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SAMe 200 mg

Metabolic Maintenance
4.5
★ ★ ★ ★ ★
(30 ratings)
SAMe 200 mg
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Score60

A 200 mg starting amount offers narrow methylation support, but the SAMe form, net active yield, and protection from acid or moisture are unclear. Those gaps combine with weak value.

How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 60

A 200 mg starting amount offers narrow methylation support, but the SAMe form, net active yield, and protection from acid or moisture are unclear. Those gaps combine with weak value.

How scoring works
$70.00($1.16 per serving)
Pure Formulas
$ 70.00
iHerb
$ 70.00
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Analysis

The capsule lists 200 mg of SAMe, a common starting amount for a focused methyl-donor supplement. Small amounts of calcium and magnesium do not materially broaden the formula's detoxification role.

SAMe can support methylation used in Phase II conjugation, but this product covers only one part of liver and antioxidant metabolism. The label does not identify a stabilized salt or clarify whether the stated amount represents net active SAMe.

A standard capsule with no stated acid protection or moisture-protective packaging raises concern about delivery and stability. The high cost relative to the disclosed active amount further weakens the case for routine use.

Who is it for
  • Adults specifically directed toward a low SAMe starting amount
  • People focused on methylation support
  • Users able to verify storage and formulation details
Best for
  • Low starting amounts of SAMe
  • Narrow methyl-donor support
  • Clinician-guided use when formulation details are acceptable

Pros

  • Common 200 mg starting amount
  • One capsule per serving
  • Includes clearly named mineral forms
  • Focused methyl-donor role

Cons

  • Stabilized SAMe salt is not identified
  • No stated acid protection
  • Net active SAMe amount is unclear
  • No stated moisture-protective packaging
  • Weak value for the disclosed amount

Warnings

  • SAMe may trigger agitation or mania in people with bipolar disorder.
  • SAMe can compound serotonergic effects from antidepressants and other serotonergic medicines; clinician-guided use is important.

Nutrient quality

70 High impact

<p>The SAMe amount is a practical starting serving and directly fits detoxification support. Missing salt stabilization and acid protection limit likely delivery.</p>.

Ingredient transparency

72 High impact

<p>All listed amounts are disclosed without a hidden blend. Salt form, net active SAMe, intake directions, excipients, and protective packaging are unclear.</p>.

Customer satisfaction

56 Moderate impact

<p>The supplied average rating is strong and comes from a very small rating pool. No firsthand experiences or recurring complaint details were provided, so consistency remains uncertain.</p>.

Value for money

35 Lower impact

<p>The starting amount offers poor value because the serving cost is high. Uncertain stability and delivery further weaken competitiveness.</p>.

Report analysis

Goals

Detoxification
Impact
Moderate effect
C+ Goal FitD- Strength of SupportF CoverageB Formula Quality

SAMe provides a direct methyl donor used in Phase II conjugation. The product supports one narrow pathway rather than broad liver, gut, or antioxidant coverage.

The 200 mg amount is a common starting level, but the label does not identify a stabilized salt or net active amount. A standard capsule without stated acid protection creates substantial delivery uncertainty.

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Ingredients

IngredientAmount per serving
Calcium (Calcium Citrate)
 20 mg
Magnesium (Magnesium Bisglycinate)
 20 mg
SAMe
200 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
SAMe · 200 mg OverallScore34
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

The 200 mg amount is a common starting dose, but the label does not identify a stabilized salt. A standard capsule provides no stated acid protection, and the single listed weight leaves net active SAMe unclear. High normalized cost and no disclosed foil blister packaging make the delivery poor value.

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