SuppHelper
search
Home›Supplements›Amino Acid›5-HTP›5-HTP Plus+ 200 mg NatureWise
Product Image

5-HTP Plus+ 200 mg

NatureWise

4.4
★ ★ ★ ★ ★
(5151 ratings)
5-HTP 200 mg
Product Image
Score 88

NatureWise 5-HTP Plus+ offers a potent 200mg dose with essential B6 for enhanced serotonin conversion, making it a strong choice for comprehensive mood and sleep support.

Quantity: 30 Capsule(s) • (30 servings)
Goals:
flag Mood Support
flag Sleep Support
flag Weight Loss
flag Stress Relief

leaderboard Score 88

NatureWise 5-HTP Plus+ offers a potent 200mg dose with essential B6 for enhanced serotonin conversion, making it a strong choice for comprehensive mood and sleep support.

insightsAnalysis

NatureWise 5-HTP Plus+ delivers a high 200mg dose of 5-HTP, which is an advanced dosage for individuals seeking strong support for mood, stress, and sleep. A key advantage of this product is the inclusion of 5mg of Vitamin B6 (as Pyridoxal 5-Phosphate, P-5-P), the active coenzyme form of B6. B6 is essential for the conversion of 5-HTP to serotonin, making this formulation potentially more effective than standalone 5-HTP products. While its price per serving is on the higher end compared to basic options, the combination of a high dose and the crucial cofactor contributes significantly to its overall efficacy and value for those needing comprehensive support.
thumb_upPros
  • High 200mg dosage provides strong support for mood, stress, and sleep.
  • Includes Vitamin B6 (P-5-P), a crucial cofactor for 5-HTP conversion, enhancing effectiveness.
  • NatureWise is a reputable brand known for quality supplements.
thumb_downCons
  • Higher price per serving compared to many other 5-HTP products.
  • Does not include Vitamin C, another potential cofactor for serotonin synthesis.
warningWarnings
  • 5-HTP should not be taken with antidepressant medications (SSRIs, MAOIs) or other serotonin-modulating drugs due to the risk of serotonin syndrome.
  • Consult a healthcare professional before use, especially if pregnant, nursing, or taking other medications.
  • May cause mild gastrointestinal discomfort (nausea, diarrhea) in some individuals, particularly at higher doses.
flagReport analysis
$13.11($0.43 per serving)
Amazon
$ 13.11
Vitacost
$ 13.99
Walmart
$ 13.99
iHerb
$ 14.57
flagReport prices

Ingredients

IngredientAmount per serving
Vitamin B6
5 mg
5-HTP
200 mg
grain_off Gluten Free person Adults 18–50 eco Vegan free_breakfast Dairy Free eco Vegetarian
flagReport overview

Categories

5-HTP 88
A top-tier option within the 5-HTP category, standing out due to its high potency and the inclusion of a vital cofactor, making it a highly effective and comprehensive choice.

Goals

flag Stress Relief 90
The potent 200mg dose, coupled with B6, offers robust support for stress management by optimizing serotonin synthesis, leading to better emotional resilience and stability.
flag Mood Support 90
The high 5-HTP dosage and the presence of the essential B6 cofactor make this an excellent choice for effectively boosting and stabilizing mood by maximizing serotonin production.
flag Sleep Support 85
The strong 5-HTP dose and B6 can significantly aid in melatonin production, contributing to improved sleep onset and quality, although a dedicated sleep blend might offer more direct sleep support for complex sleep issues.
inventory_2Recommended products
95 Value

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(5265 ratings)
At only 12 cents per serving for a 100mg dose with both B6 and C, it offers outstanding value by providing a complete and highly effective cofactor profile at a much lower cost per serving than the original.
Other sellers (3)
90 Value

5-HTP 100 mg

Doctor's Best
4.7
★★★★★
(12256 ratings)
A highly cost-effective option at 11 cents per serving for a 100mg dose, providing excellent pure 5-HTP value if the higher dose and B6 from the original aren't strictly necessary for the user's needs.
Other sellers (2)
85 Value

