L-Tryptophan 500 mg
Advanced Nutrition by Zahler
L-Tryptophan 500 mg
4.6
★ ★ ★ ★ ★
(140 ratings)
Tryptophan 500 mg
Score 68.0
A 500mg L-Tryptophan capsule enhanced with Vitamin B3, offering improved conversion support, but at a slightly higher price point.
Quantity: 60 Capsule(s)Servings size: 1 Capsule(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 68.0
A 500mg L-Tryptophan capsule enhanced with Vitamin B3, offering improved conversion support, but at a slightly higher price point.
insights Analysis
Zahler's L-Tryptophan offers a 500mg dose per capsule, uniquely enhanced with 8.30mg of Vitamin B3. This addition is a strategic advantage, as B vitamins, particularly Niacin (B3), are crucial cofactors in the metabolic pathways that convert L-Tryptophan into serotonin and melatonin, potentially increasing the product's efficacy. While its price per serving is slightly higher than some basic L-Tryptophan options, the inclusion of Vitamin B3 adds value for consumers seeking optimized neurotransmitter support. The relatively lower review count compared to market leaders might reflect a smaller market presence rather than product quality.
- Contains Vitamin B3, a key cofactor for optimal L-Tryptophan conversion to serotonin and melatonin.
- Standard and effective 500mg L-Tryptophan dose.
- Convenient capsule form.
- Higher price per serving compared to many pure L-Tryptophan options, which might deter budget-conscious consumers.
- Lower number of reviews compared to leading alternatives.
- Individuals should be aware of the Niacin content if they are sensitive to B vitamins, although the dose is relatively small.
$19.47($0.32 per serving)
 Pure Formulas | $ 19.47 | |
 Vitacost | $ 20.89 | |
 iHerb | $ 22.64 |
bolt Effectiveness for goals
Tryptophan is an essential amino acid that serves as the sole precursor for the synthesis of serotonin in the body. After absorption, Tryptophan is converted to 5-hydroxytryptophan (5-HTP), which then converts to serotonin. This process is crucial for various physiological functions.
Tryptophan is an essential amino acid often supplemented to support the body's natural production of serotonin and melatonin. These compounds play roles in mood regulation, sleep cycles, and overall well-being. Its use is typically aimed at supporting these physiological processes.
L-Tryptophan is an essential amino acid, meaning the body cannot produce it and it must be obtained through diet. It serves as a precursor to serotonin, a neurotransmitter involved in mood regulation, and melatonin, a hormone that regulates sleep-wake cycles. Additionally, Tryptophan is involved in the synthesis of niacin (vitamin B3).
Some research suggests that Tryptophan may support sleep by increasing the production of serotonin, which is a precursor to melatonin. Melatonin is a hormone crucial for regulating the sleep-wake cycle. While findings are mixed, some individuals report benefits in sleep latency and quality.
L-Tryptophan is converted into 5-hydroxytryptophan (5-HTP), which then becomes serotonin, and subsequently melatonin in the pineal gland. Melatonin is a key hormone that helps regulate the body's circadian rhythm and promote sleep. By providing the building blocks for melatonin, Tryptophan may contribute to sleep onset and quality.
schedule Dosage, timing & forms
L-Tryptophan dosages are generally higher (e.g., 500-2000mg) compared to 5-HTP (e.g., 50-300mg), as 5-HTP is a more direct precursor to serotonin. Both are often taken before bed for sleep or split through the day for mood support. Their absorption and potential effects can differ due to their metabolic pathways.
Typical dosages for L-Tryptophan can range from 500 mg to 2000 mg per day, often split into multiple doses. The appropriate amount can depend on individual needs and the desired effect. It's generally advisable to start with a lower dose and adjust as needed, preferably under guidance.
Typical dosages for L-Tryptophan can vary based on individual needs and the intended use. For sleep support, dosages often range from 500 mg to 2000 mg taken before bedtime. For mood support, lower doses may be taken throughout the day. It's advisable to start with a lower dose and adjust as needed, preferably under guidance.
To optimize absorption and reduce competition with other amino acids, L-Tryptophan is often recommended to be taken on an empty stomach. Alternatively, taking it with a carbohydrate-rich, protein-low snack can enhance its transport into the brain. Taking it with protein-rich meals can hinder its effectiveness.
For sleep support, L-Tryptophan is often recommended to be taken 30-60 minutes before bedtime. For other purposes, it might be taken throughout the day, sometimes between meals to aid absorption. Individual responses can vary.
health_and_safety Safety & interactions
Combining L-tryptophan with antidepressant medications, particularly SSRIs, MAOIs, or tricyclics, can significantly increase serotonin levels, potentially leading to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before combining these substances. Always seek medical advice regarding supplement and medication interactions.
Yes, L-Tryptophan can interact significantly with medications that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and MAO inhibitors. Combining Tryptophan with these drugs can potentially lead to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before taking L-Tryptophan if you are on any such medications.
Common side effects, especially at higher doses, can include mild gastrointestinal issues such as nausea, heartburn, stomach pain, and loss of appetite. Other potential effects might include drowsiness, dizziness, and dry mouth. It's generally well-tolerated when taken appropriately.
Yes, supplements that also influence serotonin levels, such as 5-HTP and St. John's Wort, should generally not be combined with L-tryptophan. This combination could also elevate the risk of serotonin syndrome. Always consult a healthcare provider for personalized advice on supplement stacking.
Individuals taking antidepressant medications (SSRIs, SNRIs, MAOIs), certain pain medications, or other drugs that affect serotonin should generally avoid L-Tryptophan due to the risk of serotonin syndrome. Pregnant or breastfeeding women, and those with pre-existing liver or kidney conditions, should also consult a healthcare provider before use. People with Eosinophilia-Myalgia Syndrome (EMS) history should also exercise caution.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B3 | 8.3 mg |
L-Tryptophan | 500 mg |
Categories
Tryptophan 68.0
While it stands out for including a valuable cofactor, its value proposition is diminished by a higher price when compared to more cost-effective pure L-Tryptophan options or comprehensive blends.
Goals
Mood Support 75.0
The 500mg L-Tryptophan combined with Vitamin B3 offers enhanced support for serotonin production, which is crucial for mood stability.
Stress Relief 75.0
The synergistic effect of L-Tryptophan and Vitamin B3 can more effectively support neurotransmitter balance, contributing to stress reduction.
Sleep Support 75.0
The presence of Vitamin B3 can facilitate the conversion of L-Tryptophan to melatonin, potentially leading to more effective sleep support.
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4.5
★★★★★
(1931 ratings)
Delivers the same 500mg L-Tryptophan dosage at a significantly reduced price per serving and in a larger bottle (90 servings vs 60), making it a much more budget-friendly option for ongoing use.
100 Performance
L-Tryptophan 1000 mg
AN Amazing Nutrition Amazing Formulas
4.5
★★★★★
(2545 ratings)
Offers a higher, more potent dose (1000mg vs 500mg) of L-Tryptophan, which can be more effective for some individuals seeking mood and sleep support. It is highly regarded by users, evidenced by its extensive positive reviews, and provides superior value.
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(1307 ratings)
This product delivers a higher L-Tryptophan dose (1000mg) and includes synergistic ingredients like L-Lysine and Niacin, which can enhance the conversion of tryptophan and provide more comprehensive mood and sleep support. It comes from a reputable brand with strong customer satisfaction.
95 Performance
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Utilizes the 'TryptoPure' form of L-Tryptophan, which is often associated with higher quality and purity. It has garnered significantly more positive reviews online, reflecting greater consumer trust and reported efficacy compared to the original product.