SAMe 400 mg
Protocol For Life Balance
SAMe 400 mg
4.9
★ ★ ★ ★ ★
(46 ratings)
SAMe 400 mg
Score 70
A high-dose 400mg SAMe product from a reputable professional brand, offering good efficacy but at a higher price point than many market competitors and with limited online reviews.
Quantity: 60 Tablet(s) • (30 servings)
Goals: flag Joint Health flag Mood Support flag Detoxification flag Stress Relief
leaderboard Score 70
A high-dose 400mg SAMe product from a reputable professional brand, offering good efficacy but at a higher price point than many market competitors and with limited online reviews.
insights Analysis
Protocol For Life Balance is recognized as a professional-grade brand, often favored by practitioners for its stringent quality control and effective formulations, with this product providing a clinically relevant 400mg dose of SAMe per tablet. While the dosage aligns well with recommendations for mood and joint support, its price per serving of $1.09 remains considerably higher than many high-quality SAMe alternatives on the market. The relatively low number of consumer reviews (46) also provides less comprehensive public feedback compared to more widely reviewed products in the SAMe category.
- Provides a robust 400mg dose per serving, suitable for therapeutic use in mood and joint support.
- Sourced from a professional-grade brand known for quality and purity standards.
- Convenient 60-count bottle offers a good supply for consistent use.
- The price per serving ($1.09) is on the higher end compared to other quality 400mg SAMe supplements.
- Relatively low review count (46) offers less general consumer feedback on efficacy and satisfaction.
- Specific form of SAMe is not detailed beyond 'SAMe' in the ingredients list, although it is likely the stable disulfate tosylate form.
- Individuals with bipolar disorder should avoid SAMe as it can potentially induce manic episodes.
- SAMe can interact with antidepressant medications, increasing the risk of serotonin syndrome; consult a healthcare professional before combining.
- New users should consider starting with a lower dose (e.g., 200mg) to assess tolerance before increasing to 400mg.
$65.47($2.18 per serving)
 iHerb | $ 65.47 | |
 Pure Formulas | $ 72.00 |
Ingredients
| Ingredient | Amount per serving |
|---|---|
SAMe | 400 mg |
Categories
SAMe 75
This product delivers a well-dosed amount of SAMe from a trusted professional brand, making it a reliable choice within the SAMe supplement category. Its score reflects its strong dosage and brand quality, tempered slightly by its price point which, while offering better value than some premium brands, isn't the most competitive among all available alternatives.
Goals
A 400mg dose is a common and effective starting point for SAMe in supporting mood and combating depressive symptoms, aligning well with clinical research for neurotransmitter balance. This dosage is more likely to yield noticeable effects for many individuals compared to lower 200mg options, offering substantial support for emotional well-being.
The 400mg dosage serves as a good foundational amount for addressing joint discomfort and promoting cartilage health, with many studies supporting its role in osteoarthritis management. While some individuals with more significant joint issues may eventually benefit from higher daily doses, this product provides a solid therapeutic starting point.
SAMe at 400mg effectively contributes to essential liver detoxification pathways and bile production, which are crucial for optimal digestive function and overall metabolic health. This dosage provides significant support for liver health, a primary component of digestive well-being and nutrient processing.
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4.6
★★★★★
(265 ratings)
Offers a 400mg SAMe dose at a competitive price, providing good potency for the cost from a widely available and established brand.
60 Value
SAMe 400 mg
NOW
4.7
★★★★★
(959 ratings)
Provides a reliable 400mg SAMe dose from a trusted brand, offering a solid balance of quality and value for those seeking this potency.
55 Value
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Source Naturals
4.7
★★★★★
(191 ratings)
A higher 400mg SAMe dose option that balances potency with a reasonable price point, offering good overall value for individuals seeking a higher dosage.
98 Performance
SAMe 200 mg + Cofactors
Metabolic Maintenance
4.6
★★★★★
(30 ratings)
Offers comprehensive support with bioavailable cofactors, enhancing the overall efficacy and methylation benefits, even at a 200mg SAMe dose, making it superior for holistic support.
95 Performance
SAMe with Vitamins B-6 B-12 and 5-MTHF
Designs for Health
5.0
★★★★★
(11 ratings)
Provides high-quality SAMe with essential, active B vitamin cofactors for a more complete approach to mood and methylation, a step up in formulation.
68 Performance
SAMe (S-Adenosylmethionine)
Pure Encapsulations
4.5
★★★★★
(18 ratings)
While similar in dosage, Pure Encapsulations is renowned for its exceptional purity and quality standards, making it a preferred choice for those prioritizing brand integrity.