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Meta-C 1000 mg Tablets

NutriBiotic Immunity
4.9
★ ★ ★ ★ ★
(391 ratings)
Vitamin C 1000 mg
Product Image
Score82
A transparent 1,000 mg vitamin C tablet with metabolites, calcium, and spirulina. The extras are clearly listed but may not add much practical benefit.
How scoring works
Quantity:250 Tablet(s) • (250 servings)
Goals:
Anti-Inflammatory Support
General Health
Immunity
Skin Health
Vision Support

Score 82

A transparent 1,000 mg vitamin C tablet with metabolites, calcium, and spirulina. The extras are clearly listed but may not add much practical benefit.
How scoring works
$29.80($0.11 per serving)
Vitacost
$ 39.75
iHerb
$ 29.80
Vitacost
$ 39.75
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Analysis

A 1,000 mg vitamin C amount provides substantial support for antioxidant defenses, collagen formation, and normal immune function. The label also lists dehydroascorbic acid and related metabolites rather than hiding them in an unnamed blend.

Calcium contributes 128 mg, and spirulina adds a secondary whole-food component. Neither materially changes the product's primary role as a vitamin C supplement.

The tablet is convenient and the active details are relatively transparent. A full gram may be more than some users need at once, while the specialized Meta-C components offer uncertain practical advantage over simpler forms.

Who is it for
  • Adults seeking a high-dose vitamin C tablet
  • Users interested in vitamin C metabolites
  • People who prefer disclosed companion ingredients
Best for
  • Focused antioxidant support
  • Convenient one-tablet use
  • Vitamin C with a modest calcium contribution

Pros

  • Substantial vitamin C amount
  • Metabolites and calcium are quantified
  • Coherent, easy-to-assess formula

Cons

  • Specialized delivery advantage is unclear
  • Adds 128 mg calcium
  • One-gram serving may be excessive for some users

Warnings

  • A 1,000 mg vitamin C serving may cause stomach upset or loose stools in sensitive users.
  • Include the 128 mg calcium contribution when tracking total calcium intake.

Nutrient quality

87 Highest impact

The calcium-based complex and named vitamin C metabolites may support gentler delivery than plain ascorbic acid. The vitamin C amount is substantial and well targeted for a high-potency supplement.

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Ingredient transparency

81 Highest impact

Vitamin C, metabolites, calcium, and spirulina each have specific listed amounts. A complete inactive ingredient list was not supplied.

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Customer satisfaction

68 High impact

The available aggregate rating is strong for this category. No firsthand outcome details were supplied, so alignment with the intended use is uncertain.

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Value for money

88 Highest impact

The specialized complex and meaningful amount provide strong quality for the serving cost. The product remains competitive among specialized buffered vitamin C options.

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Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB CoverageA+ Formula Quality
Vitamin C · 112 mg

Vitamin C and its metabolites provide strong antioxidant support, while spirulina adds a secondary antioxidant pathway. The combination is more advanced than plain ascorbic acid but still does not directly cover fatty-acid resolution or inflammatory enzymes.

The vitamin C amount reaches the preferred range and every component of the branded complex is quantified. Calcium-based delivery may improve tolerance, giving the formula strong dose and disclosure quality without a crowded label.

Study evidence
Vitamin C Supportive 50 studies
General Health
General Health
Impact
Highest effect
A Goal FitA+ Strength of SupportB- CoverageA- Formula Quality
Vitamin C · 112 mg

The buffered Meta-C complex supplies a well-targeted vitamin C amount with clearly quantified metabolites and calcium. Its lower-acidity design may suit users who find plain ascorbic acid uncomfortable.

Spirulina adds some complexity without a clear role in the product’s main vitamin C purpose. The formula offers strong focused support but still covers fewer foundational pathways than a broad nutrient product.

Study evidence
Vitamin C Supportive 56 studies
Immunity
Immunity
Impact
High effect
B Goal FitB+ Strength of SupportC CoverageC+ Formula Quality
Vitamin C · 112 mg

The formula supplies a substantial vitamin C amount with calcium, vitamin C metabolites, and spirulina. Vitamin C provides the strongest established contribution through collagen formation, antioxidant defense, and normal immune function.

The branded Meta-C complex makes the exact purpose of the added metabolites and spirulina less clear than a simple vitamin label. The large vitamin C amount may cause digestive upset, and sustained high intake may be unsuitable for people prone to oxalate kidney stones.

