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Vitamin D Supreme with Vitamin K1 and K2

Designs for Health
4.9
(238 ratings)
Vitamin D 5000 IU
Vitamin K 550 mcg
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Score87

A high-dose Vitamin D3 and K complex that supports bone density and cardiovascular integrity.

How scoring works
Quantity:180 Capsule(s)(180 servings)
Goals:
General Health
Cardiovascular Support
Anti-Inflammatory Support
Immunity
Bone Health
Testosterone Support
Heart Health
Energy
Anti-Aging

Score 87

A high-dose Vitamin D3 and K complex that supports bone density and cardiovascular integrity.

How scoring works
$109.44($0.60 per serving)
iHerb
$ 99.49
iHerb
$ 99.49
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Analysis

This practitioner-grade formula provides 5,000 IU of Vitamin D3 alongside 550 mcg of Vitamin K. This combination is often used to ensure that calcium is directed toward the bones and away from soft tissues.

The dry capsule format is straightforward but is best taken with a meal containing fat to support the absorption of these nutrients. It is a robust option for those looking to support long-term skeletal and arterial health.

Pros

  • Potent 5,000 IU dose of D3
  • Includes a large amount of Vitamin K
  • Supports calcium metabolism
  • No unnecessary fillers

Cons

  • Lacks a built-in lipid carrier
  • Higher price per serving
  • K2 subtype not specified as MK-7

Warnings

  • Take with a fat-containing meal
  • Monitor blood levels if taking daily
  • Consult a professional if on blood thinners

Nutrient quality

91 Highest impact

Cholecalciferol and vitamin K provide meaningful support for mineral metabolism and arterial health. Higher serum levels of vitamin D may be achieved through these concentrated and bioavailable dosages.

Ingredient transparency

91 Highest impact

Labeling clearly discloses the amounts of key fat-soluble vitamins for consumer safety. Missing information regarding the specific vitamin K subtype slightly reduces the precision of the ingredient profile.

Customer satisfaction

95 Highest impact

Strong ratings and a significant review volume reflect high market acceptance and trust. Consistent positive feedback suggests the formula reliably meets user expectations for its intended purpose.

Value for money

67 High impact

Price per serving is relatively high for a formula containing only two primary nutrients. Practitioner-grade status provides some justification, but more affordable alternatives exist within the category.

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Goals

Impact
Highest effect
A+ Goal FitA Strength of SupportB+ CoverageA+ Formula Quality

Cholecalciferol (5000 IU) and Vitamin K provide potent support for the cardiovascular and skeletal systems. This combination helps regulate calcium metabolism, ensuring its proper deposition in the body for long-term health.

The therapeutic doses are robust and suitable for individuals requiring higher maintenance levels of these nutrients. This high-quality formulation avoids unnecessary additives and aligns with professional nutritional standards.

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Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA+ Formula Quality

Vitamin D3, Vitamin K1, and Vitamin K2 are combined to provide targeted support for arterial health and calcium management. The inclusion of Vitamin K2 as MK-7 is particularly relevant for preventing vascular calcification.

High-dose Vitamin D3 supports endothelial function and overall cardiac wellness. This synergistic combination is well-aligned with modern cardiovascular health strategies.

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Impact
Highest effect
A Goal FitA Strength of SupportB CoverageA+ Formula Quality

A potent dose of Vitamin D3 provides significant support for immunomodulation and the regulation of pro-inflammatory pathways. The addition of Vitamin K assists in systemic calcium balance and supports cardiovascular health alongside the primary nutrient.

Providing 5,000 IU addresses therapeutic needs for those requiring more intensive support for deficiency or immune balance. This logically constructed formula uses high-quality forms to ensure physiological activity across multiple target systems.

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Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality

High-dose Vitamin D3 is paired with Vitamin K to support immune modulation and calcium homeostasis. This combination is particularly effective for individuals seeking therapeutic replenishment of Vitamin D levels to support respiratory and systemic health.

The 5,000 IU dose is well-aligned with clinical protocols for achieving optimal serum levels. The dry capsule format necessitates consumption with a fat-containing meal to ensure proper absorption of these fat-soluble nutrients.

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Impact
Highest effect
A+ Goal FitB+ Strength of SupportC CoverageA+ Formula Quality

This high-potency supplement provides Vitamin D3 and Vitamin K to facilitate the transport and deposition of calcium into the bone matrix. This signaling pathway is critical for maintaining bone mineral density and preventing arterial calcification.

The dosages are therapeutic and well aligned with clinical recommendations for skeletal support. While it lacks structural minerals, it appears well aligned as a regulatory companion to mineral-rich diets or supplements.

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Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA Formula Quality

Vitamin D3 and vitamin K are combined to provide high-potency support for pro-hormone status. A 5000 IU dose of cholecalciferol is highly effective for raising serum levels and supporting Leydig cell function.

Cholecalciferol is the preferred form for efficacy in endocrine regulation. Capsules should be consumed with a fat-containing meal to ensure proper absorption of these fat-soluble vitamins.

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Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
5000 IU
Vitamin K
550 mcg
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD+ Value
This professional-grade supplement offers a potent dose of Vitamin D3 paired with Vitamin K for enhanced bone and cardiovascular support. While the dose is highly effective, the capsule form requires consumption with a fat-containing meal for optimal uptake.
Vitamin K · 550 mcg OverallScore33
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD+ Value
This vitamin supplement provides Vitamin K in the MK-4 and K1 forms, which are beneficial for clotting and bone mineralization. It lacks the long-acting MK-7 form and a built-in lipid carrier for optimal fat-soluble absorption.
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