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Valerian

notesDescription

Valerian is a perennial flowering plant native to Europe and Asia, whose roots have been utilized for centuries as a traditional herbal remedy. It is predominantly known for its mild sedative effects, making it a popular natural choice for individuals seeking to enhance sleep onset and duration, as well as manage occasional feelings of nervousness or mild stress. The therapeutic actions of Valerian are believed to stem from its diverse array of bioactive compounds, including valerenic acid, iridoids (like valepotriates), and various flavonoids. These constituents are thought to interact with gamma-aminobutyric acid (GABA) receptors in the brain, a key neurotransmitter that helps to regulate nerve impulses. This interaction facilitates a calming effect on the central nervous system, often compared to the action of some conventional anxiolytic medications but typically with a milder impact. Historically, Valerian was applied to a range of conditions, from insomnia to digestive discomfort. In contemporary practice, its primary applications are centered on its anxiolytic (anxiety-reducing) and hypnotic (sleep-inducing) properties. It is frequently employed as a sleep aid or to mitigate symptoms of daily stress, contributing to overall mental relaxation without commonly leading to residual drowsiness upon waking when used as directed.

ecoSources
Valerian plant (Valeriana officinalis) root
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scheduleTiming & Intake
schedulePre Bedlocal_drinkTake with Water, preferably 30 minutes to 2 hours before bedtime for sleep support.
infoOften taken in the evening or shortly before bedtime for its calming and sleep-inducing effects. For general anxiety, it can be taken during the day, though potential drowsiness should be considered.
check_circleOptimal Dosage
Minimum400 mg
Maximum900 mg
report_problemSafety & Toxicity
track_changesGoals
Mood Support
sentiment_satisfied_altMood Support
Impact
Situational effect
Typical dose:300–900 mg
Valerian root acts on GABA receptors in the brain, helping to calm the nervous system, reduce anxiety, and ease the transition into sleep. By addressing sleep disturbances and nervous tension, it provides indirect but significant support for emotional well-being.
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Sleep Support
bedtimeSleep Support
Impact
Situational effect
Typical dose:300–900 mg
Valerian root is thought to work by increasing levels of the calming neurotransmitter GABA in the brain. While clinical evidence is mixed, it has a long history of use as a mild sedative. Its effectiveness can be highly individual, but for those it works for, it can be a useful tool for improving sleep latency.
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Stress Relief
self_improvementStress Relief
Impact
Situational effect
Typical dose:300–600 mg
Valerian root contains compounds that interact with GABA receptors in the brain. This interaction helps to calm the nervous system, reduce the time it takes to fall asleep, and improve sleep quality for those whose minds race at night due to stress.
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sync_altInteractions

add_circle_outlinePositive Interactions

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Melatonin
Both ingredients promote sleep; Valerian can enhance the calming effect, while Melatonin regulates sleep cycles, potentially leading to more effective sleep support.
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GABA
Valerian is believed to influence GABA receptors; supplementing with GABA may support this mechanism, potentially enhancing relaxation and anxiolytic effects.
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Magnesium
Magnesium contributes to muscle relaxation and nerve function, which can complement Valerian's calming properties, aiding in overall relaxation and sleep.

remove_circle_outlineNegative Interactions

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Caffeine
Caffeine is a stimulant and directly counteracts the sedative effects of Valerian, making Valerian less effective for relaxation or sleep.
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St. John's Wort
Combining Valerian with St. John's Wort may lead to excessive sedation or unpredictable effects due to their overlapping central nervous system activity and St. John's Wort's complex interactions.
analyticsProduct stats
sellPrice per product
Average$18.02
Median$17.02
restaurantPrice per serving
Average$0.45
Median$0.36
sciencePrice per 100 mg
Average$0.37
Median$0.21
bar_chartPrice distribution
bar_chartPrice per serving distribution
bar_chartPrice per 100 mg
Reference amount: 100 mg
categoryForms
bar_chartPaired ingredients
water_dropIngredient forms
category Valerenic Acid (11) 90
Valerenic acids represent a class of sesquiterpenoids found in Valeriana officinalis, crucial for the plant's anxiolytic and sedative effects. Extracts are often standardized to contain a certain percentage of these compounds, indicating potency. They are thought to modulate GABA-A receptors, contributing to their calming properties.
thumb_upPros
  • Represents a standardized active complex for Valerian extracts
  • Well-recognized markers for product quality and potency
  • Associated with the main pharmacological effects of Valerian
thumb_downCons
  • Focuses only on one class of compounds, potentially overlooking other beneficial constituents in whole Valerian
  • Specific individual roles of each valerenic acid are still being researched
sellPer product
Avg$33.21
Med$34.49
restaurantPer serving
Avg$0.86
Med$0.66
science Per 100 mg
Avg$0.49
Med$0.27
Price distribution
category Valerenic Acids (6) 90
Valerenic acids represent a class of sesquiterpenoids found in Valeriana officinalis, crucial for the plant's anxiolytic and sedative effects. Extracts are often standardized to contain a certain percentage of these compounds, indicating potency. They are thought to modulate GABA-A receptors, contributing to their calming properties.
thumb_upPros
  • Represents a standardized active complex for Valerian extracts
  • Well-recognized markers for product quality and potency
  • Associated with the main pharmacological effects of Valerian
thumb_downCons
  • Focuses only on one class of compounds, potentially overlooking other beneficial constituents in whole Valerian
  • Specific individual roles of each valerenic acid are still being researched
sellPer product
Avg$20.49
Med$16.68
restaurantPer serving
Avg$0.41
Med$0.41
science Per 100 mg
Avg$0.17
Med$0.16
Price distribution
category Valeric Acid (1) 35
Valeric acid (pentanoic acid) is a saturated fatty acid found in Valerian root, particularly in the essential oil. While historically thought to contribute to Valerian's calming effects, modern research suggests its primary role is in giving Valerian its characteristic strong smell. Its direct pharmacological activity as a primary mediator of sleep and stress relief is not as well-supported as that of the valerenic acids.
thumb_upPros
  • Contributes to the characteristic aroma of Valerian, a traditional marker
  • May have some minor synergistic effects within the whole plant extract
thumb_downCons
  • Not considered a primary active compound for Valerian's sedative or anxiolytic effects
  • Its direct therapeutic impact is less understood compared to valerenic acids
  • Responsible for the unpleasant odor sometimes associated with Valerian
sellPer product
Avg$18.26
Med$18.26
restaurantPer serving
Avg$0.60
Med$0.60
science Per 100 mg
Avg$0.30
Med$0.30
Price distribution

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