B-12 500 mcg
21st Century
B-12 500 mcg
4.7
★ ★ ★ ★ ★
(10877 ratings)
Vitamin B12 500 mcg
Score 72.0
An incredibly affordable 500mcg cyanocobalamin B12 supplement, offering exceptional value for basic B12 needs despite its synthetic form.
Quantity: 110 Tablet(s)Servings size: 1 Tablet(s) (110 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 72.0
An incredibly affordable 500mcg cyanocobalamin B12 supplement, offering exceptional value for basic B12 needs despite its synthetic form.
insights Analysis
The 21st Century B-12 500 mcg is remarkably cost-effective, offering a foundational dose of cyanocobalamin at arguably the lowest price per serving in the market. This product is ideal for individuals looking for a simple, budget-friendly way to maintain their B12 levels. It has garnered a good number of reviews, largely reflecting satisfaction with its affordability. As with other cyanocobalamin products, it requires conversion to active forms in the body, which might not be optimal for everyone, especially those with specific metabolic needs or genetic variations. However, for general maintenance and preventing deficiency, its value proposition is hard to beat.
- Extremely low price per serving, offering exceptional affordability.
- Moderate 500 mcg dosage is suitable for daily maintenance.
- Good number of servings per bottle, providing long-term supply.
- Contains cyanocobalamin, a synthetic form of B12 that needs to be converted by the body.
- Lower dosage compared to many other B12 supplements, which might not be enough for deficiencies.
$4.48($0.04 per serving)
 Pure Formulas | $ 4.48 | |
 iHerb | $ 5.49 | |
 Amazon | $ 8.08 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B12 | 500 mcg |
Calcium | 100 mg |
Categories
Vitamin B12 72.0
As a Vitamin B12 supplement, this product excels in terms of affordability, making essential B12 supplementation accessible to a broad audience. While it offers a moderate dose of cyanocobalamin, its unparalleled price per serving makes it a strong choice for basic B12 needs.
Goals
Energy 68.0
B12 is essential for converting food into energy. This 500mcg dose is sufficient for daily energy maintenance, especially for those without severe deficiencies, but the cyanocobalamin form's conversion step might mean it's not the fastest or most direct route to an energy boost for all users.
Metabolism Boost 68.0
B12 is crucial for efficient metabolism of nutrients. The 500mcg dosage helps ensure sufficient B12 for these processes, supporting the body's ability to convert fats, carbs, and proteins into energy, though its synthetic form requires an extra step for full metabolic integration.
Mood Support 67.0
B12 contributes to the synthesis of compounds affecting mood. This product can help support mood stability through adequate B12 intake, yet the synthetic cyanocobalamin form may not provide the same direct impact on complex mood-regulating biochemical pathways as methylcobalamin.
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