One Daily Essential
21st Century
One Daily Essential
4.7
★ ★ ★ ★ ★
(2955 ratings)
Niacin 20 mg
Score 80.0
A very affordable 'one daily' multivitamin providing a gentle Niacinamide dose for general energy and metabolic support, but not for targeted high-dose niacin benefits.
Quantity: 100 Tablet(s)Servings size: 1 Tablet(s) (100 servings)
Selected goals:
Other goals:
Heart Health
Skin Health
Energy
Metabolism Boost
leaderboard Score 80.0
A very affordable 'one daily' multivitamin providing a gentle Niacinamide dose for general energy and metabolic support, but not for targeted high-dose niacin benefits.
insights Analysis
The 21st Century One Daily Essential provides 20mg of Niacin in its niacinamide form, designed as a component of a comprehensive daily nutritional intake. This product stands out for its extreme affordability and convenience as a 'one daily' supplement, making it an accessible option for general health maintenance. The choice of niacinamide ensures that users receive the benefits of Niacin without experiencing the uncomfortable 'flush' commonly associated with nicotinic acid. However, for individuals seeking more pronounced effects for specific health goals like advanced heart health support or significant dermatological improvements, the low dose of Niacin in this multivitamin format would likely be insufficient, as its primary purpose is general dietary support.
- Niacin in niacinamide form (20mg), avoiding the flush.
- Very affordable price per serving.
- Suitable for general daily nutritional support as part of a 'One Daily' formula.
- Niacin dose is too low for specific therapeutic effects on heart health.
- Not optimized for significant skin improvements often seen with higher niacinamide doses.
- As a multivitamin, the focus on Niacin is minimal, not a dedicated Niacin product.
$3.02($0.03 per serving)
 Pure Formulas | $ 3.02 | |
 iHerb | $ 5.99 |
bolt Effectiveness for goals
Niacin is known as one of the most effective agents for increasing high-density lipoprotein (HDL) cholesterol levels. It can significantly raise HDL, which is often considered beneficial for cardiovascular health. However, studies have shown that this increase in HDL does not always translate to a reduction in cardiovascular events.
While Niacin can contribute to lowering LDL cholesterol, its primary effect on lipids is typically a more significant reduction in triglycerides and an increase in HDL cholesterol. For LDL reduction, it is generally considered less potent than statins and often used in conjunction with other lipid-lowering therapies if prescribed.
Yes, Niacin is highly effective at reducing elevated triglyceride levels. It achieves this by decreasing the liver's production of very low-density lipoprotein (VLDL), which is a precursor to triglycerides and LDL cholesterol. This makes it a common consideration for individuals with hypertriglyceridemia.
Niacin, also known as vitamin B3, is primarily recognized for its role in preventing and treating pellagra, a deficiency disease. In supplement form, it has been extensively studied for its effects on cholesterol and triglyceride levels. Its physiological functions include energy metabolism and DNA repair.
Niacin can be used in combination with statins to further improve lipid profiles, particularly to increase HDL and lower triglycerides. However, some studies have shown that adding Niacin to statin therapy does not consistently provide additional cardiovascular benefits and may increase the risk of side effects such as myopathy (muscle pain) when taken with certain statins. Medical supervision is essential for this combination.
schedule Dosage, timing & forms
Nicotinic acid is the form most commonly associated with the 'niacin flush' and is often used at higher doses for specific health support under medical supervision. Niacinamide (nicotinamide) generally does not cause flushing and is often preferred for general vitamin B3 supplementation, though it has different metabolic effects compared to nicotinic acid. Their applications can differ significantly.
'Flush-free' niacin, often inositol hexanicotinate, is a form where niacin is chemically bound to inositol, a sugar-like compound. This bond leads to a slow, gradual release of niacin in the body, significantly reducing or eliminating the rapid vasodilation that causes the common flushing sensation. It's often chosen by individuals sensitive to the flush.
To minimize the niacin flush from immediate-release nicotinic acid, individuals can start with a very low dose and gradually increase it over time. Taking it with a non-fatty meal, avoiding hot beverages or alcohol around the time of dosing, and potentially taking aspirin 30 minutes beforehand (if medically appropriate and advised) can also help. Slow and steady increases in dosage are key.
Immediate-release niacin (nicotinic acid) is absorbed quickly, leading to a rapid peak effect and often a pronounced, but temporary, flush. Extended-release forms are designed to release niacin slowly over several hours, which can help reduce the intensity and duration of the flush and may allow for less frequent dosing. The slower release aims to improve tolerance.
Niacin is available in several forms, including nicotinic acid (immediate-release and extended-release), niacinamide (nicotinamide), and inositol hexanicotinate (often marketed as 'no-flush' niacin). Each form has distinct properties and effects within the body. The choice of form can influence how it is absorbed and its potential side effects.
health_and_safety Safety & interactions
The niacin flush is a common side effect characterized by redness, itching, warmth, and tingling, primarily on the face, neck, and chest. It is caused by the release of prostaglandins, which dilate blood vessels. Taking niacin with food, starting with a low dose and gradually increasing it, or taking a low-dose aspirin before niacin may help reduce the flush.
High doses of niacin, particularly sustained-release forms, have been associated with elevated liver enzymes and, in rare cases, liver toxicity. Regular monitoring of liver function by a healthcare professional is often recommended when taking high-dose niacin. Individuals with pre-existing liver conditions should avoid niacin unless specifically advised by a doctor.
Yes, niacin can interact with several medications. It may enhance the effects of blood pressure-lowering drugs, potentially causing hypotension, and can increase the risk of myopathy when taken with statins. Niacin might also interact with blood thinners, antidiabetic medications, and gout medications. Consulting a healthcare provider about all current medications before starting niacin is important.
Individuals with active liver disease, severe hypotension, active peptic ulcer disease, or active bleeding should generally avoid niacin supplements. Those with a history of gout, diabetes, or gallbladder disease should also use niacin with caution and under medical supervision. Consultation with a healthcare provider is essential to determine suitability.
High doses of niacin, particularly nicotinic acid, can sometimes increase blood glucose levels. This effect is more pronounced in individuals with diabetes or prediabetes. People managing their blood sugar should monitor their levels closely if taking niacin and discuss its use with a healthcare provider.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin A | 900 mcg |
Vitamin C | 60 mg |
Vitamin D3 | 10 mcg |
Vitamin E | 13.5 mg |
Thiamine | 1.5 mg |
Riboflavin | 1.7 mg |
Niacin | 20 mg |
Vitamin B6 | 2 mg |
Folate | 667 mcg DFE |
Vitamin B12 | 6 mcg |
Pantothenic Acid | 10 mg |
Calcium | 93 mg |
Categories
Niacin 65.0
As a source of Niacin, this product offers a non-flushing form at a very accessible price point, but the low dosage means it acts more as a basic dietary supplement rather than a potent Niacin-focused product.
Goals
Energy 85.0
As part of a daily essential supplement, the Niacin, along with other vitamins present, contributes effectively to the metabolic processes required for converting food into energy, supporting overall vitality.
Metabolism Boost 85.0
Niacin plays a vital role as a coenzyme in metabolic pathways, and its inclusion in this daily essential product helps support efficient metabolism of macronutrients, contributing to general metabolic health.
Skin Health 60.0
Niacinamide at this dose provides basic support for skin health by contributing to overall nutritional needs, but it is not formulated to deliver the higher concentrations often found in supplements or topicals aimed at significant skin improvements.
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