Melatonin Advanced Sleep 10 mg Time Release
Natrol
Melatonin Advanced Sleep 10 mg Time Release
4.5
★ ★ ★ ★ ★
(844 ratings)
Vitamin B6 10 mg
Melatonin 10 mg
Score 80.0
A potent 10mg time-release melatonin from Natrol for strong, sustained sleep, with added B6.
Quantity: 75 Tablet(s)Servings size: 1 Tablet(s) (75 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Stress Relief
leaderboard Score 80.0
A potent 10mg time-release melatonin from Natrol for strong, sustained sleep, with added B6.
Quantity: 240, Dose: 3mgQuantity: 60, Dose: 5mgQuantity: 60, Dose: 3mgQuantity: 90, Dose: 1mgQuantity: 180, Dose: 1mgQuantity: 120, Dose: 3mgQuantity: 100, Dose: 5mgQuantity: 60, Dose: 10mgQuantity: 100, Dose: 10mg
insights Analysis
Natrol Melatonin Advanced Sleep 10 mg Time Release is a strong formulation designed for individuals with persistent and severe sleep disturbances. The 10mg dose provides a high level of melatonin to facilitate sleep onset, while the time-release mechanism ensures a sustained effect throughout the night, mimicking the body's natural melatonin production curve for prolonged sleep maintenance. The inclusion of 10mg of Vitamin B6 (Pyridoxine Hydrochloride) offers minor supporting benefits for nervous system health and neurotransmitter function, but the core efficacy of the product lies in its high-potency melatonin. Its lower review count compared to other established Natrol melatonin products might suggest it's a newer variant or has a more niche audience.
- High 10mg dose provides strong efficacy for significant sleep onset and maintenance issues.
- Time-release mechanism ensures sustained sleep throughout the night, preventing mid-night awakenings.
- From a reputable brand known for quality sleep supplements.
- Includes Vitamin B6, which supports nervous system function and serotonin production.
- The 10mg dose may be excessive for many individuals and could lead to morning grogginess or dependence.
- Relatively high price per serving compared to lower-dose or non-time-release melatonin options.
- General health claims like 'Energy' or 'Anti-Aging' are indirect and not the primary focus or strength of the product's ingredients.
$8.96($0.11 per serving)
 Walmart | $ 8.96 |
bolt Effectiveness for goals
Melatonin is commonly used to help with sleep difficulties, particularly for primary insomnia or when the body's internal clock is disrupted. It may help reduce the time it takes to fall asleep and can improve overall sleep quality for some individuals. Its effectiveness can vary depending on the specific sleep issue.
Pyridoxine, the active form of Vitamin B6, is often recommended and can be effective for reducing nausea and vomiting during pregnancy, commonly known as morning sickness. It is considered a first-line treatment option, often combined with doxylamine. Its effectiveness has been demonstrated in multiple clinical studies.
Vitamin B6 plays a crucial role in nerve function and the production of neurotransmitters. It is essential for maintaining a healthy nervous system and can be used to manage certain types of neuropathy, particularly those caused by B6 deficiency. Adequate B6 intake supports overall neurological health.
Melatonin has been shown to be effective in reducing jet lag symptoms, especially when traveling across multiple time zones. It can help resynchronize the body's circadian rhythm to the new time zone. Timing of administration relative to the new time zone is crucial for optimal effect.
Vitamin B6 is involved in the synthesis of neurotransmitters like serotonin and dopamine, which influence mood. Some research suggests a potential link between B6 levels and mood regulation, but it is not a primary treatment for mood disorders. Its effectiveness for mood is often considered in the context of overall nutritional status.
schedule Dosage, timing & forms
Melatonin is generally recommended to be taken about 30 minutes to 2 hours before your intended bedtime. This allows time for the supplement to be absorbed and begin its effect. Consistency in timing is often suggested for best results.
Yes, excessive intake of Vitamin B6, particularly from supplements, can lead to nerve damage, a condition known as peripheral neuropathy. This risk increases with prolonged use of doses significantly above the tolerable upper intake level (UL) of 100 mg per day for adults. Symptoms can include numbness, tingling, and pain in the extremities.
Typical dosages for melatonin in adults generally range from 0.5 mg to 5 mg, though some products may offer higher amounts. It is often recommended to start with the lowest effective dose. Dosages can vary based on individual needs and the specific reason for use.
For adults, the recommended daily allowance (RDA) for Vitamin B6 is 1.3-1.7 mg, but supplements often contain higher amounts, such as 10-100 mg. It is important not to exceed the tolerable upper intake level (UL) of 100 mg per day for adults to avoid potential side effects. Higher doses are sometimes used under professional guidance for specific conditions.
While short-term use of melatonin at common dosages is generally considered safe, the long-term safety of high doses has not been extensively studied. Prolonged use, especially at higher amounts, may potentially disrupt the body's natural melatonin production or lead to side effects. It is best to use the lowest effective dose and discuss long-term use with a healthcare professional.
health_and_safety Safety & interactions
Melatonin can interact with several medications, including anticoagulants, immunosuppressants, diabetes medications, and some antidepressants. It may also increase the effects of sedatives, potentially causing excessive drowsiness. Always discuss supplement use with a healthcare provider, especially if taking other medications.