Study evidence
Vitamin C Supportive 53 studies
Skin Health
Skin Health
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageC Formula Quality
Vitamin C · 112 mg

1,000 mg of Meta-C provides a meaningful collagen cofactor with named metabolites that may support vitamin C handling. The formula remains centered on vitamin C rather than direct structural or hydration support.

The active amount and Meta-C composition are disclosed with useful detail. Spirulina adds little clearly established skin benefit, so pathway breadth remains limited.

Study evidence
Vitamin C Supportive 53 studies
Vision Support
Vision Support
Impact
High effect
C+ Goal FitA- Strength of SupportD+ CoverageB Formula Quality
Vitamin C · 112 mg

A substantial vitamin C complex supports antioxidant protection in ocular tissues. Spirulina adds carotenoid-containing material, but the label does not quantify lutein or zeaxanthin.

The Meta-C complex and active metabolites are disclosed, although their specific advantage for vision is uncertain. The formula remains mainly an antioxidant product rather than comprehensive eye support.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Meta-C)
 1000 mg
Calcium (Meta-C)
 128 mg
Biologically Active Metabolites and Dehydroascorbic Acid (Meta-C)
 112 mg
Spirulina (Meta-C)
 310 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Vitamin C (Meta-C) · 1000 mg OverallScore96
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The calcium-based Meta-C complex includes vitamin C metabolites and appears designed for gentler delivery than plain ascorbic acid. Its vitamin C amount sits in the preferred range, while the active components are clearly quantified. The branded complex is also delivered at a notably low cost per gram.

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Loading alternative details
89 Performance

Pure Buffered Calcium Ascorbate

NOW
A more performance-focused option combines 890 mg of vitamin C as Calcium Ascorbate with 100 mg of Calcium. Compared with the original's 1,000 mg of vitamin C as Meta-C, the smaller amount favors moderate daily use but provides less vitamin C per serving.
88 Performance

Buffered Gold C

California Gold Nutrition
A more performance-focused option combines 1,000 mg of vitamin C as Sodium Ascorbate with a focused single-nutrient formula. The amount matches the original, while Sodium Ascorbate replaces Meta-C and gives users a different disclosed form.
85 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
A more performance-focused option combines 1,000 mg of vitamin C as Ester-C with 108 mg of Calcium and 200 mg of Citrus Bioflavonoids Complex. The amount matches the original, while Ester-C replaces Meta-C and gives users a different disclosed form.
86 Budget

C

Swanson
The lower serving cost still provides 1,000 mg of vitamin C as Calcium Ascorbate with 120 mg of Calcium and 200 mg of Bioflavonoids. The amount matches the original, while Calcium Ascorbate replaces Meta-C and gives users a different disclosed form.
87 Budget

Pure Buffered Magnesium Ascorbate

NOW
The lower serving cost still provides 820 mg of vitamin C as Magnesium Ascorbate with 60 mg of Magnesium. Compared with the original's 1,000 mg of vitamin C as Meta-C, the smaller amount favors moderate daily use but provides less vitamin C per serving.
88 Budget

Sodium Ascorbate Capsules

NutriBiotic Immunity
The lower serving cost still provides 850 mg of vitamin C as Sodium Ascorbate with a focused single-nutrient formula. Compared with the original's 1,000 mg of vitamin C as Meta-C, the smaller amount favors moderate daily use but provides less vitamin C per serving.
85 Value

C-500 With Rose Hips

NOW
The favorable serving cost pairs 500 mg of vitamin C as Ascorbic Acid with 40 mg of Rose Hips powder. Compared with the original's 1,000 mg of vitamin C as Meta-C, the smaller amount favors moderate daily use but provides less vitamin C per serving.
88 Value

Sodium Ascorbate

NutriBiotic Immunity
The favorable serving cost pairs 1,100 mg of vitamin C as Sodium Ascorbate with a focused single-nutrient formula. Compared with the original's 1,000 mg of vitamin C as Meta-C, the larger disclosed amount may better fit users seeking higher-potency vitamin C.
87 Value

