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Beyond CoQ10

Natures Plus
4.7
★ ★ ★ ★ ★
(400 ratings)
Coenzyme Q-10 200 mg
Selenium 70 mcg
Product Image
Score72
High-potency ubiquinol in a suitable softgel, undermined by an opaque carrier blend and low-value mineral extras.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Heart Health
Energy
Anti-Aging
Metabolism Boost
Anti-Inflammatory Support
Cardiovascular Support
General Health
Immunity

Score 72

High-potency ubiquinol in a suitable softgel, undermined by an opaque carrier blend and low-value mineral extras.
How scoring works

Also available as

1 option
30 servings Selenium 70 mcg, Coenzyme Q-10 200 mg • 30 Softgel(s) • 30 servings $41.61 ($1.38 per serving)
$75.61($1.26 per serving)
iHerb
$ 75.61
Amazon
$ 75.61
Vitacost
$ 83.19
Report prices

Analysis

Ubiquinol is the reduced CoQ10 form and is supplied at a substantial amount for cardiac and cellular-energy support. The softgel contains fat, which is well aligned with absorption of this fat-soluble compound.

Selenomethionine adds a useful antioxidant cofactor, while calcium, magnesium, and potassium are token additions. The 440 mg branded blend does not disclose its individual components, making the formula beyond ubiquinol difficult to evaluate.

The product suits adults seeking high-potency ubiquinol more than users wanting broad heart or general-health coverage. Its strongest use is targeted mitochondrial support, not direct lipid management, vascular tone, or thermogenesis.

Who is it for
  • Adults seeking 200 mg ubiquinol
  • Users focused on cardiac energy
  • People who prefer a fat-containing softgel
Best for
  • High-potency CoQ10 supplementation
  • Cardiac energy support
  • Mitochondrial antioxidant support

Pros

  • Uses preferred-form ubiquinol
  • Substantial 200 mg amount
  • Softgel fat supports delivery
  • Includes selenomethionine

Cons

  • Large proprietary carrier blend
  • Tiny mineral amounts add little
  • Does not address lipid management
  • Limited broad-nutrition coverage

Warnings

  • Ubiquinol may reduce warfarin's anticoagulant effect, so people using warfarin need prescriber guidance and clotting monitoring when starting or stopping it.

Nutrient quality

90 Highest impact

Ubiquinol and a fat-containing softgel support absorption at a substantial amount. Several tiny mineral additions and the unclear UbiquiMax entry add less certain value.

.

Ingredient transparency

66 High impact

The main active amounts are mostly visible, making the core formula possible to assess. Serving directions and non-active ingredients are missing, and any named blend further limits clarity.

.

Customer satisfaction

67 High impact

The supplied average is very strong and the response volume is moderate. No detailed feedback is provided to assess recurring complaints or fit with the intended purpose.

.

Value for money

63 Moderate impact

Premium form, substantial dosing, and supportive delivery justify part of the higher cost. The serving remains expensive and some added components have limited practical value.

.
Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB CoverageB+ Formula Quality
Magnesium · 4 mgCoenzyme Q-10 · 200 mg

Ubiquinol provides a preferred CoQ10 form at a substantial amount for cardiac energy and antioxidant support. A fat-containing softgel should aid absorption.

Selenium adds antioxidant breadth, while the remaining minerals are too small to contribute meaningfully. The proprietary UbiquiMax blend hides some components, but the central ubiquinol amount remains fully clear.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Selenium Mixed 89 studies
Energy
Energy
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageB+ Formula Quality
Magnesium · 4 mgPotassium · 9 mgCoenzyme Q-10 · 200 mg

The high ubiquinol amount directly supports mitochondrial ATP production in a fat-containing softgel. Selenium adds antioxidant support, while the small mineral additions make little practical difference.

The proprietary cofactor blend does not disclose individual components or doses, limiting assessment of the formula beyond ubiquinol. CoQ10 may reduce warfarin's anticoagulant effect, so people whose warfarin dose is being managed need prescriber guidance.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA+ Strength of SupportC CoverageB Formula Quality
Coenzyme Q-10 · 200 mgMagnesium · 4 mg

CoQ10 directly supports mitochondrial energy production and antioxidant protection, two mechanisms relevant to age-related cellular decline. The 200 mg amount is clearly disclosed as preferred-form ubiquinol.

Softgel fat and the reduced form support absorption. A proprietary cofactor blend adds uncertainty around an otherwise strong core.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC+ CoverageB+ Formula Quality
Magnesium · 4 mgCoenzyme Q-10 · 200 mg

Ubiquinol provides a substantial active-form CoQ10 dose for mitochondrial energy production. Softgel fat and selected cofactors support delivery and cellular use.

Selenium adds a thyroid-related pathway, but the other minerals are present only in tiny amounts and part of the formula remains proprietary. The product offers strong mitochondrial depth without direct thermogenic or glycemic-control support.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Selenium Mixed 28 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A- Goal FitA Strength of SupportC+ CoverageC+ Formula Quality
Coenzyme Q-10 · 200 mg

High-dose ubiquinol provides well-absorbed mitochondrial antioxidant support, while selenium supports antioxidant enzyme activity. The 200 mg ubiquinol amount is substantial and the fat-containing softgel suits delivery.

A 440 mg proprietary UbiquiMax blend hides its contents, making additional pathway claims impossible to verify. Ubiquinol may reduce warfarin response, so people using warfarin need clotting monitoring when starting or stopping it.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Selenium Supportive 34 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitA Strength of SupportD+ CoverageB- Formula Quality
Potassium · 9 mgMagnesium · 4 mgCoenzyme Q-10 · 200 mgSelenium · 70 mcg

CoQ10 supports cardiac energy production and antioxidant defense and may be useful when tissue levels are low. It does not directly cover lipid management, vascular calcium balance, or omega-3 pathways.

The ubiquinol amount is substantial, and the active reduced form in a softgel supports absorption. A proprietary companion blend obscures several added ingredients and their roles.

Study evidence
Coenzyme Q-10 Supportive 89 studies

Ingredients

IngredientAmount per serving
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Calcium (Calcium Citrate)
 10 mg
Magnesium (Magnesium Citrate)
 4 mg
Selenium (Selenomethionine)
 70 mcg
Potassium (Potassium Citrate)
 9 mg
Ubiquinol (activated Coenzyme Q10)
 200 mg
UbiquiMax
440 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 (activated Coenzyme Q10) · 200 mg OverallScore92
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

Ubiquinol provides the preferred active form at a substantial dose. The fat-containing softgel supports absorption of this fat-soluble compound. Its premium price is partly justified by form, delivery, and included cofactors.

View ingredientView products
Selenium (Selenomethionine) · 70 mcg OverallScore68
A- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Selenomethionine provides a highly bioavailable organic source, but the label does not identify the active isomer. The modest amount may contribute to intake but falls below the preferred maintenance range. Standardized selenium cost is poor when judged for this mineral alone.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
A focused softgel supplies the same substantial ubiquinol amount without the original opaque UbiquiMax blend. Selenium is omitted, but the core CoQ10 dose is easier to assess.
81 Performance

Ubiquinol Active CoQ10 200 mg

Natural Factors
The same 200 mg reduced CoQ10 amount is paired with flaxseed oil for a clear fat-based delivery system. It omits selenium and still carries a relatively high serving cost, but disclosure is simpler.
87 Performance

QH-absorb 100 mg

Jarrow Formulas
A clearly disclosed ubiquinol softgel offers a lower maintenance amount with favorable serving economics. The dose is lower than the original, but the focused formula avoids the unclear 440 mg branded blend and may be easier to tailor.
87 Budget

Se-Methyl L-Selenocysteine 200 mcg

Life Extension
The focused organic selenium formula costs much less per serving while providing more selenium. It does not contain CoQ10, so it cannot replace the original 200 mg ubiquinol for CoQ10-focused use.
87 Budget

Selenium 200 mcg

Nature's Way
L-selenomethionine provides a precise organic selenium serving at a small fraction of the recurring cost. CoQ10 is absent, making it suitable only when selenium rather than ubiquinol is the main need.
87 Budget

Selenium 200 mcg

Source Naturals
A well-absorbed selenium form and long supply make this a much cheaper focused option. It omits the original ubiquinol, so the lower cost comes with substantially narrower coverage.
87 Value

