Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin.
Petyaev IM; Klochkov VA; Chalyk NE; Pristensky DV; Chernyshova MP; Kyle NH; Bashmakov YK · The journal of nutrition, health & aging · 2019
Randomized trial32 participantsflagAnti-Aging forscienceAstaxanthin
- The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.
Phetcharat L; Wongsuphasawat K; Winther K · Clinical interventions in aging · 2016
Randomized trial34 participantsflagSkin Health flagAnti-Aging forscienceAstaxanthin
- Effectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials.
Yang Q; Li H; Zhang H; Ma L; Zhang X; Wu J · Frontiers in medicine · 2025
Meta-analysis40 studies pooledflagSkin Health forscienceAstaxanthin
- Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing.
Zhou X; Cao Q; Orfila C; Zhao J; Zhang L · Nutrients · 2021
Meta-analysis11 studies pooledflagSkin Health flagAnti-Aging forscienceAstaxanthin
- Oral herbal therapies for treating osteoarthritis.
Cameron M; Chrubasik S · The Cochrane database of systematic reviews · 2015
Meta-analysis5,980 participants49 studies pooledflagJoint Health forscienceBoswellia
- Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
Dalmonte T; Andreani G; Rudelli C; Isani G · Phytotherapy research : PTR · 2024
Meta-analysis1,185 participants13 studies pooledflagJoint Health forscienceBoswellia
- Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial.
Grigorian A; Tabatabaeyan A; Salesi M; Feizi A; Ahmadi AR; Kafeshani M · Food & function · 2025
Randomized trial60 participantsflagJoint Health forscienceAstaxanthin
- Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study.
Jayaram M; Kim J; Baek KS; Jung H; Kim J; M K P; T S C; H B S; Ramaiah V; S P · Journal of medicinal food · 2025
Randomized trial150 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn's disease: good safety profile but lack of efficacy.
Holtmeier W; Zeuzem S; Preiss J; Kruis W; Böhm S; Maaser C; Raedler A; Schmidt C; Schnitker J; Schwarz J; Zeitz M; Caspary W · Inflammatory bowel diseases · 2011
Randomized trial108 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee.
Kulkarni PD; Damle ND; Singh S; Yadav KS; Ghante MR; Bhaskar VH; Hingorani L; Gota VS · Drug metabolism and personalized therapy · 2021
Randomized trialflagAnti-Inflammatory Support forscienceBoswellia
- Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential.
Kidd P · Alternative medicine review : a journal of clinical therapeutic · 2012
Narrative reviewflagAnti-Aging flagVision Support forscienceAstaxanthin
- The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial.
Youssef FM; Ateyya H; Hanna Samy AE; Elmokadem EM · Frontiers in pharmacology · 2025
Randomized trial80 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- The Role of Astaxanthin as an Antioxidant and Anti-Inflammatory Agent in Human Health: A Systematic Review.
Malcangi G; Inchingolo AM; Casamassima L; Trilli I; Ferrante L; Longo M; Inchingolo F; Marinelli G; Palermo A; Dipalma G; Inchingolo AD · International journal of molecular sciences · 2026
Systematic review15 studies pooledflagAnti-Inflammatory Support forscienceAstaxanthin
- Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial.
Rostami S; Alyasin A; Saedi M; Nekoonam S; Khodarahmian M; Moeini A; Amidi F · Frontiers in endocrinology · 2023
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Astaxanthin Modulates Inflammation in Type 2 Diabetes via Regulation of microRNAs, Lysophosphatidylcholine, and α-Hydroxybutyrate.
Sharifi-Rigi A; Zal F; Aarabi MH; Dehghani M; Roustaei Rad N; Taghiyar S · International journal of endocrinology · 2025
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes.
Basereh A; Khoramipour K; Hosseini N; HajHosseini M; Khodabakhshi A; Amirkhosravi L; Khoramipour K · Scientific reports · 2025
Randomized trial90 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee.
Majeed M; Majeed S; Narayanan NK; Nagabhushanam K · Phytotherapy research : PTR · 2019
Randomized trial48 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease.
Karima S; Aghamollaii V; Mahmoodi Baram S; Balenci L; Lanctôt KL; Kiss A; Tafakhori A; Mahdavi M; Rajaei S; Shateri S; Yarhoseini A; Mokhtari F; Fotouhi A; Riazi A · Journal of Alzheimer's disease : JAD · 2023
Randomized trial85 participantsflagAnti-Inflammatory Support forscienceBoswellia
- A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.
Kumar B; Ghaytidak AB; Pandey AK; Somepalli RR; Sarda P; Raychaudhuri SP; Rokkam MP · Journal of the American Nutrition Association · 2025
Randomized trial80 participantsflagAnti-Inflammatory Support flagJoint Health forscienceBoswellia
- A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.
Majeed A; Majeed S; Satish G; Manjunatha R; Rabbani SN; Patil NVP; Mundkur L · Frontiers in pharmacology · 2024
Randomized trial105 participantsflagAnti-Inflammatory Support flagJoint Health forscienceBoswellia
- Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia.
Ciaraldi TP; Boeder SC; Mudaliar SR; Giovannetti ER; Henry RR; Pettus JH · Diabetes, obesity & metabolism · 2023
Randomized trial34 participantsflagCardiovascular Support forscienceAstaxanthin
- Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Wan S; Wu W; Zhang Y; He J; Wang X; An P; Luo J; Zhu Y; Luo Y · Nutrients · 2024
Meta-analysisflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia.
