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Detox & Liver Health

Reg'Activ
4.7
★ ★ ★ ★ ★
(175 ratings)
Selenium 100 mcg
Methionine
Milk Thistle 250 mg
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Score87

A specialized probiotic and herbal blend that supports liver detoxification and the body's natural antioxidant defense.

How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Detoxification
General Health
Immunity

Score 87

A specialized probiotic and herbal blend that supports liver detoxification and the body's natural antioxidant defense.

How scoring works
$39.96($1.33 per serving)
iHerb
$ 44.64
Pure Formulas
$ 39.96
Vitacost
$ 49.95
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Analysis

It features the ME-3 probiotic strain, which has been studied for its ability to support your body's production of glutathione. This works alongside 250 mg of milk thistle and 200 mg of NAC to support the liver's natural ability to filter and clear waste.

The formula also includes L-methionine, a sulfur-containing amino acid that supports metabolic pathways in the liver. It's a great option for those looking for a modern, probiotic-based approach to detoxification and immunity.

Pros

  • Includes the unique ME-3 probiotic strain
  • Provides 250 mg of milk thistle for liver health
  • Features NAC to support glutathione levels
  • Reasonable 100 mcg dose of selenium

Cons

  • Premium price for a 30-day supply
  • Methionine dose is quite low compared to targeted amino products
  • Probiotic focus may not be needed by everyone seeking liver support

Warnings

  • Check with a professional if you have severe digestive issues before taking probiotics
  • Best taken consistently to allow the probiotic to colonize
  • Store in a cool, dry place to ensure probiotic viability

Nutrient quality

90 Highest impact

Utilization of the patented ME-3 probiotic strain reflects a focus on high-quality, research-supported ingredients. Appropriate dosages of NAC and selenium ensure robust support for glutathione synthesis and liver health.

Ingredient transparency

93 Highest impact

Labeling provides specific quantities for all active components, including the unique probiotic count and mineral forms. Full disclosure of standardized botanical extracts helps in evaluating the formula's potency.

Customer satisfaction

86 Highest impact

High average rating and positive feedback regarding detoxification and liver health indicate a successful user experience. Although review volume is lower than some brands, the consistency of sentiment suggests efficacy.

Value for money

76 High impact

Higher price per serving is justified by the inclusion of the patented ME-3 probiotic and high-quality nutrient forms. Specialized formula design provides distinct value for users seeking targeted liver and antioxidant support.

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Goals

Detoxification
Impact
Highest effect
A+ Goal FitB+ Strength of SupportA CoverageA+ Formula Quality

Inclusion of standardized milk thistle extract and sulfur donors like n-acetyl cysteine and methionine supports both liver protection and Phase II conjugation. Selenium serves as a critical cofactor for glutathione peroxidase, enhancing antioxidant defense.

The lactobacillus fermentum ME-3 probiotic further assists by supporting glutathione status and gut-liver axis health. This multifaceted approach appears well aligned with comprehensive detoxification goals.

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General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportA- CoverageA Formula Quality

Selenium and N-acetyl-cysteine (NAC) support foundational antioxidant defense and systemic resilience by maintaining glutathione levels. Botanicals like milk thistle and specialized probiotic strains provide further support for managing metabolic stressors.

Providing 100 mcg of bioavailable selenium appears well-aligned with maintaining long-term wellness. This diverse combination supports multiple biological pathways essential for daily vitality and cellular protection.

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Immunity
Impact
High effect
B Goal FitB+ Strength of SupportC+ CoverageB+ Formula Quality

Selenium as Selenomethionine and N-Acetyl-Cysteine provide powerful support for the body's internal antioxidant networks, particularly the glutathione pathway. Selenium is a vital cofactor for enzymes that neutralize harmful oxidative stress generated during an infection.

The 100 mcg dose of selenium is safe and appropriate for daily maintenance support. This combination, which also includes a specialized probiotic strain, provides broad-spectrum support for both the gut barrier and systemic cellular defense.

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Ingredients

IngredientAmount per serving
Selenium (Selenomethionine)
 100 mcg
Lactobacillus fermentum ME-3
60 mg
Milk Thistle fruit extract
250 mg
N-Acetyl-Cysteine
200 mg
L-Methionine
50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Selenium (Selenomethionine) · 100 mcg OverallScore72
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
This detox-focused formula uses generic selenomethionine at a safe maintenance dose of 100 mcg. It provides good organic absorption, although it is an expensive way to obtain selenium as a standalone mineral.
View ingredientView products
Methionine · 50 mg OverallScore60
A- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value
This premium liver and detox formula includes a low dose of L-methionine alongside specialized probiotics. It is priced as a specialty product rather than a targeted methionine supplement.
View ingredientView products
Milk Thistle · 250 mg OverallScore50
C Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
Reg'Activ Detox & Liver Health is a specialized formula featuring the ME-3 probiotic alongside liver-supportive nutrients like methionine and milk thistle. It uses high-quality fruit-derived extracts but comes at a very high price point compared to standard milk thistle products.
View ingredientView products
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