly provides 350 mg of L-Glutathione, preserving relevant glutathione coverage. It is not lower-cost than the original, but it is the closest remaining eligible fit for this category; the input does not provide independent testing or absorption evidence.</p>
73 Budget

Chem-Defense Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
72 Value

L-Glutathione 100 mg

Bluebonnet
<p>Its label clearly provides 100 mg of L-Glutathione, Reduced, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
76 Value

L-Glutathione 500 mg

AN Amazing Nutrition Amazing Formulas
<p>Its label clearly provides 500 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the similar serving economics and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
75 Value

Reduced Glutathione Complex 50 mg Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The clinical effect of glutathione on skin color and other related skin conditions: A systematic review.
    Dilokthornsakul W; Dhippayom T; Dilokthornsakul P · Journal of cosmetic dermatology · 2019
    Systematic review4 studies pooledSkin Health forGluthathione
  2. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study.
    Arjinpathana N; Asawanonda P · The Journal of dermatological treatment · 2012
    Randomized trial60 participantsSkin Health forGluthathione
  3. Systemic Glutathione as a Skin-Whitening Agent in Adult.
    Sitohang IBS; Ninditya S · Dermatology research and practice · 2022
    Systematic review3 studies pooledSkin Health forGluthathione
  4. The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
    Duperray J; Sergheraert R; Chalothorn K; Tachalerdmanee P; Perin F · Journal of cosmetic dermatology · 2022
    Randomized trial124 participantsSkin Health forGluthathione
  5. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women.
    Watanabe F; Hashizume E; Chan GP; Kamimura A · Clinical, cosmetic and investigational dermatology · 2014
    Randomized trial30 participantsSkin Health forGluthathione
  6. Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.
    Khanna R; Rambhia P; Chapas A · The Journal of clinical and aesthetic dermatology · 2025
    Systematic review5 studies pooledSkin Health forGluthathione
  7. Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
    Becker K; Pons-Kühnemann J; Fechner A; Funk M; Gromer S; Gross HJ; Grünert A; Schirmer RH · Redox report : communications in free radical research · 2006
    Randomized trialSkin Health forGluthathione
  8. Glutathione and its antiaging and antimelanogenic effects.
    Weschawalit S; Thongthip S; Phutrakool P; Asawanonda P · Clinical, cosmetic and investigational dermatology · 2020
    Randomized trial57 participantsSkin Health forGluthathione