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Femesse

Arthur Andrew Medical
4.3
★ ★ ★ ★ ★
(831 ratings)
Selenium 120 mcg
Vitamin B6 40 mg
Vitamin E 40 IU
Folate 100 mcg
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Score79

A botanical-heavy formula for women that combines Vitamin B6 and selenium to support hormonal and metabolic balance.

How scoring works
Quantity:240 Capsule(s) • (60 servings)
Goals:
General Health
Immunity
Metabolism Boost

Score 79

A botanical-heavy formula for women that combines Vitamin B6 and selenium to support hormonal and metabolic balance.

How scoring works
$34.99($0.58 per serving)
iHerb
$ 34.99
Pure Formulas
$ 34.99
Amazon
$ 34.99
Vitacost
$ 37.49
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Analysis

I like that this formula includes 120mcg of selenomethionine, which is a highly absorbable form of selenium that supports your natural antioxidant enzymes. It provides 40mg of Vitamin B6 to help with metabolic rate and hormone regulation, alongside a very large 1.94 gram proprietary blend. This mix is designed to support healthy tissue protection and general metabolic function in women.

However, the serving size is 4 capsules per day, which might be a lot for some users. It uses synthetic folic acid and zinc sulfate, which are less expensive forms of these nutrients and may not be as absorbable as others. While it supports several goals, it is a very niche product that is best used for its specific botanical benefits.

Pros

  • Significant dose of bioavailable selenium
  • Includes a very large botanical blend
  • Focuses on antioxidant tissue protection
  • High-potency Vitamin B6

Cons

  • Requires taking 4 capsules daily
  • Uses synthetic folic acid
  • Uses zinc sulfate which can be stomach-irritating

Warnings

  • Zinc sulfate may cause mild nausea if taken on an empty stomach
  • Not for use by children or pregnant women

Nutrient quality

81 Highest impact

The use of natural d-alpha vitamin E and chelated selenium ensures good bioavailability for antioxidant support. However, the core nutrients are provided at maintenance levels rather than therapeutic potency.

Ingredient transparency

73 High impact

The label discloses the amounts for primary vitamins and minerals but obscures the botanical details within large proprietary blends. This reduces the consumer's ability to judge the potency of the secondary ingredients.

Customer satisfaction

87 Highest impact

A moderate rating over hundreds of reviews suggests that users find value in the formula but experience mixed results compared to high-potency products. Consumer trust appears stable but not exceptional in the category.

Value for money

75 High impact

At 58 cents per serving, this product is relatively expensive for its primary vitamin and mineral content. The price is likely driven by the botanical blends, making it a specialized choice for specific user needs.

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Goals

Impact
High effect
B+ Goal FitB Strength of SupportB CoverageB Formula Quality

Vitamin B6, selenium, and folic acid are paired with a multi-botanical blend to support daily vitality and resilience. This formulation targets antioxidant status and metabolic pathways through a diverse ingredient profile.

Providing 120 mcg of selenomethionine ensures meaningful daily mineral support for systemic health. While the mineral and vitamin forms are effective, the use of synthetic folic acid is less bioavailable than methylated alternatives.

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Impact
High effect
B+ Goal FitC- Strength of SupportB+ CoverageB Formula Quality

Specialized formula includes a variety of vitamins and minerals to maintain baseline nutritional status and antioxidant defenses. This approach assists in providing the necessary cofactors for healthy immune cell activity and resilience.

Selenium and vitamin E provide foundational antioxidant support within this complex blend. While these nutrients are present at meaningful daily doses, the very low 8mg dose of zinc sulfate may be less effective and more irritating than organic forms.

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Impact
High effect
B- Goal FitC+ Strength of SupportC+ CoverageB- Formula Quality

Selenium and zinc act as necessary cofactors for thyroid hormone status, which regulates energy expenditure. Pyridoxine appears to support protein and glycogen metabolism, aiding in the body's conversion of food into fuel.

Various botanical extracts are included within a large proprietary blend to support overall vitality. These ingredients appear well suited for maintaining foundational metabolic support through mineral and vitamin pathways.

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Impact
Moderate effect
C+ Goal FitC Strength of SupportC- CoverageB- Formula Quality

Selenomethionine and vitamin E work together to protect liver cells from oxidative byproducts of Phase I detoxification. The 40 mg dose of vitamin B6 provides therapeutic support for transsulfuration pathways, aiding in glutathione production.

Folate as folic acid is included at a low level, which may limit its effectiveness for methylation-driven clearance. This specialized botanical blend offers focused antioxidant support, though it lacks breadth across core mineral and biliary pathways.

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Impact
Moderate effect
C- Goal FitC- Strength of SupportC- CoverageB- Formula Quality

This specialized formula supports the underlying nutritional matrix of nails with foundational minerals like zinc and selenium. It includes 100 mg of L-methionine, a sulfur-containing amino acid that serves as a precursor for building the keratin plate.

The formula utilizes a large proprietary blend of botanicals that provides antioxidant protection for the nail bed and surrounding tissues. While it addresses keratin building blocks, the absence of biotin and structural building blocks like silicon limits its effectiveness for structural repair.

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Impact
Moderate effect
C- Goal FitD Strength of SupportD CoverageD+ Formula Quality

Utilizing organic selenomethionine and vitamin B6 may contribute to managing oxidative stress and supporting homocysteine metabolism. These ingredients appear well aligned with foundational cardiovascular health, although some forms used are less bioavailable.

The inclusion of folic acid at a low dose limits the therapeutic impact on homocysteine regulation compared to active methylfolate. This formula provides secondary support through botanical blends but lacks the focused potency of primary heart nutrients.

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Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopherol Succinate)
40 IU
Vitamin B6 (Pyridoxine Hydrochloride)
40 mg
Folate (Folic Acid)
100 mcg
Zinc (Zinc Sulfate)
8 mg
Selenium (Selenomethionine)
120 mcg
Femesse Proprietary Blend
1940 mg
Proprietary Blend
260 mg
Gluten Free Vegan Dairy Free Women Women 18–50 Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
This specialized formula includes organic selenomethionine for optimal absorption as part of its antioxidant profile. It provides a safe maintenance dose, though it is not the most cost-efficient way to obtain the mineral.
D+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD+ Value
This specialized botanical formula provides 40mg of Vitamin B6 in synthetic form. While the B6 dose is safe and therapeutic, the requirement of four capsules per day and the less active B6 form are drawbacks.
D Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value
This specialized supplement provides a modest maintenance dose of high-quality natural Vitamin E. While the form is excellent, the dose is lower than what is typically found in dedicated antioxidant products.
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