L-Tryptophan Powder
NOW
L-Tryptophan Powder
4.4
★ ★ ★ ★ ★
(525 ratings)
Tryptophan 950 mg
Score 15.0
This product offers a pure, high-dose L-Tryptophan, effective for mood, stress, and sleep support, but its value is severely diminished by an extremely high price per serving compared to readily available alternatives. The form description is inconsistent with the product name.
Quantity: 2 Liquid(s)Servings size: 2 tsp (57 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 15.0
This product offers a pure, high-dose L-Tryptophan, effective for mood, stress, and sleep support, but its value is severely diminished by an extremely high price per serving compared to readily available alternatives. The form description is inconsistent with the product name.
insights Analysis
This NOW L-Tryptophan product is presented as a straightforward, single-ingredient supplement aimed at promoting mood, alleviating stress, and supporting sleep. L-Tryptophan is an essential amino acid and a direct precursor to serotonin, a neurotransmitter crucial for mood regulation and relaxation, and subsequently to melatonin, the hormone vital for sleep induction. While the 950mg dose is therapeutically significant for these goals, aligning with common recommendations from nutritionists and scientific studies for efficacy in these areas, the product's listed pricePerServing of $13.90 for this single dose makes it prohibitively expensive when compared to other L-Tryptophan supplements on the market. Furthermore, there is a discrepancy between the product title, 'L-Tryptophan Powder,' and the listed form: Liquid(s), which, based on the instructions, leads us to assume it is a powder.
- Contains a pure, therapeutically effective dose (950mg) of L-Tryptophan, a well-researched amino acid for its role in serotonin and melatonin production.
- As a precursor to serotonin and melatonin, it directly targets the stated goals of mood support, stress relief, and sleep promotion.
- The listed price per serving of $13.90 for 950mg of L-Tryptophan is exceptionally expensive, making it a very poor value compared to other L-Tryptophan supplements.
- The product's form is inconsistently described as 'Liquid(s)' in the data while the name specifies 'Powder,' creating ambiguity.
- Lacks synergistic cofactors like Vitamin B6, Magnesium, or Niacin which are often included in more comprehensive L-Tryptophan supplements to aid conversion to serotonin.
- Individuals taking antidepressant medications (SSRIs, MAOIs) or other serotonergic drugs should consult a healthcare professional before using L-Tryptophan due to the risk of serotonin syndrome.
- May cause drowsiness; avoid operating heavy machinery or driving after taking, especially initially.
- Potential side effects include nausea, stomach upset, and dizziness in some individuals.
$13.90($0.24 per serving)
 Daily Vita | $ 13.90 | |
| Daily Vita | $ 16.00 | |
| Daily Vita | $ 16.00 | |
 Amazon | $ 20.94 | |
 Pure Formulas | $ 21.42 | |
 iHerb | $ 22.03 |
bolt Effectiveness for goals
Tryptophan is an essential amino acid that serves as the sole precursor for the synthesis of serotonin in the body. After absorption, Tryptophan is converted to 5-hydroxytryptophan (5-HTP), which then converts to serotonin. This process is crucial for various physiological functions.
Tryptophan is an essential amino acid often supplemented to support the body's natural production of serotonin and melatonin. These compounds play roles in mood regulation, sleep cycles, and overall well-being. Its use is typically aimed at supporting these physiological processes.
L-Tryptophan is an essential amino acid, meaning the body cannot produce it and it must be obtained through diet. It serves as a precursor to serotonin, a neurotransmitter involved in mood regulation, and melatonin, a hormone that regulates sleep-wake cycles. Additionally, Tryptophan is involved in the synthesis of niacin (vitamin B3).
Some research suggests that Tryptophan may support sleep by increasing the production of serotonin, which is a precursor to melatonin. Melatonin is a hormone crucial for regulating the sleep-wake cycle. While findings are mixed, some individuals report benefits in sleep latency and quality.
L-Tryptophan is converted into 5-hydroxytryptophan (5-HTP), which then becomes serotonin, and subsequently melatonin in the pineal gland. Melatonin is a key hormone that helps regulate the body's circadian rhythm and promote sleep. By providing the building blocks for melatonin, Tryptophan may contribute to sleep onset and quality.
schedule Dosage, timing & forms
L-Tryptophan dosages are generally higher (e.g., 500-2000mg) compared to 5-HTP (e.g., 50-300mg), as 5-HTP is a more direct precursor to serotonin. Both are often taken before bed for sleep or split through the day for mood support. Their absorption and potential effects can differ due to their metabolic pathways.