CoQ10 200 mg

California Gold Nutrition
The full 200 mg CoQ10 amount is retained in conventional ubiquinone form at much lower recurring cost. Conversion to ubiquinol is required, and selenium is absent, but active value is substantially stronger.
84 Value

High Absorption CoQ10 200 mg

Doctor's Best
A 200 mg ubiquinone serving with piperine provides a comparable nominal dose at far lower cost. Piperine may alter medicine exposure, and the formula does not preserve selenium.
84 Value

CoQ10 200 mg

Nature Made
A straightforward 200 mg ubidecarenone softgel offers comparable CoQ10 quantity with much better serving economics. The conventional form requires conversion to ubiquinol and does not include selenium.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost Heart Health forCoenzyme Q-10
  2. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
    Ho MJ; Li EC; Wright JM · The Cochrane database of systematic reviews · 2016
    Meta-analysis50 participants3 studies pooledHeart Health forCoenzyme Q-10
  3. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  4. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  5. The Effects of Coenzyme Q10 Supplementation on Blood Pressures Among Patients with Metabolic Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    Tabrizi R; Akbari M; Sharifi N; Lankarani KB; Moosazadeh M; Kolahdooz F; Taghizadeh M; Asemi Z · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018
    Meta-analysis684 participants17 studies pooledHeart Health forCoenzyme Q-10
  6. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis.
    Sahebkar A; Simental-Mendía LE; Stefanutti C; Pirro M · Pharmacological research · 2016
    Meta-analysis409 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  7. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  8. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledHeart Health Cardiovascular Support forCoenzyme Q-10
  9. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsMetabolism Boost Anti-Aging forCoenzyme Q-10
  10. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  11. Coenzyme Q10: an independent predictor of mortality in chronic heart failure.
    Molyneux SL; Florkowski CM; George PM; Pilbrow AP; Frampton CM; Lever M; Richards AM · Journal of the American College of Cardiology · 2008
    Cohort study236 participantsHeart Health forCoenzyme Q-10
  12. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  13. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  14. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  15. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  16. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  17. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  18. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  19. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  20. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  21. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  22. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  23. Selenium and the course of mild Graves' orbitopathy.
    Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
    Randomized trial159 participantsAnti-Inflammatory Support forSelenium
  24. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsAnti-Inflammatory Support Metabolism Boost forSelenium
  25. Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
    Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
    Randomized trial60 participantsAnti-Inflammatory Support forSelenium
  26. The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
    Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
    Meta-analysis656 participants11 studies pooledAnti-Inflammatory Support forSelenium
  27. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
    Randomized trial33 participantsAnti-Inflammatory Support forSelenium
  28. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  29. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  30. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  31. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  32. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  33. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  34. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  35. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  36. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  37. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  38. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  39. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  40. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  41. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  42. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  43. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  44. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  45. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  46. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  47. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  48. Selenium concentration is associated with occurrence and diagnosis of three cardiovascular diseases: A systematic review and meta-analysis.
    Yang L; Qi M; Du X; Xia Z; Fu G; Chen X; Liu Q; Sun N; Shi C; Zhang R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Meta-analysis49 studies pooledHeart Health forSelenium
  49. Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.
    Rayman MP; Stranges S; Griffin BA; Pastor-Barriuso R; Guallar E · Annals of internal medicine · 2011
    Randomized trial501 participantsHeart Health forSelenium
  50. Exploring the Impact of Selenium Supplementation on Nutritional, Inflammatory, and Cardiac Function in Chronic Heart Failure Patients: A Novel Approach to Managing Deficiency.
    Kou L; Meng F; Fu G; Zhang R · Cardiovascular toxicology · 2025
    Meta-analysis191 participantsHeart Health forSelenium
  51. Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.
    Zhu D; Zhong Q; Lin T; Song T · Frontiers in nutrition · 2023
    Cohort study3,063 participantsHeart Health forSelenium
  52. Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018.
    Shi W; Su L; Wang J; Wang F; Liu X; Dou J · Annals of medicine · 2022
    Cross-sectional study39,438 participantsHeart Health forSelenium
  53. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  54. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  55. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  56. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  57. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  58. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  59. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
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