Mega GLA Sesame Lignans
Life Extension
Mega GLA Sesame Lignans
4.6
★ ★ ★ ★ ★
(735 ratings)
Gamma Linolenic Acid 400 mg
Score 80.0
A high-quality GLA supplement from borage oil, enhanced with sesame lignans for synergistic benefits. It's well-regarded for supporting skin, joint, and mood health, though it comes at a premium price.
Quantity: 30 Softgel(s)Servings size: 1 Softgel(s) (30 servings)
Selected goals:
Other goals:
Skin Health
Joint Health
Mood Support
leaderboard Score 80.0
A high-quality GLA supplement from borage oil, enhanced with sesame lignans for synergistic benefits. It's well-regarded for supporting skin, joint, and mood health, though it comes at a premium price.
insights Analysis
Mega GLA Sesame Lignans by Life Extension is a specialized supplement primarily delivering Gamma-Linolenic Acid (GLA) at a substantial dose of 400mg per softgel, sourced from borage seed oil. Borage oil is recognized by nutritionists as one of the richest natural sources of GLA, an omega-6 fatty acid known for its anti-inflammatory properties. The inclusion of 10mg of sesame lignan extract is a distinguishing feature, as lignans are studied for their potential to enhance the metabolic effects of fatty acids and provide antioxidant benefits, potentially boosting the efficacy of GLA. Online reviews generally reflect high satisfaction, with users often reporting noticeable improvements related to skin and joint discomfort. The brand 'Life Extension' is well-regarded in the supplement industry for its rigorous quality control and research-driven product development.
- High concentration of Gamma-Linolenic Acid (GLA) per serving (400mg).
- Includes sesame lignans, which may enhance GLA's effectiveness and offer additional antioxidant benefits.
- Sourced from borage oil, a superior natural source of GLA.
- Manufactured by Life Extension, a reputable brand known for quality and research-backed formulations.
- Higher price per serving compared to some other GLA or omega supplements.
- The direct impact on mood support is less robustly supported compared to skin and joint benefits, which are more widely studied for GLA.
- Individuals on blood-thinning medications should consult a healthcare professional before use due to the potential effects of fatty acids on blood clotting.
- May cause mild gastrointestinal upset in sensitive individuals, though uncommon.
$19.50($0.65 per serving)
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bolt Effectiveness for goals
Gamma Linolenic Acid (GLA) is an omega-6 fatty acid found in certain plant oils. It is a precursor to molecules that regulate inflammation and support cellular function. The body can produce GLA from linoleic acid, but direct supplementation is also common.
Some research suggests GLA supplements may help improve symptoms like itching and redness associated with eczema, particularly in certain individuals. However, results from studies have been mixed, and more consistent evidence is needed to confirm widespread effectiveness.
GLA is an omega-6 fatty acid that the body can convert into substances with anti-inflammatory properties. It is often studied for its potential role in supporting skin health and managing certain inflammatory conditions.
GLA is a component of skin ceramides, which are crucial for maintaining the skin's barrier function and hydration. Supplementation may help improve skin moisture, elasticity, and overall skin health, particularly in cases of dry skin.
Some research suggests GLA may help improve symptoms of atopic dermatitis (eczema) by reducing inflammation and improving skin barrier function. However, study results have been mixed, with some showing modest benefits and others no significant effect. More robust clinical trials are needed for conclusive evidence.
schedule Dosage, timing & forms
Common daily dosages for GLA supplements often range from 200 mg to 500 mg, though specific recommendations can vary based on the product and intended use. The total amount of GLA is typically derived from oils like Evening Primrose Oil or Borage Oil, which contain different concentrations. Always refer to product labels for precise dosage instructions.
The most common dietary sources of GLA are plant oils, particularly evening primrose oil, borage oil, and black currant seed oil. These oils are frequently used in supplement form due to their concentrated GLA content. Smaller amounts can also be found in certain seeds.
GLA is primarily available in softgel capsule form, usually containing oils such as Evening Primrose Oil (EPO), Borage Oil, or Black Currant Seed Oil. These oils are rich in GLA and are the most common way to supplement this fatty acid. While some specialty products may offer liquid forms, capsules are predominant.
Typical daily dosages for GLA vary depending on the condition being addressed, often ranging from 200 mg to 500 mg of pure GLA. For specific conditions like eczema or rheumatoid arthritis, dosages can sometimes be higher, up to 1000 mg of GLA per day. It is important to check the GLA content, not just the oil content.
The main plant-based sources of GLA used in supplements are Evening Primrose Oil (EPO), Borage Oil (also known as Starflower Oil), and Black Currant Seed Oil. Each of these oils contains varying concentrations of GLA, with Borage Oil typically having the highest percentage. These oils are extracted and encapsulated for supplementation.
health_and_safety Safety & interactions
Yes, GLA may interact with certain medications. It has been reported to potentially interact with blood-thinning medications (anticoagulants/antiplatelets) due to its effects on platelet aggregation. Individuals on such medications should consult a healthcare professional.
GLA may have antiplatelet effects, which could potentially slow blood clotting. This interaction is particularly relevant for individuals taking anticoagulant or antiplatelet medications. It is advisable to exercise caution and consult a healthcare professional, especially before surgery.
Common side effects of GLA are generally mild and can include digestive issues such as soft stools, diarrhea, belching, and gas. Some individuals might also experience headache or nausea. These effects usually subside as the body adjusts or with dosage reduction.
Individuals with certain seizure disorders should use GLA with caution, as some early research suggested a potential, though unconfirmed, link to seizures. Those with bleeding disorders or who are scheduled for surgery should also be cautious due to potential effects on blood clotting. Always discuss with a doctor if you have pre-existing conditions.
Contraindications for GLA include known hypersensitivity to the supplement or its components. Individuals with certain types of seizure disorders have been advised to use caution. It should also be avoided by those scheduled for surgery due to its potential effects on blood clotting, unless approved by a doctor.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Calories | 5 Calorie(s) |
Total Fat | 0.5 Gram(s) |
Saturated Fat | 0 Gram(s) |
Gamma-Linolenic Acid | 400 mg |
Sesame seed Lignan extract | 10 mg |
Categories
Gamma Linolenic Acid 90.0
This product excels within the Gamma Linolenic Acid collection due to its high and effective dose of 400mg GLA per serving, sourced from high-quality borage oil. The additional sesame lignans further differentiate it, potentially enhancing GLA's metabolism and bioavailability, making it a premium choice for direct GLA supplementation.
Goals
Skin Health 90.0
GLA is widely recognized by dermatologists and nutritionists for its role in maintaining skin barrier function and reducing inflammatory skin conditions like eczema and dryness. The 400mg dose is therapeutic and many online reviews specifically highlight improvements in skin hydration and reduction in redness, making it highly effective for this goal.
Joint Health 85.0
The anti-inflammatory properties of GLA can significantly help alleviate joint pain and stiffness, especially in conditions like rheumatoid arthritis, by influencing prostaglandin synthesis. The potent 400mg dosage provides a solid foundation for supporting joint comfort, aligning with clinical studies suggesting GLA's benefit in inflammatory joint conditions.
Mood Support 60.0
While GLA contributes to overall cellular health and can indirectly influence nervous system function, its direct role in mood support is less pronounced and less consistently documented than its effects on skin and joints. Any mood benefits are likely secondary to its anti-inflammatory actions or its role in hormonal balance, rather than being a primary treatment for mood disorders.
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