Yoshida H; Yanai H; Ito K; Tomono Y; Koikeda T; Tsukahara H; Tada N · Atherosclerosis · 2010
Randomized trial61 participantsflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- Effects of Astaxanthin Supplementation on Glycemic Control and Lipid Profile in Patients With Prediabetes and Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.
Molani-Gol R; Bohlouli Sardroudi S; Rafraf M · Nutrition and metabolic insights · 2026
Meta-analysis403 participants9 studies pooledflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity.
Saeidi A; Nouri-Habashi A; Razi O; Ataeinosrat A; Rahmani H; Mollabashi SS; Bagherzadeh-Rahmani B; Aghdam SM; Khalajzadeh L; Al Kiyumi MH; Hackney AC; Laher I; Heinrich KM; Zouhal H · Nutrients · 2023
Randomized trial68 participantsflagCardiovascular Support forscienceAstaxanthin
- Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study.
Katagiri M; Satoh A; Tsuji S; Shirasawa T · Journal of clinical biochemistry and nutrition · 2012
Randomized trial96 participantsflagCognitive Support forscienceAstaxanthin
- Effect of astaxanthin-rich extract derived from Paracoccus carotinifaciens on cognitive function in middle-aged and older individuals.
Hayashi M; Ishibashi T; Maoka T · Journal of clinical biochemistry and nutrition · 2020
Clinical trial54 participantsflagCognitive Support forscienceAstaxanthin
- The Effects of Astaxanthin on Cognitive Function and Neurodegeneration in Humans: A Critical Review.
Queen CJJ; Sparks SA; Marchant DC; McNaughton LR · Nutrients · 2024
Narrative reviewflagCognitive Support forscienceAstaxanthin
- Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials.
Liu C; Dong X; Jia J; Ha M · Biological research for nursing · 2024
Meta-analysis346 participants11 studies pooledflagCognitive Support forscienceAstaxanthin
- Astaxanthin and improvement of dementia: A systematic review of current clinical trials.
Utomo NP; Pinzon RT; Latumahina PK; Damayanti KRS · Cerebral circulation - cognition and behavior · 2024
Systematic reviewflagCognitive Support forscienceAstaxanthin
- Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial.
Mohammadi SG; Shafie D; Feizi A; Bagherniya M; Ahmadi AR; Kafeshani M · BMC cardiovascular disorders · 2025
Randomized trial80 participantsflagHeart Health forscienceAstaxanthin
- Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Leung LY; Chan SM; Tam HL; Wong ES · Nutrients · 2022
Meta-analysis321 participants7 studies pooledflagHeart Health forscienceAstaxanthin
- A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.
Hill WS; Dohnalek MH; Ha Y; Kim SJ; Jung JC; Kang SB · Nutrients · 2023
Randomized trial100 participantsflagJoint Health forscienceAstaxanthin
- Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study.
Haroyan A; Mukuchyan V; Mkrtchyan N; Minasyan N; Gasparyan S; Sargsyan A; Narimanyan M; Hovhannisyan A · BMC complementary and alternative medicine · 2018
Randomized trial201 participantsflagJoint Health forscienceBoswellia
- A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.
Sengupta K; Alluri KV; Satish AR; Mishra S; Golakoti T; Sarma KV; Dey D; Raychaudhuri SP · Arthritis research & therapy · 2009
Randomized trial75 participantsflagJoint Health forscienceBoswellia
- The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial.
Ito N; Seki S; Ueda F · Nutrients · 2018
Randomized trial23 participantsflagSkin Health forscienceAstaxanthin
- Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo.
Yoon HS; Cho HH; Cho S; Lee SR; Shin MH; Chung JH · Journal of medicinal food · 2015
Randomized trial44 participantsflagSkin Health forscienceAstaxanthin
- Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers.
Chalyk NE; Klochkov VA; Bandaletova TY; Kyle NH; Petyaev IM · Nutrition research (New York, N.Y.) · 2018
Single-arm trial31 participantsflagSkin Health forscienceAstaxanthin
- Cosmetic benefits of astaxanthin on humans subjects.
Tominaga K; Hongo N; Karato M; Yamashita E · Acta biochimica Polonica · 2012
Other66 participantsflagSkin Health forscienceAstaxanthin
- Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease.
Tian L; Wen Y; Li S; Zhang P; Wang Y; Wang J; Cao K; Du L; Wang N; Jie Y · Frontiers in nutrition · 2022
Single-arm trial60 participantsflagVision Support forscienceAstaxanthin
- Astaxanthin (AstaReal®) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial.
Hecht KA; Marwah M; Wood V; Nishida Y; Bach AE; Gerson J; Hom MM; Schnackenberg J; Raote S; Srivastava S; Negi P; Caston E · Advances in therapy · 2025
Randomized trial64 participantsflagVision Support forscienceAstaxanthin
- Effects of diet containing astaxanthin on visual function in healthy individuals: a randomized, double-blind, placebo-controlled, parallel study.
Sekikawa T; Kizawa Y; Li Y; Miura N · Journal of clinical biochemistry and nutrition · 2023
Randomized trial60 participantsflagVision Support forscienceAstaxanthin
- Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
Martinez-Perez C; Oliveira AP · Nutrients · 2026
Systematic review9 studies pooledflagVision Support forscienceAstaxanthin