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Abreve

Zahler
4.6
★ ★ ★ ★ ★
(2790 ratings)
European Elder 985 mg
Vitamin B5 1000 mg
Vitamin C 775 mg
Astragalus 850 mg
Product Image
Score68
A high-amount immune blend with useful vitamin C and elderberry, but weak botanical specification and excessive pantothenic acid reduce its appeal.
How scoring works
Quantity:180 Capsule(s) • (30 servings)
Goals:
Immunity
General Health
Anti-Inflammatory Support
Skin Health

Score 68

A high-amount immune blend with useful vitamin C and elderberry, but weak botanical specification and excessive pantothenic acid reduce its appeal.
How scoring works
$35.72($1.19 per serving)
Amazon
$ 35.72
iHerb
$ 35.72
Vitacost
$ 35.72
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Analysis

Vitamin C, elderberry, astragalus, echinacea, and garlic provide several complementary routes for normal immune support. The disclosed weights are substantial, so the formula is more than a token herb blend.

Botanical quality is harder to judge because species, plant parts, extraction ratios, and active-marker levels are mostly missing. The large pantothenic acid amount adds little to the main immune purpose and makes the six-capsule serving less focused.

Value is limited for ingredients that are not standardized, and the serving may be cumbersome for daily use. It fits short-term, targeted immune support better than balanced general nutrition or vision support.

Who is it for
  • Adults seeking a multi-ingredient immune formula
  • People who prefer fully disclosed active weights
Best for
  • Broad immune and antioxidant support
  • Users comfortable with a six-capsule serving

Pros

  • Substantial vitamin C amount
  • Large disclosed elderberry and herb weights
  • No proprietary active blend

Cons

  • Most botanicals lack standardization details
  • Pantothenic acid is unusually high
  • High serving burden and modest value

Warnings

  • The 1,000 mg pantothenic acid amount may cause digestive upset or loose stools.
  • Garlic may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • Astragalus and echinacea may conflict with immunosuppressant treatment.

Nutrient quality

64 Moderate impact

Several botanicals and vitamin C align with immune and antioxidant support. Unspecified extract quality and an unnecessarily aggressive pantothenic acid amount weaken the formulation.

Ingredient transparency

77 High impact

All listed actives have amounts and no proprietary blend obscures them. Botanical standardization, non-active ingredients, and complete use directions are not supplied.

Customer satisfaction

71 High impact

The average rating is strong, with a very large review count supporting the signal. No detailed reviews are supplied to assess recurring complaints or experiences tied to the intended use.

Value for money

55 Moderate impact

The formula supplies several substantial botanicals in one serving. Limited servings, basic ingredient details, and an excessive secondary nutrient reduce practical value.

Report analysis

Goals

Immunity
Impact
Highest effect
A Goal FitB+ Strength of SupportA CoverageB Formula Quality
Vitamin C · 775 mgEuropean Elder · 985 mg

Vitamin C, elderberry, astragalus, echinacea, and garlic create broad and direct immune support across antioxidant and botanical pathways. The vitamin C and elderberry amounts are substantial, while the other herbs also appear in meaningful quantities.

Missing species, extract ratios, and active-marker standardization limit confidence in several botanicals. The very large pantothenic acid amount is difficult to justify for immunity and adds unnecessary formula weight.

Study evidence
Astragalus Supportive 16 studies
European Elder Mixed 5 studies
Vitamin C Supportive 53 studies
General Health
Impact
High effect
C+ Goal FitB Strength of SupportB+ CoverageB Formula Quality
Vitamin C · 775 mg

Substantial vitamin C and elderberry amounts provide a plausible base for antioxidant and normal immune support. Astragalus, echinacea, and garlic extend the pathway coverage beyond a single nutrient.

Missing extraction ratios, botanical species, and active-marker levels make the botanical quality difficult to verify. The formula is better suited to targeted immune support than to balanced year-round coverage of general nutritional gaps.

Study evidence
European Elder Supportive 2 studies
Vitamin C Supportive 56 studies
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitB- Strength of SupportB CoverageB- Formula Quality
Vitamin C · 775 mg

Vitamin C provides a strong antioxidant base, while garlic, elderberry, astragalus, and echinacea add several immune and plant-antioxidant pathways. The formula is aimed more at broad immune support than precise control of inflammatory enzymes.

The botanical amounts are substantial, but no extracts or active-marker percentages are given, which limits form and evidence confidence. The very large pantothenic-acid amount adds little to inflammation control and may cause digestive upset or diarrhea in sensitive users.

Study evidence
Vitamin C Supportive 50 studies
Skin Health
Impact
Moderate effect
C- Goal FitC Strength of SupportD- CoverageD- Formula Quality
Vitamin C · 775 mg

Vitamin C supports collagen synthesis, while the immune botanicals offer only indirect skin relevance. Vitamin C has established skin biology, but the botanical blend lacks strong evidence for hydration, wrinkles, or barrier function.

Vitamin C is meaningfully dosed, while the unusually high pantothenic acid amount has uncertain extra skin benefit. The active amounts are clear, but the vitamin forms and botanical standardization are not disclosed.

Study evidence
Vitamin B5 Supportive 11 studies
Vitamin C Supportive 53 studies

Ingredients

IngredientAmount per serving
Astragalus
850 mg
Echinacea
565 mg
Elderberry extract
985 mg
Garlic
625 mg
Pantothenic Acid
1000 mg
Vitamin C
775 mg
Adults 18–50 Kosher
Report overview
European Elder · 985 mg OverallScore82
C- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The high elderberry extract amount is well suited to users seeking a concentrated botanical serving. The label does not disclose an extraction ratio, anthocyanin level, or full botanical species, which limits quality verification. Its cost per active weight is favorable despite the broader multi-herb formula.

