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Bromelain 500 mg

California Gold Nutrition
4.7
★ ★ ★ ★ ★
(6377 ratings)
Bromelain 500 mg
Product Image
Score80
A simple, strong-value 500 mg bromelain capsule whose main limitation is missing enzyme activity data.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
Digestive Health
Anti-Inflammatory Support
Joint Health

Score 80

A simple, strong-value 500 mg bromelain capsule whose main limitation is missing enzyme activity data.
How scoring works
$15.16($0.16 per serving)
Amazon
$ 35.90
iHerb
$ 15.16
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Analysis

Bromelain is the only active and provides 500 mg per capsule. The focused design avoids token additions and makes the intended enzyme easy to identify.

Bromelain quality is determined by enzyme activity as well as weight. No activity units are supplied, so the substantial milligram amount cannot confirm how strongly the capsule performs.

A 90-serving bottle and low serving cost offer strong value and convenience. It fits users who specifically want bromelain and accept the missing potency specification.

Who is it for
  • Adults seeking a focused bromelain supplement
  • Value-conscious single-enzyme users
Best for
  • One-ingredient bromelain use
  • Convenient 90-serving supply

Pros

  • 500 mg bromelain
  • Single-active formula
  • One-capsule serving
  • Strong value

Cons

  • No activity units
  • No complementary digestive enzymes
  • Potency cannot be compared precisely
  • Not suitable for pineapple allergy

Warnings

  • Bromelain may add to bleeding tendency with anticoagulant or antiplatelet medicines, especially around a procedure.
  • Bromelain may trigger reactions in people with pineapple allergy.

Nutrient quality

83 Highest impact

A substantial standalone bromelain weight is disclosed, but activity units, botanical source, and release details are missing. The supplied amounts support practical use for the intended purpose.

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Ingredient transparency

75 High impact

The active weights are clearly listed, making the core formula possible to assess. Activity units, intake timing, and non-active ingredients are absent from the supplied data.

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Customer satisfaction

71 High impact

The supplied average is very strong and the response volume is large. No detailed feedback is provided to assess recurring complaints or fit with the intended purpose.

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Value for money

91 Highest impact

Ingredient quality and serving efficiency support strong practical value. The formula compares favorably with many category alternatives.

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Goals

Digestive Health
Impact
High effect
B- Goal FitC Strength of SupportD- CoverageA- Formula Quality
Bromelain · 500 mg

Bromelain is directly relevant to protein digestion and may reduce discomfort linked to protein-heavy meals. The 500 mg capsule supplies a substantial enzyme weight in a simple formula.

Confidence in digestive potency is limited because no GDU or MCU activity units, meal-timing directions, or enzyme-protective delivery details are provided. Bromelain may raise bleeding risk with anticoagulant or antiplatelet medicines and may trigger reactions in people allergic to pineapple.

Study evidence
Bromelain Supportive 2 studies
Anti-Inflammatory Support
Impact
Moderate effect
B- Goal FitC- Strength of SupportD- CoverageB+ Formula Quality

The substantial bromelain amount may support acute swelling and tissue comfort through proteolytic enzyme activity. Its role is more situation-specific than broad daily inflammatory support.

The label gives only weight and does not state enzyme activity units, so true potency cannot be confirmed. Missing source, timing, and delayed-release details further limit confidence in systemic use.

Study evidence
Bromelain Supportive 12 studies
Joint Health
Impact
Moderate effect
C Goal FitD Strength of SupportD- CoverageA- Formula Quality

Bromelain may support joint comfort through proteolytic and inflammation-modulating effects. Human evidence is limited and depends strongly on enzyme activity, which is not disclosed.

The 500 mg weight appears substantial, but no GDU or FIP activity value is provided, so functional potency cannot be determined. Bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines and may trigger reactions in people allergic to pineapple.

Study evidence
Bromelain Mixed 5 studies

Ingredients

IngredientAmount per serving
Bromelain
500 mg
Gluten Free Adults 18–50
Report overview
Bromelain · 500 mg OverallScore53
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyA+ Value

The standalone capsule supplies a substantial 500 mg bromelain dose with excellent cost efficiency. Enzyme activity units are absent, so the true potency cannot be confirmed from weight alone. Source, timing, and delayed-release details are also missing, limiting confidence for systemic use.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  2. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  3. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  4. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  5. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  6. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  7. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  8. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  9. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  10. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  11. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  12. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain