BioCoenzymated Riboflavin 5'-Phosphate 50 mg
Natural Factors
BioCoenzymated Riboflavin 5'-Phosphate 50 mg
4.9
★ ★ ★ ★ ★
(7653 ratings)
Riboflavin 50 mg
Score 85.0
Natural Factors BioCoenzymated Riboflavin 5'-Phosphate provides a highly bioavailable form of Vitamin B2 at a robust 50mg dose, ideal for those seeking enhanced absorption for energy, vision, and skin health. While effective, its coenzymated form contributes to a higher price per serving.
Quantity: 30 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Energy
General Health
Vision Support
Skin Health
leaderboard Score 85.0
Natural Factors BioCoenzymated Riboflavin 5'-Phosphate provides a highly bioavailable form of Vitamin B2 at a robust 50mg dose, ideal for those seeking enhanced absorption for energy, vision, and skin health. While effective, its coenzymated form contributes to a higher price per serving.
insights Analysis
Natural Factors BioCoenzymated Riboflavin 5'-Phosphate 50 mg is formulated with Riboflavin 5-Phosphate (R-5-P), which is the active coenzyme form of vitamin B2. This form is superior to standard Riboflavin for many individuals, as it bypasses the need for enzymatic conversion in the body, ensuring more efficient absorption and utilization. This makes it particularly effective for its stated goals of energy production, as Riboflavin is a key component of FAD and FMN, coenzymes essential for the electron transport chain. Nutritionists often recommend coenzymated forms for better bioavailability, especially for those with genetic variations or health conditions that might impair this conversion. Online reviews generally praise its efficacy, with a high review count (7310) suggesting broad user satisfaction. However, the advanced form and brand reputation come at a higher price per serving ($27) compared to conventional Riboflavin supplements.
- Contains Riboflavin 5-Phosphate (R-5-P), the highly bioavailable and active coenzyme form.
- Offers a clinically relevant 50mg dose, suitable for therapeutic use or addressing specific deficiencies.
- High review count indicates widespread acceptance and positive user experiences.
- Price per serving ($27) is higher compared to standard Riboflavin alternatives.
- Only 30 servings per container, requiring more frequent repurchasing.
$8.37($0.27 per serving)
 iHerb | $ 8.37 | |
 Vitacost | $ 8.37 | |
 Amazon | $ 36.95 |
bolt Effectiveness for goals
Riboflavin is essential for cellular energy production, the metabolism of fats, and the conversion of other B vitamins into their active forms. It plays a crucial role in maintaining healthy skin, eyes, and nerve function by supporting various metabolic processes.
Some research suggests that high-dose Riboflavin supplementation may help reduce the frequency and duration of migraine attacks in certain individuals. This effect is thought to be due to its role in improving mitochondrial energy metabolism.
Riboflavin is vital for the body's energy production processes by helping convert food into usable energy. While essential for preventing fatigue due to deficiency, supplemental Riboflavin typically does not provide an 'energy boost' in individuals who are not deficient.
Riboflavin is important for normal vision and is being studied for its potential role in preventing or slowing the progression of certain eye conditions, such as cataracts. Its involvement in antioxidant pathways may help protect eye tissues from oxidative damage.
Riboflavin supplementation is highly effective in preventing and treating Riboflavin deficiency, also known as ariboflavinosis. Deficiency can lead to symptoms like sore throat, cracks at the corners of the mouth, and certain skin and eye conditions.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men is 1.3 mg per day and for adult women is 1.1 mg per day. Higher doses might be used in supplements, often ranging from 5 mg to 100 mg, depending on individual needs or specific conditions. It's best to consult a healthcare professional for personalized dosage advice.
There is no established tolerable upper intake level (UL) for Riboflavin because there is no evidence of toxicity from high intakes. Even at very high doses, excess Riboflavin is typically excreted in the urine. However, extremely high doses can sometimes lead to temporary digestive upset.
For specific conditions, such as migraine prevention, higher doses of Riboflavin are often used, typically around 400 mg per day. This specific dosage should only be taken under the guidance and supervision of a healthcare professional. These doses are significantly higher than the RDA.
Taking Riboflavin with food can enhance its absorption, particularly if the food contains protein. It is fat-soluble in some forms and its absorption is improved in the presence of food. Many recommend taking it with a meal.
Riboflavin is commonly available in supplement form as riboflavin or riboflavin 5'-phosphate (FMN). It can be found in capsules, tablets, and sometimes in liquid formulations. Riboflavin 5'-phosphate is the metabolically active form and is sometimes preferred for better absorption.
health_and_safety Safety & interactions
Riboflavin is generally considered safe for most healthy adults when taken at recommended doses. As a water-soluble vitamin, excess amounts are typically excreted in the urine. Serious adverse effects are rare.
Adequate Riboflavin intake is crucial during pregnancy and lactation for both maternal and infant health. While generally considered safe at recommended doses, pregnant or breastfeeding individuals should consult their healthcare provider before taking any new supplements. Excessively high doses are not recommended without medical supervision.