Typical dosages for L-Tryptophan can range from 500 mg to 2000 mg per day, often split into multiple doses. The appropriate amount can depend on individual needs and the desired effect. It's generally advisable to start with a lower dose and adjust as needed, preferably under guidance.
Typical dosages for L-Tryptophan can vary based on individual needs and the intended use. For sleep support, dosages often range from 500 mg to 2000 mg taken before bedtime. For mood support, lower doses may be taken throughout the day. It's advisable to start with a lower dose and adjust as needed, preferably under guidance.
To optimize absorption and reduce competition with other amino acids, L-Tryptophan is often recommended to be taken on an empty stomach. Alternatively, taking it with a carbohydrate-rich, protein-low snack can enhance its transport into the brain. Taking it with protein-rich meals can hinder its effectiveness.
For sleep support, L-Tryptophan is often recommended to be taken 30-60 minutes before bedtime. For other purposes, it might be taken throughout the day, sometimes between meals to aid absorption. Individual responses can vary.
health_and_safety Safety & interactions
Combining L-tryptophan with antidepressant medications, particularly SSRIs, MAOIs, or tricyclics, can significantly increase serotonin levels, potentially leading to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before combining these substances. Always seek medical advice regarding supplement and medication interactions.
Yes, L-Tryptophan can interact significantly with medications that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and MAO inhibitors. Combining Tryptophan with these drugs can potentially lead to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before taking L-Tryptophan if you are on any such medications.
Common side effects, especially at higher doses, can include mild gastrointestinal issues such as nausea, heartburn, stomach pain, and loss of appetite. Other potential effects might include drowsiness, dizziness, and dry mouth. It's generally well-tolerated when taken appropriately.
Yes, supplements that also influence serotonin levels, such as 5-HTP and St. John's Wort, should generally not be combined with L-tryptophan. This combination could also elevate the risk of serotonin syndrome. Always consult a healthcare provider for personalized advice on supplement stacking.
Individuals taking antidepressant medications (SSRIs, SNRIs, MAOIs), certain pain medications, or other drugs that affect serotonin should generally avoid L-Tryptophan due to the risk of serotonin syndrome. Pregnant or breastfeeding women, and those with pre-existing liver or kidney conditions, should also consult a healthcare provider before use. People with Eosinophilia-Myalgia Syndrome (EMS) history should also exercise caution.
Ingredients
| Ingredient | Amount per serving |
|---|---|
L-Tryptophan | 950 mg |
Categories
Tryptophan 20.0
As a pure L-Tryptophan product, it directly falls into this category and offers a potent dose of the amino acid. However, its extremely high price per serving makes it an uncompetitive and very poor choice within the Tryptophan collection when compared to other far more affordable options that offer similar or higher doses.
Goals
Mood Support 80.0
L-Tryptophan is a critical precursor to serotonin, a key neurotransmitter involved in mood regulation, making a 950mg dose effective for supporting a balanced mood. While the ingredient is well-suited, the lack of synergistic cofactors for conversion prevents a perfect score.
Stress Relief 80.0
By increasing serotonin levels, L-Tryptophan can help promote feelings of calm and relaxation, contributing to stress reduction. The dosage is adequate for this purpose, though other ingredients commonly found in stress-relief blends are absent.
Sleep Support 80.0
L-Tryptophan is converted to 5-HTP and then to serotonin, which is subsequently converted into melatonin, the primary hormone that regulates the sleep-wake cycle. A 950mg dose can effectively aid in initiating and maintaining healthy sleep patterns.
Recommended Alternatives
95 Value 
L-Tryptophan 1000 mg
AN Amazing Nutrition Amazing Formulas
4.5
★★★★★
(2545 ratings)
Offering a potent 1000mg dose at an exceptionally low price per serving (16), this product provides outstanding value, delivering more L-Tryptophan for significantly less cost compared to the analyzed product.