Vitamin B5 · 1000 mg OverallScore64
C- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

The high pantothenic acid amount supports intensive B5 use, but the label does not identify its chemical form. The botanical-heavy formula also lacks the excipient details needed to judge purity confidently. Its cost per active amount is high for a standard, unspecified form.

Vitamin C · 775 mg OverallScore53
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Generic vitamin C supplies a direct active dose but lacks advanced delivery and full buffering. The 775 mg serving sits within the optimal range, and the listed formula avoids sugar-based fillers and artificial colors. Cost per effective amount is relatively poor for the form.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  2. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  3. The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.
    SeyedAlinaghi S; Shahidi R; Mojdeganlou H; Akhtaran FK; Maroufi SF; Maroufi SP; Mirzapour P; Karimi A; Khodaei S; Pour MM; Mehraeen E; Dadras O · Journal of health, population, and nutrition · 2024
    Systematic review28 studies pooledImmunity forVitamin C
  4. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
    Wieland LS; Piechotta V; Feinberg T; Ludeman E; Hutton B; Kanji S; Seely D; Garritty C · BMC complementary medicine and therapies · 2021
    Systematic review5 studies pooledImmunity forEuropean Elder
  5. Select Dietary Supplement Ingredients for Preserving and Protecting the Immune System in Healthy Individuals: A Systematic Review.
    Crawford C; Brown LL; Costello RB; Deuster PA · Nutrients · 2022
    Systematic review39 studies pooledImmunity forEuropean Elder
  6. Oral Astragalus (Huang qi) for preventing frequent episodes of acute respiratory tract infection in children.
    Su G; Chen X; Liu Z; Yang L; Zhang L; Stålsby Lundborg C; Wen Z; Guo X; Qin X; Liang J; Liu X · The Cochrane database of systematic reviews · 2017
    Systematic reviewImmunity forAstragalus
  7. Astragalus in the prevention of upper respiratory tract infection in children with nephrotic syndrome: evidence-based clinical practice.
    Zou C; Su G; Wu Y; Lu F; Mao W; Liu X · Evidence-based complementary and alternative medicine : eCAM · 2013
    Systematic reviewImmunity forAstragalus
  8. Astragalus mongholicus (Fisch.) Bge Improves Peripheral Treg Cell Immunity Imbalance in the Children With Viral Myocarditis by Reducing the Levels of miR-146b and miR-155.
    Zhang Z; Dai X; Qi J; Ao Y; Yang C; Li Y · Frontiers in pediatrics · 2020
    Randomized trial68 participantsImmunity forAstragalus
  9. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  10. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  11. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  12. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  13. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  14. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.
    Tiralongo E; Wee SS; Lea RA · Nutrients · 2016
    Randomized trial312 participantsGeneral Health Immunity forEuropean Elder
  15. COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
    Silveira D; Prieto-Garcia JM; Boylan F; Estrada O; Fonseca-Bazzo YM; Jamal CM; Magalhães PO; Pereira EO; Tomczyk M; Heinrich M · Frontiers in pharmacology · 2023
    Narrative reviewGeneral Health forEuropean Elder
  16. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  17. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  18. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  19. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  20. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  21. Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies.
    Sun T; Zhao R; Zhang Y; Li D; Shan X; Tang X; Zheng Y · Frontiers in pharmacology · 2025
    Meta-analysis776 participants9 studies pooledImmunity forAstragalus
  22. [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis].
    Su L; Mao JC; Gu JH · Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine · 2008
    Randomized trial43 participantsImmunity forAstragalus
  23. [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor].
    Duan P; Wang ZM · Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine · 2003
    Randomized trial120 participantsImmunity forAstragalus
  24. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis].
    Mao SP; Cheng KL; Zhou YF · Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine · 2004
    Randomized trial168 participantsImmunity forAstragalus
  25. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials
    Jessie Hawkins, Christy Baker, Lindsey Cherry, Erich Dunne · Complementary Therapies in Medicine · 2019
    Meta-analysis180 participants4 studies pooledImmunity forEuropean Elder
  26. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections
    Z Zakay-Rones, E Thom, T Wollan, J Wadstein · Journal of International Medical Research · 2004
    Randomized trial60 participantsImmunity forEuropean Elder
  27. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  28. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  29. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  30. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  31. Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation.
    Proksch E; Nissen HP · The Journal of dermatological treatment · 2009
    Randomized trialSkin Health forVitamin B5
  32. Comparative trial of 5% dexpanthenol in water-in-oil formulation with 1% hydrocortisone ointment in the treatment of childhood atopic dermatitis: a pilot study.
    Udompataikul M; Limpa-o-vart D · Journal of drugs in dermatology : JDD · 2012
    Non-randomized trial30 participantsSkin Health forVitamin B5
  33. Panthenyl triacetate transformation, stimulation of metabolic pathways, and wound-healing properties in the human skin.
    Dell'Acqua G; Schweikert K · Journal of cosmetic science · 2012
    Randomized trialSkin Health forVitamin B5
  34. Dexpanthenol modulates gene expression in skin wound healing in vivo.
    Heise R; Skazik C; Marquardt Y; Czaja K; Sebastian K; Kurschat P; Gan L; Denecke B; Ekanayake-Bohlig S; Wilhelm KP; Merk HF; Baron JM · Skin pharmacology and physiology · 2013
    Clinical trialSkin Health forVitamin B5
  35. A randomized, double-blind, placebo-controlled study of a novel pantothenic Acid-based dietary supplement in subjects with mild to moderate facial acne.
    Yang M; Moclair B; Hatcher V; Kaminetsky J; Mekas M; Chapas A; Capodice J · Dermatology and therapy · 2014
    Randomized trial48 participantsSkin Health forVitamin B5
  36. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  37. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  38. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  39. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  40. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C