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Adrenal Support

Vital Nutrients
4.7
★ ★ ★ ★ ★
(216 ratings)
Eleuthero 200 mg
Vitamin B5 100 mg
Cordyceps 100 mg
Ashwagandha 200 mg
Product Image
Score69
A larger-supply adaptogen and bovine glandular blend with clear dosing. Specialized animal ingredients and several interaction concerns remain important drawbacks.
How scoring works
Quantity:120 Capsule(s) • (60 servings)
Goals:
Cognitive Support

Score 69

A larger-supply adaptogen and bovine glandular blend with clear dosing. Specialized animal ingredients and several interaction concerns remain important drawbacks.
How scoring works

Also available as

1 option
60 servings Ashwagandha 200 mg, B5 100 mg +2 more • 60 Capsule(s) • 30 servings $31.99 ($1.06 per serving)
$57.99($0.96 per serving)
Vitacost
$ 57.99
iHerb
$ 57.99
Vitacost
$ 57.99
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Analysis

Eleuthero, ashwagandha, and B5 provide the clearest stress-and-energy support. Cordyceps is standardized according to the supplied analysis but remains a small secondary amount.

Bovine adrenal and adrenal cortex define this as a specialized glandular product rather than a general cognitive supplement. Its relevance to focus is indirect and depends on the user's actual nutritional need.

The 60-serving bottle improves convenience over the smaller version. Even so, the serving remains costly and the caution profile limits casual use.

Who is it for
  • Adults seeking a longer supply of an adaptogen-glandular formula
  • Non-vegetarian users
  • People targeting stress-oriented support
Best for
  • Eleuthero and ashwagandha combination use
  • Vitamin B5 supplementation
  • Longer-term glandular routines

Pros

  • Substantial B5 amount
  • Useful eleuthero amount
  • Includes ashwagandha
  • Sixty-serving supply

Cons

  • Contains bovine adrenal tissues
  • Cordyceps amount is low
  • Indirect cognitive relevance
  • Serving cost remains high

Warnings

  • Ashwagandha warrants caution during pregnancy and with thyroid or liver concerns
  • Eleuthero may affect blood pressure or stimulant medicines
  • Bovine glandular ingredients are unsuitable for vegetarians and may conflict with personal dietary restrictions

Nutrient quality

75 High impact

Eleuthero and pantothenic acid provide the strongest quality and dose support. Modest adaptogen doses and incompletely characterized bovine glandular ingredients limit confidence.

Ingredient transparency

74 High impact

All listed actives have specific amounts without a proprietary blend. Extract markers, glandular sourcing details, directions, and non-active capsule ingredients remain incomplete.

Customer satisfaction

68 High impact

The supplied satisfaction metric is strong and response volume is substantial. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

56 Moderate impact

A coherent adaptogen-and-glandular formula partly supports the cost. The larger package improves value, though incomplete standardization keeps it weakly competitive.

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Goals

Cognitive Support
Cognitive Support
Impact
High effect
C Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Ashwagandha · 200 mg

Adrenal Support combines 200 mg eleuthero with 200 mg ashwagandha and may support stress-related fatigue, but it does not directly target memory or cholinergic signaling.

Customer feedback averages 4.70 from 205 reviews; The multi-ingredient label and possible sedative, stimulant, or medication interactions deserve review.

Study evidence
Ashwagandha Supportive 17 studies
Eleuthero No effect 1 study

Ingredients

IngredientAmount per serving
Pantothenic Acid (Calcium Pantothenate)
 100 mg
Bovine Whole Adrenal
300 mg
Bovine Adrenal Cortex
150 mg
Eleuthero root extract
200 mg
Ashwagandha root extract
200 mg
Cordyceps sinensis mycelium extract
100 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Eleuthero · 200 mg OverallScore76
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The 200 mg Eleuthero root extract is standardized to 0.8% eleutherosides and transparently dosed. The larger package lowers the serving cost to $0.96, but it remains above the rubric's highest price band and limits overall collection value.

View ingredientView products
Vitamin B5 (Calcium Pantothenate) · 100 mg OverallScore72
A Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The 120-capsule Vital Nutrients Adrenal Support supplies 100 mg of calcium pantothenate, uses minimal excipients, and has 205 reviews averaging 4.70. Independent testing and clear disclosure support quality, while the $0.96 serving price equals $4.80 per 500 mg of B5.

View ingredientView products
Cordyceps · 100 mg OverallScore53
C Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Adrenal Support provides 100 mg Cordyceps sinensis mycelium extract and has a 4.70 average from 205 reviews. Independent testing and adenosine standardization support quality confidence, while the small dose limits its role as a primary cordyceps supplement.

View ingredientView products
Loading alternative details
81 Performance

Adrenal Serenity

Natural Factors Stress-Relax
<p>Sensoril ashwagandha, eleuthero, lavender, and rhodiola offer a concise, well-characterized plant-based stress formula. It avoids bovine glandular ingredients and improves cognitive alignment, though some extract and inactive-ingredient details are missing.</p>
81 Performance

AdrenaSense

Natural Factors WS WomenSense
<p>Marker-identified rhodiola, eleuthero, schisandra, and ashwagandha provide clear stress-resilience support without glandular tissues. Cordyceps and pantothenic acid are omitted, but the focused formula is easier to assess.</p>
73 Performance

HPA Adapt

Integrative Therapeutics
<p>Substantial Sensoril, rhodiola, eleuthero, holy basil, and branded maca create a deep stress and stamina formula without animal-derived tissues. Marker detail remains incomplete and the serving cost is high.</p>
79 Budget

Dual Ginseng Plus

Swanson Superior Herbs
<p>Standardized ginseng and eleuthero provide a far lower-cost adaptogen base without bovine glandular tissues. Plain ashwagandha and incomplete marker detail limit quality, while cordyceps and pantothenic acid are absent.</p>
67 Budget

Adrenal Optimizer

Jarrow Formulas
<p>Ashwagandha, rhodiola, eleuthero, schisandra, and supportive herbs create a much cheaper plant-only stress and energy blend. Weak standardization, modest doses, high pantothenic acid, and licorice-related concerns remain drawbacks.</p>
62 Budget

Yohimbe-Plus Maximum Enhancement

Irwin Naturals
<p>Ashwagandha and eleuthero provide lower-cost adaptogen coverage, but the formula is oriented toward sexual performance rather than cognitive or stress support. Undisclosed yohimbine yield may raise heart rate or blood pressure, making it a poor fit for many users.</p>
68 Value

Adrenal Support

Vital Nutrients
<p>The smaller bottle uses the identical formula and may suit someone trialing it before committing to a larger supply. It costs more per serving and retains every limitation, so it is not a genuine value improvement.</p>
72 Value

CalmEssence

Pure Essence
<p>Ashwagandha and theanine anchor a coherent calming blend with supportive adaptogens and no glandular ingredients. Extract standardization is limited and serving cost is slightly higher, so the trade-off is formula preference rather than economy.</p>
68 Value

Stress Remedy

Pure Synergy
<p>A high ashwagandha amount leads a broad plant-only stress blend with useful calming support. Many secondary extracts are lightly dosed or unstandardized, and the high serving cost does not establish better value.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsCognitive Support forAshwagandha
  2. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsCognitive Support forAshwagandha
  3. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support forAshwagandha
  4. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support forAshwagandha
  5. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsCognitive Support forAshwagandha
  6. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsCognitive Support forEleuthero