Riboflavin is generally well-tolerated, even at high doses. The most common noticeable effect is a harmless, bright yellow-orange discoloration of urine. Gastrointestinal upset is rare but possible with very high intakes.
Riboflavin (Vitamin B2) is generally considered safe when consumed in amounts found naturally in foods or from supplements at recommended doses. It is a water-soluble vitamin, meaning excess amounts are typically excreted by the body. Serious adverse effects are rare.
Since Riboflavin is water-soluble, excess amounts are primarily excreted in the urine, leading to bright yellow urine. There is no established Upper Tolerable Intake Level (UL) for Riboflavin due to its low toxicity. However, extremely high doses might rarely cause mild digestive upset.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Riboflavin | 50 mg |
Categories
Riboflavin 90.0
This product represents a high-quality option within the Riboflavin collection due to its coenzymated form, which offers superior bioavailability compared to standard Riboflavin supplements.
Goals
Energy 90.0
Riboflavin is crucial for cellular energy production, acting as a coenzyme in metabolic pathways. The coenzymated R-5-P form ensures optimal bioavailability, directly supporting the body's energy mechanisms more efficiently than standard B2.
General Health 88.0
As a fundamental B vitamin, Riboflavin supports numerous bodily functions, including antioxidant activity and cellular growth. Its readily usable form contributes significantly to overall cellular well-being.
Vision Support 85.0
Riboflavin plays a role in eye health, potentially helping to prevent cataracts and supporting general vision. The active R-5-P form ensures the body has access to this vital nutrient for ocular function.
Recommended Alternatives
92 Value 
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(275 ratings)
Offers an extremely high dosage (400mg) of standard Riboflavin at an exceptionally low price per serving ($12), providing immense value for dose for those seeking high potency.
87 Value 
Vitamin B2 250 mg
NaturesPlus
4.7
★★★★★
(323 ratings)
Provides a significantly higher standard Riboflavin dose (250mg) at a competitive price per serving ($28), offering more Riboflavin per dollar for increased needs.
80 Value 
Balance B-50 Complex Comprehensive Formula
Swanson
4.8
★★★★★
(873 ratings)
Offers 50mg of standard Riboflavin within a B-complex for $7/serving, providing good value as a general B-vitamin support with a comparable B2 dose.
95 Performance 
Migra-Eeze
Life Extension
4.5
★★★★★
(651 ratings)
Features a much higher dosage of Riboflavin 5-Phosphate (400mg), offering superior potency in the active form for specific, high-demand needs.
90 Performance 
Riboflavin Vitamin B2 400 mg
Nature's Way
4.8
★★★★★
(1549 ratings)
Provides a substantial 400mg dose of standard Riboflavin, offering higher therapeutic potential than the original for intense supplementation.
88 Performance 
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(275 ratings)
Delivers a high 400mg dose of standard Riboflavin, making it a stronger alternative for individuals requiring significantly higher amounts for therapeutic effects.
90 Budget 
R-5-P Coenzymated Vitamin B-2 50 mg
Swanson Ultra
4.8
★★★★★
(678 ratings)
Offers the same coenzymated R-5-P form and dosage (50mg) at a significantly lower price per serving ($16), making it a direct and more economical alternative.
85 Budget 
B-2 100 mg
NOW
4.8
★★★★★
(9220 ratings)
Provides a higher dosage (100mg) of standard Riboflavin at an incredibly low price per serving ($4), representing a much cheaper entry point for B2.
84 Budget 
Riboflavin 100 mg
Swanson
4.8
★★★★★
(765 ratings)
Delivers 100mg of standard Riboflavin at an exceptionally low price per serving ($4), offering substantial Riboflavin for a minimal cost.
92 Value
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(275 ratings)
Offers an extremely high dosage (400mg) of standard Riboflavin at an exceptionally low price per serving ($12), providing immense value for dose for those seeking high potency.
87 Value
Vitamin B2 250 mg
NaturesPlus
4.7
★★★★★
(323 ratings)
Provides a significantly higher standard Riboflavin dose (250mg) at a competitive price per serving ($28), offering more Riboflavin per dollar for increased needs.
80 Value
Balance B-50 Complex Comprehensive Formula
Swanson
4.8
★★★★★
(873 ratings)
Offers 50mg of standard Riboflavin within a B-complex for $7/serving, providing good value as a general B-vitamin support with a comparable B2 dose.
95 Performance
Migra-Eeze
Life Extension
4.5
★★★★★
(651 ratings)
Features a much higher dosage of Riboflavin 5-Phosphate (400mg), offering superior potency in the active form for specific, high-demand needs.
90 Performance
Riboflavin Vitamin B2 400 mg
Nature's Way
4.8
★★★★★
(1549 ratings)
Provides a substantial 400mg dose of standard Riboflavin, offering higher therapeutic potential than the original for intense supplementation.
88 Performance
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(275 ratings)
Delivers a high 400mg dose of standard Riboflavin, making it a stronger alternative for individuals requiring significantly higher amounts for therapeutic effects.