BioCoenzymated Benfotiamine 150 mg plus Sulbutiamine
Natural Factors
BioCoenzymated Benfotiamine 150 mg plus Sulbutiamine
Thiamin 110 mg
Score 95.0
A premium, synergistic blend of Benfotiamine and Sulbutiamine for superior brain health, cognitive function, and sustained energy, leveraging enhanced bioavailability.
Quantity: 30 Capsule(s) • (30 servings)
Goals:
Score 95.0
A premium, synergistic blend of Benfotiamine and Sulbutiamine for superior brain health, cognitive function, and sustained energy, leveraging enhanced bioavailability.
Analysis
This product combines Benfotiamine (150mg), known for its superior absorption and ability to support metabolic pathways, with Sulbutiamine (110mg), a synthetic thiamine derivative that readily crosses the blood-brain barrier. Sulbutiamine is particularly noted for its nootropic properties, including enhancing memory, reducing fatigue, and improving mood. This dual-action formula targets both general B1 metabolism and specific neurological enhancement, making it a premium choice for comprehensive brain and energy support, as frequently highlighted by online nutrition experts and user reviews.
Pros
- Unique combination of two highly bioavailable and brain-penetrating Thiamin forms.
- Sulbutiamine offers specific nootropic and anti-fatigue benefits.
- Excellent for targeted brain health and cognitive support.
- Positive user reviews regarding its efficacy for energy and focus.
Cons
- Significantly more expensive per serving compared to other Thiamin supplements.
- Specific combination might be overkill for general B1 deficiency.
- Lower dosage of Benfotiamine compared to some standalone products (150mg vs 300mg).
$13.97($0.46 per serving)
 iHerb | $ 13.97 |
Effectiveness for goals
Thiamin, also known as Vitamin B1, is crucial for converting carbohydrates into energy and plays a vital role in metabolism. It supports the healthy function of the nervous system, muscles, and heart. Maintaining adequate thiamin levels is essential for overall cellular function.
Yes, thiamin supplements are highly effective in treating and preventing thiamin deficiency. Deficiency can result from inadequate dietary intake, excessive alcohol consumption, or certain medical conditions. Supplementation helps to restore normal thiamin levels and alleviate associated symptoms.
High-dose thiamin administration is a critical and effective treatment for Wernicke-Korsakoff syndrome (WKS), a severe neurological disorder often associated with chronic alcohol abuse and thiamin deficiency. Early and aggressive supplementation can prevent the progression of Wernicke's encephalopathy and may improve outcomes for Korsakoff's psychosis. It is often administered intravenously in clinical settings.
Thiamin supplementation is the primary and highly effective treatment for beriberi, a disease caused by severe thiamin deficiency. It can reverse the various symptoms affecting the cardiovascular system (wet beriberi) and the nervous system (dry beriberi). Prompt treatment is crucial for recovery.
Some research suggests that certain forms of thiamin, such as benfotiamine, may be effective in managing symptoms of diabetic neuropathy. It is thought to work by influencing metabolic pathways and reducing oxidative stress, which contribute to nerve damage in individuals with diabetes. However, more large-scale clinical trials are needed to confirm these findings.
Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for thiamin is 1.2 mg per day for adult men and 1.1 mg per day for adult women. These amounts are generally sufficient to prevent deficiency in healthy individuals. Higher dosages may be used under professional guidance for specific conditions.
Yes, Thiamin supplements can generally be taken with or without food. Taking it with food may help some individuals avoid mild stomach upset. Consistent intake, rather than meal timing, is often more critical for absorption.
No Upper Tolerable Intake Level (UL) has been established for Thiamin due to a lack of evidence of adverse effects from high intakes. Even at very high doses, Thiamin is generally considered safe because it is water-soluble and any excess is typically excreted in urine. However, extremely high doses should only be used under professional supervision.