5-HTP with Vitamin B6 & Vitamin C

Lake Avenue Nutrition
4.7
★★★★★
(5077 ratings)
Offers 100mg 5-HTP with both B6 and C at 18 cents per serving, presenting a very good value for a comprehensive formulation, though less potent than the 200mg original.
Other sellers (0)
95 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(5265 ratings)
While a 100mg dose, it includes both B6 and C, providing a more comprehensive cofactor profile for optimal serotonin synthesis, potentially outperforming the original for those prioritizing full cofactor support over a higher single dose of 5-HTP.
Other sellers (3)
85 Performance

Advanced Sleep Melatonin + 5-HTP Time Release

Natrol
4.5
★★★★★
(8298 ratings)
Although a lower 5-HTP dose (50mg), its combination of time-release 5-HTP, melatonin, and B6 offers a more specialized and potentially superior solution specifically for complex sleep issues.
Other sellers (3)
70 Performance

5-HTP

Nature's Way
4.5
★★★★★
(829 ratings)
While at a higher price per serving, this option combines 100mg of 5-HTP with both B6 and C, which are crucial cofactors for enhanced absorption and conversion of 5-HTP.
Other sellers (2)
90 Budget

5-HTP 100 mg

Doctor's Best
4.7
★★★★★
(12256 ratings)
Offers a standard 100mg dose at a significantly lower 11 cents per serving, providing excellent value if a lower dose is sufficient for the user's needs.
Other sellers (2)
85 Budget

5-HTP 100 mg

NOW
4.7
★★★★★
(48226 ratings)
Provides a 100mg dose at 13 cents per serving from a highly reputable brand, offering a more economical option without sacrificing quality.
Other sellers (4)
80 Budget

5-HTP 100 mg Extra Strength

Swanson
4.8
★★★★★
(3247 ratings)
Delivers a 100mg dose at an incredibly low 11 cents per serving, representing a highly budget-friendly alternative for general 5-HTP support.
Other sellers (1)
95 Value

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(5265 ratings)
At only 12 cents per serving for a 100mg dose with both B6 and C, it offers outstanding value by providing a complete and highly effective cofactor profile at a much lower cost per serving than the original.
Other sellers (3)
90 Value

5-HTP 100 mg

Doctor's Best
4.7
★★★★★
(12256 ratings)
A highly cost-effective option at 11 cents per serving for a 100mg dose, providing excellent pure 5-HTP value if the higher dose and B6 from the original aren't strictly necessary for the user's needs.
Other sellers (2)
85 Value

5-HTP with Vitamin B6 & Vitamin C

Lake Avenue Nutrition
4.7
★★★★★
(5077 ratings)
Offers 100mg 5-HTP with both B6 and C at 18 cents per serving, presenting a very good value for a comprehensive formulation, though less potent than the 200mg original.
Other sellers (0)
95 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(5265 ratings)
While a 100mg dose, it includes both B6 and C, providing a more comprehensive cofactor profile for optimal serotonin synthesis, potentially outperforming the original for those prioritizing full cofactor support over a higher single dose of 5-HTP.
Other sellers (3)
85 Performance

Advanced Sleep Melatonin + 5-HTP Time Release

Natrol
4.5
★★★★★
(8298 ratings)
Although a lower 5-HTP dose (50mg), its combination of time-release 5-HTP, melatonin, and B6 offers a more specialized and potentially superior solution specifically for complex sleep issues.
Other sellers (3)
70 Performance

5-HTP

Nature's Way
4.5
★★★★★
(829 ratings)
While at a higher price per serving, this option combines 100mg of 5-HTP with both B6 and C, which are crucial cofactors for enhanced absorption and conversion of 5-HTP.
Other sellers (2)
flagReport alternatives

SuppHelper

Compare supplements smarter. Science-backed, user-rated, updated daily.

© 2025 SuppHelper. All rights reserved.

Explore

  • Compare Supplements
  • Health Goals
  • Stacks

Legal

  • Privacy Policy
  • Terms of Use
  • Medical Disclaimer

Stay in the Loop