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L-Carnitine 500 mg

Swanson
4.7
★ ★ ★ ★ ★
(4760 ratings)
L-Carnitine 500 mg
Product Image
Score84
500 mg of L-carnitine base offers excellent value, but the focused formula has limited pathway coverage.
How scoring works
Quantity:100 Tablet(s) • (100 servings)
Goals:
Cardiovascular Support

Score 84

500 mg of L-carnitine base offers excellent value, but the focused formula has limited pathway coverage.
How scoring works
$12.09($0.12 per serving)
iHerb
$ 12.09
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Analysis

L-carnitine base provides a clear active amount without requiring salt conversion, and 190 mg of calcium adds a useful mineral contribution. The 500 mg serving is presented in a tablet format for routine use.

No branded purity standard is supplied, and the carnitine amount remains a maintenance dose rather than a high targeted intake. Benefits are most likely when carnitine support is relevant rather than as a universal performance or heart-health effect.

The formula stays focused on fatty-acid transport and cellular energy rather than broad cardiovascular or performance coverage. Excellent value and 100 servings shape the practical appeal.

Who is it for
  • Adults seeking a simple carnitine supplement
  • Users seeking maintenance-level cellular-energy support
Best for
  • Focused fatty-acid transport support
  • Value-conscious carnitine use

Pros

  • Provides 500 mg per labeled serving
  • Clearly identifies L-carnitine base
  • Tablet format
  • Excellent value

Cons

  • No independent purity or testing standard is disclosed
  • No branded raw-material source is identified
  • Supports a narrow metabolic pathway rather than broad cardiovascular coverage

Nutrient quality

83 Highest impact

L-carnitine base provides a direct maintenance amount with clearly listed calcium. No branded purity source or non-active ingredient list is supplied.

Ingredient transparency

85 Highest impact

Active complex amounts and serving details are stated clearly. No branded purity source or non-active ingredient list is supplied.

Customer satisfaction

72 High impact

The supplied average rating is strong, and a very large response volume makes the average rating more stable. No comment-level feedback is supplied to judge recurring complaints or purpose-specific experiences.

Value for money

94 Highest impact

Very efficient serving cost supports excellent value. Formula focus and disclosure determine whether that value holds up in practice.

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Goals

Cardiovascular Support
Impact
Moderate effect
D+ Goal FitC+ Strength of SupportD- CoverageA+ Formula Quality
L-Carnitine · 500 mg

L-carnitine supports fatty-acid transport and cellular energy, which gives it an indirect cardiovascular role. The serving supplies a useful maintenance amount in a very simple formula.

L-carnitine base and its exact amount are clearly disclosed, though no branded purity standard is provided. Evidence for broad cardiovascular benefit in healthy users is less direct than for omega-3s, CoQ10, or magnesium.

Study evidence
L-Carnitine Supportive 73 studies

Ingredients

IngredientAmount per serving
Calcium
190 mg
L-Carnitine base
500 mg
Adults 18–50 Vegetarian
Report overview
L-Carnitine · 500 mg OverallScore81
C Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

L-carnitine base provides a clear elemental amount and fits standard maintenance use. The base form is suitable for the collection, though no branded purity source or testing standard is identified. Its very low cost per gram creates strong value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials.
    Mirrafiei A; Jayedi A; Shab-Bidar S · Clinical therapeutics · 2024
    Meta-analysis2,041 participants21 studies pooledCardiovascular Support forL-Carnitine
  2. Blood Pressure and Metabolic Effects of Acetyl-l-Carnitine in Type 2 Diabetes: DIABASI Randomized Controlled Trial.
    Parvanova A; Trillini M; Podestà MA; Iliev IP; Aparicio C; Perna A; Peraro F; Rubis N; Gaspari F; Cannata A; Ferrari S; Bossi AC; Trevisan R; Parameswaran S; Chávez-Iñiguez JS; Masnic F; Seck SM; Jiamjariyaporn T; Cortinovis M; Perico L; Sharma K; Remuzzi G; Ruggenenti P; Warnock DG · Journal of the Endocrine Society · 2022
    Randomized trial229 participantsCardiovascular Support forL-Carnitine
  3. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis.
    Shang R; Sun Z; Li H · BMC cardiovascular disorders · 2015
    Meta-analysis3,108 participants5 studies pooledCardiovascular Support forL-Carnitine
  4. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
    Koeth RA; Wang Z; Levison BS; Buffa JA; Org E; Sheehy BT; Britt EB; Fu X; Wu Y; Li L; Smith JD; DiDonato JA; Chen J; Li H; Wu GD; Lewis JD; Warrier M; Brown JM; Krauss RM; Tang WH; Bushman FD; Lusis AJ; Hazen SL · Nature medicine · 2013
    Other2,595 participantsCardiovascular Support forL-Carnitine
  5. Associations of circulating choline and its related metabolites with cardiometabolic biomarkers: an international pooled analysis.
    Pan XF; Yang JJ; Shu XO; Moore SC; Palmer ND; Guasch-Ferré M; Herrington DM; Harada S; Eliassen H; Wang TJ; Gerszten RE; Albanes D; Tzoulaki I; Karaman I; Elliott P; Zhu H; Wagenknecht LE; Zheng W; Cai H; Cai Q; Matthews CE; Menni C; Meyer KA; Lipworth LP; Ose J; Fornage M; Ulrich CM; Yu D · The American journal of clinical nutrition · 2021
    Meta-analysis32,853 participants17 studies pooledCardiovascular Support forL-Carnitine
  6. L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes.
    Malaguarnera M; Vacante M; Avitabile T; Malaguarnera M; Cammalleri L; Motta M · The American journal of clinical nutrition · 2009
    Randomized trial81 participantsCardiovascular Support forL-Carnitine
  7. L-Carnitine's Effect on the Biomarkers of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Choi M; Park S; Lee M · Nutrients · 2021
    Meta-analysis9 studies pooledCardiovascular Support forL-Carnitine
  8. The Effects of L-Carnitine on Echocardiographic Changes in Patients With β-Thalassemia Major and Intermedia.
    Shahidi M; Hashemi SR; Fattahi N; Roshani D; Vahedi S; Sharifi P; Moradveisi B · Journal of pediatric hematology/oncology · 2020
    Randomized trial60 participantsCardiovascular Support forL-Carnitine
  9. Efficacy and tolerability of combined treatment with L-carnitine and simvastatin in lowering lipoprotein(a) serum levels in patients with type 2 diabetes mellitus.
    Solfrizzi V; Capurso C; Colacicco AM; D'Introno A; Fontana C; Capurso SA; Torres F; Gadaleta AM; Koverech A; Capurso A; Panza F · Atherosclerosis · 2007
    Randomized trial52 participantsCardiovascular Support forL-Carnitine