Common side effects of melatonin can include daytime drowsiness, dizziness, headache, and nausea. Some individuals may also experience vivid dreams or temporary feelings of depression. These effects are generally mild and temporary.
The long-term safety of melatonin use is not fully established. While generally considered safe for short-term use, some studies suggest potential effects on the body's natural melatonin production or hormone balance with prolonged use. It is advisable to consult a healthcare professional regarding long-term use.
At recommended doses, Vitamin B6 is generally considered safe. However, high doses, typically exceeding 200 mg/day over long periods, can lead to nerve damage. Symptoms may include numbness, tingling, and difficulty walking.
Due to limited research and safety data, melatonin is generally not recommended for use during pregnancy or breastfeeding. The potential effects on fetal development or infant health are not well understood. It is best to consult a healthcare professional before considering its use in these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 10 mg |
Calcium | 23 mg |
Melatonin | 10 mg |
Categories
Melatonin 90.0
The 10mg dose with time-release is a powerful formulation for comprehensive sleep support, effectively addressing both sleep onset and maintenance, especially for severe cases.
Vitamin B6 50.0
The 10mg Pyridoxine Hydrochloride is a common dosage for general B6 support, contributing to nerve function, but not a primary high-potency source.
Goals
Sleep Support 90.0
The 10mg time-release dose is highly effective for individuals with persistent and severe sleep difficulties, ensuring both sleep onset and prolonged sleep.
Stress Relief 65.0
Superior sleep profoundly alleviates chronic stress, and the B6 content also plays a supportive role in neurological well-being.
Mood Support 65.0
Consistent, high-quality sleep is crucial for emotional stability, with B6 contributing to healthy neurotransmitter function.
Recommended Alternatives
88 Value 
Melatonin 5 mg
Spring Valley
4.6
★★★★★
(3117 ratings)
Provides a robust 5mg melatonin dose at a very low price per serving, offering excellent potency and value for those seeking a cost-effective sleep aid without time-release.
85 Value 
Melatonin 3 mg
NOW
4.8
★★★★★
(4544 ratings)
Delivers an effective 3mg dose with a high number of servings (180) at a very low price per serving, offering great long-term value for consistent sleep support.
75 Value 
Melatonin 3 mg
21st Century
4.8
★★★★★
(14990 ratings)
Another strong value option, providing a 3mg dose at a very low price per serving and a substantial quantity (200 servings), ideal for consistent, budget-friendly sleep aid.
98 Performance 
Insomnitol
Designs for Health
4.6
★★★★★
(32 ratings)
A premium, multi-ingredient formula that likely targets various sleep mechanisms, offering a more comprehensive and potentially more effective solution for persistent sleep issues.
95 Performance 
Ortho Sleep
AOR Advanced Orthomolecular Research Advanced
4.1
★★★★★
(129 ratings)
Another comprehensive sleep support product, designed to provide broader and deeper sleep benefits through a synergistic blend of ingredients beyond just melatonin.
92 Performance 
Power to Sleep PM
Irwin Naturals
4.3
★★★★★
(2630 ratings)
This product is designed specifically as a 'Power to Sleep PM' blend, indicating it contains a combination of sleep-promoting ingredients for a more enhanced and holistic sleep experience.
90 Budget 
Melatonin 5 mg Time Release
Natrol
4.7
★★★★★
(78122 ratings)
Provides a robust 5mg time-release dose from the same brand, which is often sufficient for many users, at a lower price per serving.
80 Budget 
Melatonin 5 mg
NOW
4.7
★★★★★
(11948 ratings)
Offers a significant 5mg dose at a much lower price per serving, providing potent sleep support at a budget-friendly rate, though it lacks time-release.
78 Budget 
Melatonin 3 mg
Nature Made
4.7
★★★★★
(18332 ratings)
A very cost-effective option for a standard 3mg melatonin dose, significantly cheaper per serving for those who don't require 10mg or time-release.
88 Value
Melatonin 5 mg
Spring Valley
4.6
★★★★★
(3117 ratings)
Provides a robust 5mg melatonin dose at a very low price per serving, offering excellent potency and value for those seeking a cost-effective sleep aid without time-release.
85 Value
Melatonin 3 mg
NOW
4.8
★★★★★
(4544 ratings)
Delivers an effective 3mg dose with a high number of servings (180) at a very low price per serving, offering great long-term value for consistent sleep support.
75 Value
Melatonin 3 mg
21st Century
4.8
★★★★★
(14990 ratings)
Another strong value option, providing a 3mg dose at a very low price per serving and a substantial quantity (200 servings), ideal for consistent, budget-friendly sleep aid.
98 Performance
Insomnitol
Designs for Health
4.6
★★★★★
(32 ratings)
A premium, multi-ingredient formula that likely targets various sleep mechanisms, offering a more comprehensive and potentially more effective solution for persistent sleep issues.
95 Performance
Ortho Sleep
AOR Advanced Orthomolecular Research Advanced
4.1
★★★★★
(129 ratings)
Another comprehensive sleep support product, designed to provide broader and deeper sleep benefits through a synergistic blend of ingredients beyond just melatonin.
92 Performance
Power to Sleep PM
Irwin Naturals
4.3
★★★★★
(2630 ratings)
This product is designed specifically as a 'Power to Sleep PM' blend, indicating it contains a combination of sleep-promoting ingredients for a more enhanced and holistic sleep experience.