88 Value 
L-Tryptophan 500 mg
Doctor's Best
4.5
★★★★★
(1931 ratings)
This alternative features the high-purity TryptoPure form of L-Tryptophan at a very competitive price per serving (19), representing excellent value for a reliable and quality single-ingredient supplement.
90 Value 
Optimized Tryptophan Plus
Life Extension
4.6
★★★★★
(1307 ratings)
Despite being a more comprehensive formula with 1000mg L-Tryptophan and cofactors, its price per serving (26) is still dramatically lower than the analyzed product, offering significantly better overall value for enhanced support.
98 Performance 
New Mood
Onnit
4.2
★★★★★
(6533 ratings)
Onnit's New Mood is a comprehensive blend designed for mood and sleep, including L-Tryptophan, 5-HTP, magnesium, B vitamins, and calming herbal extracts, offering a multi-faceted approach superior to a standalone L-Tryptophan product.
95 Performance 
Serotonin Brain Food
NS Natural Stacks
4.7
★★★★★
(689 ratings)
This alternative provides a higher dose of L-Tryptophan (1250mg) along with essential co-factors like magnesium, zinc, niacin, and adaptogenic rhodiola, creating a more potent and synergistic formula for serotonin support.
90 Performance
Optimized Tryptophan Plus
Life Extension
4.6
★★★★★
(1307 ratings)
Life Extension's Optimized Tryptophan Plus offers a higher 1000mg dose of L-Tryptophan alongside niacin and L-lysine, which are important for its conversion and overall efficacy, making it a more 'optimized' choice.
95 Budget
L-Tryptophan 1000 mg
AN Amazing Nutrition Amazing Formulas
4.5
★★★★★
(2545 ratings)
This alternative offers double the dosage (1000mg) for an overwhelmingly lower price per serving (16 vs 1600), providing vastly superior value for core L-Tryptophan supplementation.
88 Budget
L-Tryptophan 500 mg
Doctor's Best
4.5
★★★★★
(1931 ratings)
Doctor's Best provides 500mg of L-Tryptophan using the high-quality TryptoPure form at a significantly lower price per serving (19 vs 1600), making it a much more accessible and reliable option.
90 Budget
Optimized Tryptophan Plus
Life Extension
4.6
★★★★★
(1307 ratings)
This alternative offers 1000mg of L-Tryptophan plus synergistic ingredients for a dramatically lower price per serving (26 vs 1600), providing a comprehensive and economical solution compared to the analyzed product.
95 Value
L-Tryptophan 1000 mg
AN Amazing Nutrition Amazing Formulas
4.5
★★★★★
(2545 ratings)
Offering a potent 1000mg dose at an exceptionally low price per serving (16), this product provides outstanding value, delivering more L-Tryptophan for significantly less cost compared to the analyzed product.
88 Value
L-Tryptophan 500 mg
Doctor's Best
4.5
★★★★★
(1931 ratings)
This alternative features the high-purity TryptoPure form of L-Tryptophan at a very competitive price per serving (19), representing excellent value for a reliable and quality single-ingredient supplement.
90 Value
Optimized Tryptophan Plus
Life Extension
4.6
★★★★★
(1307 ratings)
Despite being a more comprehensive formula with 1000mg L-Tryptophan and cofactors, its price per serving (26) is still dramatically lower than the analyzed product, offering significantly better overall value for enhanced support.
98 Performance
New Mood
Onnit
4.2
★★★★★
(6533 ratings)
Onnit's New Mood is a comprehensive blend designed for mood and sleep, including L-Tryptophan, 5-HTP, magnesium, B vitamins, and calming herbal extracts, offering a multi-faceted approach superior to a standalone L-Tryptophan product.
95 Performance
Serotonin Brain Food
NS Natural Stacks
4.7
★★★★★
(689 ratings)
This alternative provides a higher dose of L-Tryptophan (1250mg) along with essential co-factors like magnesium, zinc, niacin, and adaptogenic rhodiola, creating a more potent and synergistic formula for serotonin support.
90 Performance
Optimized Tryptophan Plus
Life Extension
4.6
★★★★★
(1307 ratings)
Life Extension's Optimized Tryptophan Plus offers a higher 1000mg dose of L-Tryptophan alongside niacin and L-lysine, which are important for its conversion and overall efficacy, making it a more 'optimized' choice.