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Calcium 1200 mg plus D3 5000 IU

Nature's Truth
4.6
★ ★ ★ ★ ★
(2258 ratings)
Vitamin D 5000 IU
Calcium 1200 mg
Product Image
Score72
Concentrated calcium and vitamin D3 may fit a supervised high-need situation, but the serving is too aggressive for routine self-directed maintenance. Calcium carbonate and the narrow active profile add further limitations.
How scoring works
Quantity:120 Softgel(s) • (60 servings)
Goals:
General Health
Bone Health
Anti-Aging
Immunity
Testosterone Support

Score 72

Concentrated calcium and vitamin D3 may fit a supervised high-need situation, but the serving is too aggressive for routine self-directed maintenance. Calcium carbonate and the narrow active profile add further limitations.
How scoring works
$14.49($0.24 per serving)
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$ 14.49
Walmart
$ 14.49
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$ 15.95
Amazon
$ 14.49
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Analysis

The two-softgel serving combines 1,200 mg of calcium carbonate with 5,000 IU of vitamin D3. Both amounts are high enough to require a clear reason for use and careful accounting of food, fortified products, and other supplements.

Vitamin D3 is provided as cholecalciferol in a fat-containing softgel, which suits absorption. Calcium carbonate is best taken with food and may be less comfortable or less reliably absorbed than citrate for some users.

The concentrated serving can be useful when a clinician has identified a substantial need. It is not a balanced general-health formula, and unsupervised long-term use raises avoidable concerns about excessive calcium and vitamin D intake.

Who is it for
  • Adults using high-dose calcium and vitamin D under guidance
  • People with a documented need for concentrated bone support
  • Users who prefer softgels and can take calcium with food
Best for
  • Clinician-guided high-dose bone support
  • Concentrated calcium and vitamin D3
  • A two-softgel serving

Pros

  • Provides clearly disclosed calcium and vitamin D3 amounts
  • Uses cholecalciferol for vitamin D3
  • Includes fat in the softgel serving
  • Delivers both core actives in two softgels

Cons

  • The 5,000 IU vitamin D3 amount is high for routine maintenance
  • The 1,200 mg calcium serving is also large
  • Uses calcium carbonate rather than citrate
  • The narrow formula does not match its broad goal list

Warnings

  • The combination of 5,000 IU vitamin D3 and 1,200 mg calcium may raise blood calcium and kidney-stone risk when total intake is already high.
  • People with kidney disease, high blood calcium, or parathyroid conditions, or those using thiazide diuretics, should use this combination only with clinical guidance.
  • Calcium carbonate should generally be taken with food and must be separated as directed from levothyroxine, iron, and certain antibiotics.

Nutrient quality

65 Moderate impact

Substantial calcium and vitamin D3 directly target bone support. The vitamin D amount is excessive for routine self-directed use and the calcium form is basic.

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Ingredient transparency

80 Highest impact

Both active amounts and forms are clearly stated without a proprietary blend. Inactive ingredients and complete use directions are not supplied.

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Customer satisfaction

70 High impact

The supplied average rating is strong. The large review count makes the rating relatively reliable.

.

Value for money

71 High impact

The focused formula is inexpensive and avoids unnecessary extras. An excessive vitamin D amount sharply reduces practical value for routine use.

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Goals

General Health
Impact
Highest effect
A Goal FitB Strength of SupportC+ CoverageA Formula Quality
Vitamin D · 5000 IU

Calcium and vitamin D3 form a coherent combination for skeletal maintenance and normal calcium regulation. Fat in the softgel may support absorption of vitamin D3.

The 1200 mg calcium and 5000 IU vitamin D3 serving is substantial and may exceed routine needs when diet and other supplements are counted. Long-term high vitamin D intake can raise calcium levels, so ongoing use is better matched to measured need.

Study evidence
Vitamin D Supportive 115 studies
Bone Health
Impact
Highest effect
A+ Goal FitB- Strength of SupportC+ CoverageA Formula Quality
Calcium · 1200 mgVitamin D · 5000 IU

Calcium and vitamin D3 create a direct and evidence-based bone pairing. The softgel supports vitamin D absorption, but calcium carbonate is less versatile than citrate.

Both doses are aggressive for routine daily use, and the full calcium amount is unlikely to be used efficiently at once. The vitamin D3 serving exceeds the adult daily upper intake level, so long-term use is better guided by measured need and clinical advice.

Study evidence
Calcium Supportive 144 studies
Vitamin D Supportive 202 studies
Anti-Aging
Impact
High effect
B Goal FitB Strength of SupportC+ CoverageA- Formula Quality
Vitamin D · 5000 IU

Vitamin D3 and calcium provide foundational bone and muscle support that helps preserve function with age. The formula does not broadly address oxidative stress, mitochondrial health, or connective tissue.

The fat-containing softgel supports D3 absorption, but both D3 and calcium are supplied at high daily amounts. Combining 5,000 IU D3 with 1,200 mg calcium may increase hypercalcemia or kidney-stone risk when total intake is already high.