There is no specific "best" time of day to take Thiamin, as its absorption is not significantly affected by morning or evening intake. Some individuals prefer to take B vitamins in the morning to align with the body's natural energy cycles. Consistency in taking the supplement at the same time each day is often more beneficial.
Yes, Thiamin supplements are commonly available as thiamin hydrochloride and thiamin mononitrate, which are synthetic forms readily absorbed. Benfotiamine and sulbutiamine are also available, which are lipid-soluble derivatives sometimes used for specific purposes due to their enhanced bioavailability. The choice of form may depend on individual needs and professional recommendations.
Safety & interactions
Chronic alcohol consumption can significantly impair Thiamin absorption and utilization, leading to a deficiency. Alcohol also increases the body's Thiamin requirements and its excretion. This interaction is a major cause of Thiamin deficiency in individuals with alcohol use disorder.
Conditions such as chronic alcoholism, bariatric surgery, certain malabsorption syndromes, and persistent vomiting can lead to Thiamin deficiency. While Thiamin supplementation is often critical in these cases, individuals with specific liver or kidney conditions should discuss supplement use with their healthcare provider. This ensures appropriate dosage and monitoring for any potential interactions.
Thiamin, or Vitamin B1, is generally considered safe when taken at recommended doses. High doses typically do not cause serious side effects because it is a water-soluble vitamin, and excess is usually excreted by the body. Allergic reactions are rare but can occur, especially with intravenous administration.
Thiamin is a water-soluble vitamin, meaning the body excretes excess amounts in urine. Consequently, there is no established Upper Limit (UL) for Thiamin, as no toxicity has been reported from oral intake. However, extremely high doses administered intravenously have rarely been associated with adverse effects.
Thiamin is essential for fetal development and is considered safe for pregnant and breastfeeding individuals at recommended daily allowances. Higher doses might be prescribed by a healthcare provider for specific deficiencies. It is always advisable to discuss any new supplement use with a doctor during these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Thiamin | 110 mg |
Benfotiamine | 150 mg |
Sulbutiamine | 13.5 mg |
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overviewCategories
Thiamin 95.0
This product represents a cutting-edge approach within the Thiamin category by combining two highly advanced, lipid-soluble forms. This dual approach maximizes bioavailability and targets both general metabolic needs and specific neurological demands, setting it apart from standard Thiamin supplements.
Goals
Brain Health 98.0
This product excels in brain health due to the dual action of Benfotiamine and Sulbutiamine, both highly permeable to the blood-brain barrier. Sulbutiamine, in particular, is valued by nootropic communities for its direct impact on brain neurotransmitter systems, offering superior brain support.
Cognitive Support 98.0
The inclusion of Sulbutiamine makes this product exceptionally strong for cognitive support, as it is researched for improving memory, attention, and executive function. Benfotiamine further enhances overall brain metabolic efficiency crucial for optimal cognition.
Energy 95.0
Both Benfotiamine and Sulbutiamine contribute to efficient energy metabolism, with Sulbutiamine specifically known for its ability to reduce fatigue and enhance physical performance, offering a noticeable energy boost beyond standard Thiamin.
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With 250mg of Benfotiamine per serving at a significantly lower price, this product provides outstanding value for those looking for the superior benefits of Benfotiamine without the premium cost of the Sulbutiamine combination.
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Doctor's Best provides a full 300mg of Benfotiamine at a competitive price, making it a solid value choice for individuals seeking the enhanced bioavailability benefits of this Thiamin derivative.
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While not solely a B1 product, it contains a high 600mg dose of Benfotiamine, which could be considered 'better' for those seeking a higher Benfotiamine concentration, even if it has other ingredients not directly related to Thiamin.
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For comprehensive B vitamin support that covers more than just Thiamin, Solgar's B-Complex offers a full spectrum of high-potency B vitamins, synergistically enhancing overall energy, metabolism, and nervous system health.
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This provides a very high 500mg dose of standard Thiamin, which, while not as bioavailable as the product being analyzed, offers a potent Thiamin load for those needing significant B1 supplementation.