Mega D-3 5000 IU & MK-7 180 mcg
NOW
Mega D-3 5000 IU & MK-7 180 mcg
4.8
★ ★ ★ ★ ★
(25550 ratings)
Vitamin K 180 mcg
Score 90.0
An excellent D3/K2 (MK-7) combination at optimal dosages from a trusted brand, highly effective for bone and cardiovascular health with strong consumer reviews.
Quantity: 60 Capsule(s)Servings size: 1 Veg Capsule(s) (60 servings)
Selected goals:
Other goals:
Bone Health
Heart Health
Cardiovascular Support
General Health
leaderboard Score 90.0
An excellent D3/K2 (MK-7) combination at optimal dosages from a trusted brand, highly effective for bone and cardiovascular health with strong consumer reviews.
insights Analysis
The Mega D-3 5000 IU & MK-7 180 mcg from NOW is a highly effective supplement designed to leverage the synergistic relationship between Vitamin D3 and Vitamin K2 for bone and cardiovascular health. The inclusion of 180 mcg of Menaquinone-7 (MK-7) is crucial, as this is the highly bioavailable and long-lasting form of K2, essential for directing calcium absorbed by D3 to the bones and preventing its deposition in arteries. Nutritionists and online reviews frequently highlight the importance of this D3/K2 combination, praising its comprehensive approach to calcium metabolism and arterial flexibility. The widespread positive feedback across over 23,000 reviews attests to its efficacy and consumer trust in the NOW brand, which is known for its quality and affordability in the supplement market.
- Optimal dosages of D3 (5000 IU) and K2 (180 mcg MK-7) for synergistic benefits.
- Contains MK-7, the highly bioavailable and long-lasting form of Vitamin K2.
- Excellent synergy between D3 and K2 for bone mineralization and arterial health.
- Highly reputable brand (NOW) with extensive positive reviews validating product efficacy and trust.
- Good value for a high-quality combined D3/K2 supplement.
- The specific source of D3 (e.g., vegan lichen) is not detailed, which might be a consideration for some consumers.
- While 180mcg MK-7 is strong, some individuals might seek even higher K2 dosages for specific therapeutic interventions.
$10.40($0.17 per serving)
 Daily Vita | $ 10.40 | |
 iHerb | $ 14.75 | |
 Walmart | $ 14.75 | |
 Vitacost | $ 15.59 | |
| Daily Vita | $ 15.60 | |
 Pure Formulas | $ 16.42 |
bolt Effectiveness for goals
Vitamin K is essential for proper blood clotting and plays a significant role in bone metabolism. It helps the body produce proteins necessary for these vital bodily functions.
Vitamin K activates proteins such as osteocalcin, which are crucial for incorporating calcium into the bone matrix. This mechanism supports bone mineralization and helps maintain bone density.
Vitamin K1 (phylloquinone) is primarily effective for blood coagulation and is abundant in green leafy vegetables. Vitamin K2 (menaquinones) is more involved in bone and cardiovascular health, found in fermented foods and animal products, and has different bioavailabilities.
Emerging research suggests that Vitamin K, particularly K2, may help prevent arterial calcification by activating matrix Gla protein. This protein helps inhibit calcium deposition in soft tissues, supporting arterial flexibility.
Vitamin K works synergistically with calcium by helping to direct calcium to the bones and away from soft tissues like arteries. It activates proteins like osteocalcin for bone binding and matrix Gla protein to inhibit soft tissue calcification.
schedule Dosage, timing & forms
Recommended dosages for Vitamin K vary by age and form (K1 vs K2). For adults, the Adequate Intake (AI) for Vitamin K is 120 mcg per day for men and 90 mcg per day for women. Specific supplemental dosages may differ depending on individual needs and health goals.
Yes, dosages can differ between Vitamin K1 and K2 due to their varying potencies and half-lives. While K1 is measured in micrograms (mcg) for general intake, K2 (especially MK-7) may be effective at lower microgram doses due to its longer half-life. It's important to check the specific form and dosage on the supplement label.
Yes, Vitamin K is a fat-soluble vitamin, meaning it is best absorbed when taken with a meal containing some dietary fat. This helps facilitate its absorption into the body.
The two main forms of Vitamin K found in supplements are Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone). Vitamin K2 further has various subtypes, with MK-4 and MK-7 being the most common in supplements. Each form may have distinct roles and bioavailability.
There is no established Upper Limit (UL) for Vitamin K from food or supplements, as toxicity is rare. However, high doses of synthetic Vitamin K (menadione, K3) can be toxic, though this form is not typically found in supplements. Always adhere to recommended dosages and consult a healthcare provider if you have concerns.
health_and_safety Safety & interactions
Vitamin K plays a crucial role in blood clotting, which is the opposite effect of anticoagulant medications such as warfarin. Consuming inconsistent amounts of Vitamin K can alter warfarin's effectiveness, potentially making the blood thinner less effective or increasing bleeding risk. Individuals taking warfarin should maintain a consistent intake of Vitamin K and consult their healthcare provider.
Individuals taking anticoagulant medications like warfarin should consult their doctor before taking Vitamin K supplements due to potential interactions. People with certain liver conditions or those with a G6PD deficiency should also seek medical advice before supplementation. Always discuss new supplements with a healthcare provider.
Vitamin K supplements are generally considered safe for most healthy individuals when taken at recommended dosages. Side effects are uncommon but can include upset stomach, diarrhea, or allergic reactions in sensitive individuals. High doses of synthetic Vitamin K (menadione, K3) can be toxic, but this form is rarely used in supplements.
Vitamin K is essential during pregnancy and breastfeeding, and adequate intake is important for both mother and child. However, supplementation during these periods should only be undertaken under the guidance of a healthcare professional. High doses are generally not recommended without specific medical advice.
There is currently no established Tolerable Upper Intake Level (UL) for Vitamin K from food or supplements due to its low potential for toxicity. However, excessive intake, especially of synthetic forms, could potentially have adverse effects. It is always best to adhere to recommended dosages on supplement labels or as advised by a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin D-3 | 125 mcg |
Vitamin K-2 | 180 mcg |
Categories
Vitamin K 95.0
The product features 180mcg of Menaquinone-7 (MK-7), which is considered the superior form of Vitamin K2 due to its longer half-life and excellent bioavailability compared to MK-4. This dosage is effective for most individuals seeking the benefits of K2 for calcium metabolism and arterial health.
Goals
Bone Health 95.0
The combination of Vitamin D3, essential for calcium absorption, and Vitamin K2 (MK-7), crucial for directing calcium to bones and preventing its deposition in arteries, makes this product highly effective for bone mineralization and strength, aligning with nutritionist recommendations.
Heart Health 90.0
Vitamin K2, particularly MK-7, is well-regarded for its role in preventing arterial calcification by activating proteins that help clear calcium from soft tissues, directly contributing to arterial flexibility and overall heart health, a key benefit supported by research.
Similar to heart health, MK-7 aids in preventing arterial stiffening by ensuring calcium is properly utilized in bones rather than accumulating in arteries. This mechanism is central to maintaining healthy cardiovascular function, a benefit recognized in clinical studies and by health professionals.
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