Study evidence
Vitamin D Supportive 50 studies
Immunity
Impact
High effect
C+ Goal FitB Strength of SupportC- CoverageA- Formula Quality
Vitamin D · 5000 IU

Vitamin D3 at 5,000 IU directly supports immune regulation and is delivered in a fat-containing softgel. The form and amount are clearly disclosed.

The amount is high for routine maintenance without an identified need, and calcium dominates the product’s main purpose. Users with high calcium levels, kidney-stone risk, or certain calcium disorders should avoid unsupervised high-dose calcium and vitamin D use.

Study evidence
Vitamin D Supportive 85 studies
Testosterone Support
Impact
High effect
B Goal FitA Strength of SupportD+ CoverageC- Formula Quality
Vitamin D · 5000 IU

Vitamin D3 at 5,000 IU gives the formula a strong foundational link to endocrine function, especially when vitamin D status is low. Fat in the softgel supports absorption.

The formula remains narrow and is dominated by a large calcium amount that does not directly broaden testosterone support. Long-term use of 5,000 IU D3 with 1,200 mg calcium may raise calcium levels in susceptible users, so blood testing and individualized dosing are important.

Study evidence
Vitamin D Supportive 56 studies
Energy
Impact
Moderate effect
C- Goal FitA- Strength of SupportD- CoverageB- Formula Quality
Vitamin D · 5000 IU

Vitamin D may improve fatigue when deficiency is present, but it is not a dependable general energy enhancer. The fat-containing softgel uses the preferred D3 form and should support absorption.

The daily vitamin D amount is high for unsupervised maintenance, while the substantial calcium amount shifts the formula toward bone support. Long-term use can raise calcium too far in susceptible users, particularly alongside other vitamin D or calcium products.

Study evidence
Vitamin D Supportive 32 studies
Anti-Inflammatory Support
Impact
Moderate effect
C Goal FitD+ Strength of SupportF CoverageC Formula Quality
Vitamin D · 5000 IU

Potent vitamin D3 may support immune regulation when deficiency is present. The product is a calcium formula and lacks direct anti-inflammatory actives.

It is better suited to monitored bone and vitamin D support. Regular use at 5,000 IU warrants attention to total vitamin D intake and blood levels.

Study evidence
Vitamin D Supportive 101 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1.5 Gram(s)
Vitamin D3 (Cholecalciferol)
5000 IU
Calcium (Calcium Carbonate)
1200 mg
Adults 18–50
Report overview
A Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB+ Value

The 5,000 IU D3 dose sits at the upper end of the preferred daily range, and fat in the softgel supports absorption. The raw D3 source and independent quality certification are not disclosed, which limits traceability. Cost efficiency is good for the active amount, though the high dose may exceed some users' maintenance needs.

C+ Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyA+ Value

Calcium carbonate is identified clearly, but the large serving is likely to be absorbed inefficiently. The vitamin D3 amount is 5,000 IU, which exceeds the adult daily upper limit and may be unsuitable for unsupervised long-term use. The serving cost is low, though the high nutrient amounts warrant careful dosing.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  2. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
    Chowdhury R; Kunutsor S; Vitezova A; Oliver-Williams C; Chowdhury S; Kiefte-de-Jong JC; Khan H; Baena CP; Prabhakaran D; Hoshen MB; Feldman BS; Pan A; Johnson L; Crowe F; Hu FB; Franco OH · BMJ (Clinical research ed.) · 2014
    Meta-analysis95 studies pooledGeneral Health forVitamin D
  3. Effects of Vitamin D3 Supplementation on Muscle Strength, Mass, and Physical Performance in Women with Vitamin D Insufficiency: A Randomized Placebo-Controlled Trial.
    Bislev LS; Langagergaard Rødbro L; Rolighed L; Sikjaer T; Rejnmark L · Calcified tissue international · 2019
    Randomized trial81 participantsGeneral Health forVitamin D
  4. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  5. Effect of monthly high-dose vitamin D on bone density in community-dwelling older adults substudy of a randomized controlled trial.
    Reid IR; Horne AM; Mihov B; Gamble GD; Al-Abuwsi F; Singh M; Taylor L; Fenwick S; Camargo CA; Stewart AW; Scragg R · Journal of internal medicine · 2017
    Randomized trial452 participantsBone Health forVitamin D
  6. Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
    Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Cross-sectional study14,705 participantsBone Health forCalcium
  7. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
    Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
    Meta-analysis1,566 participants7 studies pooledBone Health forCalcium
  8. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  9. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  10. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  11. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  12. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  13. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  14. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  15. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  16. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  17. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  18. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  19. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  20. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  21. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  22. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  23. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  24. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  25. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  26. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  27. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  28. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  29. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  30. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  31. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  32. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  33. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  34. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  35. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  36. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  37. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  38. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  39. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  40. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  41. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  42. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  43. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  44. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  45. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D