True Calm
NOW
True Calm
4.6
★ ★ ★ ★ ★
(4164 ratings)
GABA 200 mg
Niacin 45 mg
Glycine 200 mg
Taurine 200 mg
Valerian 25 mg
Score 72.0
A comprehensive blend of amino acids, herbs, and B vitamins formulated to support general calm, mood, and sleep, though some key ingredient dosages are on the lower side.
Quantity: 90 Capsule(s)Servings size: 1 Veg Capsule(s) (90 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Brain Health
Heart Health
Fitness
leaderboard Score 72.0
A comprehensive blend of amino acids, herbs, and B vitamins formulated to support general calm, mood, and sleep, though some key ingredient dosages are on the lower side.
insights Analysis
The product leverages ingredients known for their calming effects on the nervous system. GABA is a primary inhibitory neurotransmitter, and its inclusion aims to reduce neural excitability. Glycine and Taurine also act as inhibitory neurotransmitters and play roles in brain function and stress response. Valerian root is a traditional herbal remedy for sleep and anxiety. The B vitamins (Niacinamide and B6) are crucial cofactors in neurotransmitter synthesis, while magnesium bisglycinate is a highly bioavailable form of magnesium known for its muscle relaxing and calming properties. While the blend is comprehensive, the dosages of Valerian (25mg) and Magnesium (6mg) are notably low compared to typical therapeutic dosages or the Recommended Daily Allowance (RDA) for Magnesium, which might limit their individual efficacy despite the synergistic blend. The Niacinamide form avoids the 'niacin flush' but also means it doesn't provide the same cholesterol-lowering benefits as nicotinic acid.
- Comprehensive formula targeting multiple aspects of mental well-being.
- Includes bioavailable Magnesium Bisglycinate.
- Niacinamide form avoids the uncomfortable 'niacin flush' experienced with other B3 forms.
- High review count suggests general satisfaction and reported effectiveness among users.
- Very low dosage of Valerian (25mg) for significant sedative or anxiolytic effects, typically found in much higher concentrations in targeted sleep aids.
- Extremely low dosage of Magnesium (6mg), which is insufficient to meet daily requirements or provide strong calming benefits from magnesium alone.
- The broad range of targeted goals might mean it offers less potent, targeted effects compared to single-ingredient or more focused high-dose supplements for specific issues.
- Individuals taking sedatives, tranquilizers, or other mood-altering medications should consult a healthcare professional before use due to potential additive effects with ingredients like GABA and Valerian.
- Pregnant or nursing women should consult a physician before use to ensure safety for both mother and child.
- Do not exceed the recommended dosage, as higher amounts could lead to unwanted side effects or interactions.
$11.39($0.12 per serving)
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bolt Effectiveness for goals
Research on the direct passage of orally supplemented GABA across the blood-brain barrier is mixed. Some studies suggest that while direct passage may be limited, it could still influence the gut-brain axis or peripheral nervous system. More research is ongoing to fully understand its central nervous system effects when taken orally.
Valerian root is traditionally used for its calming properties and to support restful sleep. Its effectiveness has been explored in various studies, with some indicating potential benefits for mild sleep disturbances and feelings of restlessness. Individual responses can vary.
Magnesium is an essential mineral involved in over 300 enzymatic reactions, including those crucial for nerve impulse transmission and muscle contraction. Magnesium bisglycinate is a chelated form, often chosen for its good absorption and tolerability. It contributes to electrolyte balance and normal psychological function.
Vitamin B6, specifically in its active form pyridoxal-5'-phosphate (P5P), is a coenzyme essential for the synthesis of several neurotransmitters. These include GABA, serotonin, and dopamine, which are involved in mood regulation and nervous system function. It is crucial for amino acid metabolism.
Niacinamide, a form of Vitamin B3, is a precursor to NAD and NADH, which are vital coenzymes in cellular energy production. It contributes to normal psychological function and the normal functioning of the nervous system. This role is essential for overall brain health and cellular metabolism.
schedule Dosage, timing & forms
Valerian root extract and GABA are often taken in the evening or before bedtime due to their association with relaxation. Some individuals may also use them during the day as needed, depending on their desired effect. It's generally advisable to follow the timing instructions provided on the supplement label.