100% Pure Vitamin C Powder

Swanson Premium Brand
The favorable serving cost pairs 1,000 mg of vitamin C as Ascorbic Acid with a focused single-nutrient formula. The amount matches the original, while Ascorbic Acid replaces Meta-C and gives users a different disclosed form.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  2. Vitamin C and postoperative outcomes following mandibular third molar extraction: a randomized split-mouth study.
    Demirel M; Aktas A; Kizil M; Yalcin N · Oral surgery, oral medicine, oral pathology and oral radiology · 2026
    Randomized trial56 participantsSkin Health forVitamin C
  3. Vitamin C for the management of COVID-19: a systematic review and meta-analysis of randomized controlled trials.
    Abid H; Mushtaq I; Munir ABI; Shakil J; Vinjamuri S; Tadasare N; Kiran F; Muhammad Wali Mirza A; Fatima Khidri F; Shahid A; Ayyan M; Ehsan M; Cheema HA; Alsubari AMA; Sahra S; Siddiqi NI · Annals of medicine and surgery (2012) · 2026
    Meta-analysis9 studies pooledImmunity forVitamin C
  4. Association between hemoglobin A1c, Vitamin C, and microbiome in diabetic foot ulcers and intact skin: A cross-sectional study.
    Tong KPS; Green SJ; Ortiz J; Wu SC · Health science reports · 2024
    Cross-sectional study42 participantsSkin Health forVitamin C
  5. Immunocompetence and oxidant defense during ascorbate depletion of healthy men.
    Jacob RA; Kelley DS; Pianalto FS; Swendseid ME; Henning SM; Zhang JZ; Ames BN; Fraga CG; Peters JH · The American journal of clinical nutrition · 1992
    Clinical trial8 participantsImmunity forVitamin C
  6. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  7. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  8. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  9. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  10. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  11. Intake of vitamin C, vitamin E, selenium, zinc and polyunsaturated fatty acids and upper respiratory tract infection-a prospective cohort study.
    Raposo SE; Fondell E; Ström P; Bälter O; Bonn SE; Nyrén O; Plymoth A; Bälter K · European journal of clinical nutrition · 2018
    Cohort study1,533 participantsImmunity forVitamin C
  12. Comparison of the Efficacy of Intralesional Ascorbic Acid Mesotherapy and Intralesional Tranexamic Acid in Treating Melasma in the Skin of Colour Population.
    Aslam H; Muhammad A; Ullah A; Aziz N; Lakhiar JA; Ahmad B; Shahzadi A; Ahmad A; Chandni; Virdi G · Cureus · 2025
    Randomized trial110 participantsSkin Health forVitamin C
  13. Efficacy and Safety of tranexamic acid versus vitamin c after microneedling in treatment of melasma: Clinical and Dermoscopic study.
    El Attar Y; Doghaim N; El Far N; El Hedody S; Hawwam SA · Journal of cosmetic dermatology · 2022
    Randomized trial20 participantsSkin Health forVitamin C
  14. Dietary intake and supplement use of vitamins C and E and upper respiratory tract infection.
    Fondell E; Bälter O; Rothman KJ; Bälter K · Journal of the American College of Nutrition · 2012
    Cohort study1,509 participantsImmunity forVitamin C
  15. Comparative Evaluation of Locally Injected Dexamethasone with and Without Vitamin C in Mandibular Fractures: A Randomized Controlled Trial.
    Chincholkar A; Rudagi BM; Setiya S; Sakhariya S · Journal of maxillofacial and oral surgery · 2025
    Randomized trial30 participantsSkin Health forVitamin C
  16. Vitamin C supplementation and salivary immune function following exercise-heat stress.
    Carrillo AE; Murphy RJ; Cheung SS · International journal of sports physiology and performance · 2009
    Randomized trial12 participantsImmunity forVitamin C
  17. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage.
    Fitzpatrick RE; Rostan EF · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2002
    Non-randomized trial10 participantsSkin Health forVitamin C
  18. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  19. Split-Face Comparative Analysis Of Micro-Needling With Tranexamic Acid Vs Vitamin C Serum In Melasma.
    Raza MH; Iftikhar N; Anwar A; Mashhood AA; Tariq S; Bin Hamid MA · Journal of Ayub Medical College, Abbottabad : JAMC · 2022
    Non-randomized trial30 participantsSkin Health forVitamin C
  20. The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.
    SeyedAlinaghi S; Shahidi R; Mojdeganlou H; Akhtaran FK; Maroufi SF; Maroufi SP; Mirzapour P; Karimi A; Khodaei S; Pour MM; Mehraeen E; Dadras O · Journal of health, population, and nutrition · 2024
    Systematic review28 studies pooledImmunity forVitamin C
  21. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  22. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  23. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  24. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  25. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  26. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  27. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  28. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  29. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  30. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  31. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  32. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  33. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  34. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  35. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  36. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  37. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  38. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  39. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C