St. John's Wort Extract Alcohol-Free
Nature's Answer
St. John's Wort Extract Alcohol-Free
4.5
★ ★ ★ ★ ★
(912 ratings)
St. John's Wort 1000 mg
Score 58.0
A costly alcohol-free liquid extract of St. John's Wort, offering convenience and potentially faster absorption, but lacking standardization for its active compounds, which limits its scientific appeal.
Quantity: 1 Fluid Ounce(s)Servings size: 1 mL (30 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 58.0
A costly alcohol-free liquid extract of St. John's Wort, offering convenience and potentially faster absorption, but lacking standardization for its active compounds, which limits its scientific appeal.
insights Analysis
This Nature's Answer product stands out as an alcohol-free liquid extract, appealing to those who prefer liquid forms or wish to avoid alcohol. Liquid extracts can offer faster absorption and flexible dosing. However, despite being an 'extract,' it does not specify standardization to hypericin, which is crucial for consistent potency in St. John's Wort supplements. At $0.42 per serving, it is the most expensive product among those analyzed, significantly impacting its value proposition. While it has a moderate review count, the high cost per serving for an unstandardized extract might be a deterrent for many.
- Alcohol-free liquid form for easy absorption and flexible dosing
- Very expensive per serving
- Lacks standardization of active compounds (e.g., hypericin)
- St. John's Wort can interact with numerous medications, including antidepressants, birth control, and blood thinners. Consult a healthcare professional before use, especially if on other medications.
- Photosensitivity may occur.
$12.74($0.42 per serving)
 Vitacost | $ 12.74 | |
 iHerb | $ 12.74 | |
 Pure Formulas | $ 12.75 | |
 Amazon | $ 14.99 |
bolt Effectiveness for goals
Some research suggests St. John's Wort may be effective for mild to moderate depression. Its use for severe depression is not well-supported by evidence. Consultation with a healthcare professional is advisable before considering use.
For mild to moderate depression, some studies suggest St. John's Wort can be similarly effective to certain conventional antidepressants. However, it may have a different side effect profile and significant drug interactions. This comparison does not extend to all types or severities of depression.
Scientific research indicates that St. John's Wort extracts can be effective for treating mild to moderate depression, often showing comparable efficacy to some standard antidepressants. However, results can vary depending on the extract used and the specific study design. Research on its effectiveness for other conditions is less conclusive.
For mild to moderate depression, some studies suggest St. John's Wort may be as effective as certain prescription antidepressants. However, results can vary, and it is not generally recommended as a substitute for standard care for severe depression.
Clinical studies indicate that St. John's Wort can be effective for relieving symptoms of mild depression. Its efficacy in this context has been compared to that of some conventional antidepressants. However, individual responses may vary.
schedule Dosage, timing & forms
Common dosages of St. John's Wort extract often range from 300 mg to 900 mg per day. These dosages typically provide standardized amounts of active compounds like hypericin or hyperforin. It's important to check the product label for specific recommendations.
The effects of St. John's Wort are generally not immediate and may take several weeks to become noticeable. Individuals typically report feeling benefits after two to four weeks of consistent daily use. It's important to continue taking it as directed for the recommended duration.
The effects of St. John's Wort are typically not immediate and may take several weeks to become noticeable. Individuals often report initial changes within 2 to 4 weeks, with more pronounced benefits potentially appearing after 4 to 6 weeks of consistent use. This gradual onset is common for many herbal supplements.
Common dosages for St. John's Wort extracts, often standardized to hypericin or hyperforin, typically range from 300 mg to 900 mg per day. These doses are usually divided into two or three administrations throughout the day. The specific dosage can vary based on the extract's standardization and the product's concentration.
St. John's Wort is typically taken two to three times per day. Dividing the daily dose helps maintain consistent levels of its active compounds in the body. Always follow the specific instructions provided on the supplement's label or by a qualified healthcare professional.
health_and_safety Safety & interactions
No, St. John's Wort should not be taken with antidepressant medications, especially selective serotonin reuptake inhibitors (SSRIs). Combining them can lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high fever. Always consult a healthcare professional before combining St. John's Wort with any prescription drugs.
Yes, St. John's Wort can interact significantly with many antidepressant medications. This interaction may lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high blood pressure. It is crucial to consult a healthcare professional before combining St. John's Wort with any antidepressant.
St. John's Wort can interact significantly with many medications, reducing their effectiveness or increasing side effects. Common side effects may include photosensitivity, upset stomach, fatigue, and restlessness. It is important to discuss its use with a healthcare provider.
Yes, St. John's Wort significantly interacts with medications used for HIV/AIDS (e.g., protease inhibitors, NNRTIs) and immunosuppressants used after organ transplantation (e.g., cyclosporine). It can dramatically reduce the levels and effectiveness of these critical drugs. Such combinations are generally contraindicated and should be strictly avoided.
Yes, St. John's Wort is known to reduce the effectiveness of hormonal contraceptives, including birth control pills. This interaction can potentially lead to unintended pregnancy. It is recommended to use an alternative or additional method of contraception while taking St. John's Wort.
Ingredients
| Ingredient | Amount per serving |
|---|---|
St. John's Wort (Hypericum perforatum) flowering tops extract | 1000 mg |
Categories
St. John's Wort 58.0
This product is an extract, which is a positive, but it is not specified as standardized to hypericin. Furthermore, its very high price per serving makes it a less competitive option within the St. John's Wort category.
Goals
Mood Support 60.0
The liquid extract form could lead to quicker absorption, which might be beneficial for mood support, but the absence of standardization makes consistent potency and therefore predictable effects uncertain.
Stress Relief 58.0
Its liquid form might be preferred for immediate use during stress, but without knowing the standardized active compounds, its efficacy for consistent stress relief is less assured than other extract options.
Sleep Support 55.0
The benefits for sleep are indirect. While the liquid form might allow for precise dosing before bed, the lack of standardization means its effectiveness for promoting sleep through mood improvement is not guaranteed.
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