Capsules are designed to dissolve in the digestive tract, releasing their contents for absorption. This form generally allows for a controlled release of amino acids like Taurine and Glycine, facilitating their uptake into the bloodstream. The specific absorption rate can vary based on individual physiology and other ingredients present.
Many B vitamins, including Niacin and B6, and amino acids like Taurine and Glycine, can typically be taken with or without food. However, taking them with food may help minimize potential mild stomach discomfort for some individuals. Always refer to the specific product's instructions for guidance.
Magnesium bisglycinate is a chelated form of magnesium known for its good bioavailability. It generally does not negatively interfere with the absorption of amino acids like GABA and Glycine. All these ingredients may be taken together, and their combined presence can support various physiological functions.
Niacinamide is a form of Vitamin B3 and generally supports cellular energy and nerve function. It is not typically known to significantly alter the timing or direct sedative effects of ingredients like Valerian or GABA. Its role is usually complementary, supporting overall neurological health.
health_and_safety Safety & interactions
Yes, valerian is known for its sedative properties, and when combined with other compounds that influence calming neurotransmitters like GABA, it may enhance feelings of drowsiness or relaxation. It is advisable to be aware of this potential effect, especially when operating machinery or driving.
Consuming alcohol with supplements containing ingredients like valerian root or GABA is generally not recommended. Both alcohol and these ingredients can have central nervous system depressant effects. This combination may lead to increased drowsiness, dizziness, and impaired coordination.
Valerian and GABA can potentially interact with central nervous system depressants, including prescription medications for anxiety or sleep aids. This interaction may heighten sedative effects, leading to increased drowsiness or slowed breathing. It is important to consult a healthcare professional before combining them.
While valerian is generally considered safe, rare reports of liver issues exist, especially with prolonged or high-dose intake. Niacinamide at typical supplement doses is less likely to cause liver problems than nicotinic acid. However, individuals with pre-existing liver conditions should consult a healthcare provider.
The safety of ingredients like valerian, GABA, and other amino acids during pregnancy and breastfeeding has not been sufficiently established through extensive human trials. Therefore, it is generally recommended that pregnant or nursing individuals avoid such supplements. Consulting a healthcare professional is advised.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Niacin | 45 mg |
Vitamin B6 | 8 mg |
Magnesium | 6.5 mg |
GABA | 200 mg |
Glycine | 200 mg |
Taurine | 200 mg |
Inositol | 100 mg |
Valerian | 25 mg |
Categories
Niacin 70.0
The product contains 45mg of Niacinamide, which is a good form for general B3 benefits without the common flushing reaction. This dose adequately supports nervous system function and energy metabolism as part of a blend.
Glycine 65.0
The product provides 200mg of Glycine, which is a supportive dose for its roles as an inhibitory neurotransmitter, potentially aiding in relaxation and improving sleep quality within a complex formula.
Taurine 65.0
Contains 200mg of Taurine, which is a reasonable dose for this beneficial amino acid within a multi-ingredient blend. Taurine supports nervous system function and has some cardiovascular benefits, contributing to the overall calming effect.
Goals
Stress Relief 75.0
This product contains a synergistic combination of GABA, Valerian, Glycine, Inositol, Magnesium, and Niacin/B6, all known to contribute to stress reduction and nervous system balance. However, the relatively low doses of Valerian and Magnesium might limit its full impact on significant or acute stress.
Mood Support 70.0
Ingredients like GABA, Inositol, Glycine, Niacin, and B6 are vital for healthy neurotransmitter function, which is critical for mood regulation. The blend offers general support, but for stronger mood regulation, individual doses of certain components might be considered low.
Sleep Support 70.0
Valerian, GABA, Glycine, and Magnesium are commonly utilized for their potential to improve sleep induction and overall sleep quality. While the combination is beneficial, the low Valerian and Magnesium dosages may only provide mild support for more pronounced sleep difficulties.
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