PQQ Energy
NOW
PQQ Energy
4.6
★ ★ ★ ★ ★
(1785 ratings)
Vitamin B12 1000 mcg
Coenzyme Q-10 30 mg
Acetyl L-Carnitine 200 mg
Score 75.0
A combination of bioavailable Vitamin B12 and Acetyl-L-Carnitine aiming for energy and cognitive support. Excellent B12 form and dose, but the ALCAR quantity is on the lower side for strong effects, making it a moderate value proposition.
Quantity: 30 Capsule(s)Servings size: 1 Veg Capsule(s) (30 servings)
Selected goals:
Other goals:
Brain Health
Energy
Anti-Aging
Mood Support
Cognitive Support
leaderboard Score 75.0
A combination of bioavailable Vitamin B12 and Acetyl-L-Carnitine aiming for energy and cognitive support. Excellent B12 form and dose, but the ALCAR quantity is on the lower side for strong effects, making it a moderate value proposition.
insights Analysis
NOW's PQQ Energy is formulated with Methylcobalamin (1000mcg) and Acetyl-L-Carnitine HCl (200mg) to support energy, brain health, mood, cognitive function, and metabolism. The choice of Methylcobalamin for B12 is commendable, as it's the active coenzyme form, readily utilized by the body, which aligns with modern nutritional recommendations over cheaper Cyanocobalamin forms. Online reviews generally reflect positive experiences with energy and mood, likely due to the B12 component. However, nutritionists and research often suggest higher dosages of Acetyl-L-Carnitine for a more pronounced impact on brain health, memory, and metabolic support. A 200mg dose might provide subtle benefits but falls short of the quantities typically associated with significant clinical outcomes. Therefore, while a decent foundational product, it may not deliver the full potential across all its ambitious goals due to the moderate ALCAR dosage, especially when considering its price point.
- Utilizes Methylcobalamin, the highly bioavailable and active form of Vitamin B12.
- Combines two well-regarded ingredients known for their roles in energy production and neurological function.
- Produced by NOW, a reputable brand recognized for quality and transparency.
- The Acetyl-L-Carnitine dosage (200mg) is relatively low compared to research-backed amounts for significant cognitive and metabolic benefits.
- The price per serving is on the higher side given the modest dosage of Acetyl-L-Carnitine, reducing its overall cost-effectiveness.
- May not provide pronounced effects across all stated goals due to conservative ingredient dosing.
$15.91($0.53 per serving)
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bolt Effectiveness for goals
Vitamin B12 is essential for DNA synthesis, red blood cell formation, and neurological function. It plays a key role in the metabolism of every cell in the human body. Adequate B12 levels are crucial for overall health.
Vitamin B12 is essential for red blood cell formation, DNA synthesis, and neurological function. Supplementation can help prevent B12 deficiency, which may lead to fatigue, weakness, and nerve damage. It plays a crucial role in maintaining overall energy levels and cognitive health.
Individuals with dietary restrictions (e.g., vegans, strict vegetarians), older adults, people with malabsorption issues, or those taking certain medications are at higher risk of B12 deficiency. For these groups, supplementation can be highly effective in preventing or correcting deficiency-related symptoms. It's also beneficial for those with confirmed B12 deficiency.
Vitamin B12 plays a critical role in the body's energy production processes by assisting in the metabolism of fats and carbohydrates. While it won't provide a direct energy boost like stimulants, correcting a B12 deficiency can significantly alleviate fatigue and improve perceived energy levels. Its impact on red blood cell formation also contributes to oxygen transport, which is vital for energy.
For individuals with a Vitamin B12 deficiency, supplementation can significantly improve fatigue and energy levels. In those without a deficiency, evidence for a direct energy boost from B12 supplementation is less clear. It primarily supports energy metabolism by enabling cells to function correctly.
schedule Dosage, timing & forms
For general maintenance, dosages often range from 2.4 mcg to 1000 mcg daily, depending on individual needs and health status. Higher doses are typically used to correct deficiencies or for certain medical conditions. It's advisable to consult a healthcare professional for personalized dosage recommendations.
Typical dosages for Acetyl L-Carnitine (ALCAR) range from 630 mg to 2,500 mg per day, often divided into multiple doses. The specific dosage can depend on the desired effect, such as cognitive support or exercise performance. It's best to start with a lower dose and adjust as needed, under professional guidance.
Vitamin B12 is most commonly available as cyanocobalamin, which the body converts into active forms like methylcobalamin and adenosylcobalamin. Methylcobalamin is also a popular active form offered directly in supplements. Other forms include hydroxocobalamin, often used in injections.
Vitamin B12 is commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms. Supplements come as capsules, sublingual tablets, liquids, and nasal sprays.
Acetyl L-Carnitine can be taken at any time of day, with or without food, though some prefer to take it in the morning or before exercise. Dividing the dose throughout the day may help maintain stable levels. If stomach upset occurs, taking it with a meal might be beneficial.
health_and_safety Safety & interactions
Yes, Vitamin B12 can interact with certain prescription medications. For example, some drugs for stomach acid reduction, like proton pump inhibitors and H2 receptor antagonists, can decrease B12 absorption. Metformin, a diabetes medication, may also lower B12 levels.
Vitamin B12 is generally considered safe, and side effects are uncommon due to its water-soluble nature. In rare cases, some individuals might experience mild gastrointestinal upset or skin reactions. Extremely high doses administered via injection have been linked to potential acne in some individuals.
Yes, Acetyl L-Carnitine can potentially interact with certain medications. This includes blood thinners (anticoagulants), thyroid hormones, and some medications used to treat seizures. Consulting a healthcare provider before use is recommended if you are on medication.
Vitamin B12 supplementation is generally well-tolerated. For most individuals, taking recommended doses does not result in significant side effects. Some people might experience mild reactions like itching or diarrhea, though these are uncommon.
Acetyl L-Carnitine is generally well-tolerated. Possible side effects, though typically mild, can include nausea, vomiting, stomach upset, heartburn, diarrhea, and a "fishy" body odor. These are usually associated with higher doses.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B12 | 1000 mcg |
PQQ | 20 mg |
Acetyl-L-Carnitine | 200 mg |
Coenzyme Q10 | 30 mg |
Categories
Vitamin B12 90.0
The product provides 1000mcg of Methylcobalamin, which is an excellent dosage and the most bioavailable form of Vitamin B12. This makes it highly effective for individuals needing B12 supplementation, contributing significantly to energy and nerve health.
Acetyl L-Carnitine 60.0
It contains 200mg of Acetyl-L-Carnitine HCl. While a beneficial compound for mitochondrial function and brain health, this dosage is considerably lower than the 500mg-2000mg range typically used in studies for significant effects on cognitive function, energy, or fat metabolism, thereby limiting its full potential in this category.
Goals
Energy 80.0
Vitamin B12 is essential for cellular energy production and red blood cell formation, directly combating fatigue. Acetyl-L-Carnitine also contributes to energy by facilitating fatty acid transport into mitochondria. The combination offers a solid basis for energy support, though the ALCAR dose might offer more subtle effects.
Brain Health 75.0
Both Methylcobalamin B12 and Acetyl-L-Carnitine play vital roles in neurological function. B12 is crucial for nerve health, while ALCAR supports neurotransmitter production important for cognitive processes. However, the 200mg ALCAR dosage is below levels often associated with substantial cognitive enhancement in studies.
Cognitive Support 75.0
This goal is well-addressed by Vitamin B12's role in nerve health and Acetyl-L-Carnitine's ability to cross the blood-brain barrier and contribute to acetylcholine synthesis, a key neurotransmitter for memory. However, for a more pronounced cognitive boost, the ALCAR dosage could be higher based on common research findings.
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