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Biotin

Jarrow Formulas
4.7
★ ★ ★ ★ ★
(3377 ratings)
Biotin 5000 mcg
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Score80
A strong active-form biotin capsule for targeted use, with limited breadth and a meaningful blood-test interaction.
How scoring works
Quantity:100 Veggie Cap(s) • (100 servings)
Goals:
Nail Health
Hair Health
Skin Health

Score 80

A strong active-form biotin capsule for targeted use, with limited breadth and a meaningful blood-test interaction.
How scoring works
$9.50($0.09 per serving)
iHerb
$ 15.59
Vitacost
$ 15.59
Daily Vita
$ 12.99
Pure Formulas
$ 11.99
Daily Vita
$ 9.50
Amazon
$ 11.99
Daily Vita
$ 11.99
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Analysis

The capsule explicitly provides d-biotin at a concentrated amount, which is a clear form-quality advantage. It aligns most directly with brittle-nail support and correction of inadequate biotin intake.

High-dose biotin is not a broad hair or skin intervention for well-nourished users. The formula lacks protein, zinc, iron, vitamin D, collagen, silicon, and hydration support, while the calcium carrier adds little goal-specific value.

The long supply and single-active focus make it easy to use and evaluate. Laboratory-test interference remains the most important practical consideration.

Who is it for
  • Adults seeking d-biotin
  • People with brittle nails
  • Users addressing a biotin shortfall
Best for
  • Active-form biotin supplementation
  • Nail keratin support
  • Deficiency-related hair support

Pros

  • Uses d-biotin
  • Clearly states the dose
  • Focused formula
  • Long supply

Cons

  • Does not address other beauty pathways
  • Calcium adds little practical value
  • Dose is far above normal needs
  • Hair and skin benefits are uncertain without deficiency

Warnings

  • The 5,000 mcg biotin amount can interfere with thyroid, hormone, cardiac troponin, and other laboratory tests; disclose use before blood work.

Nutrient quality

79 High impact

The focused biotin formula provides a clearly substantial amount for targeted use. D-biotin is identified, and the concentrated dose is higher than ordinary nutritional needs.

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Ingredient transparency

85 Highest impact

Active amounts are fully disclosed without a hidden blend. D-biotin is specifically named, and the supplied information omits full directions and inactive ingredients.

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Customer satisfaction

68 High impact

The supplied average is strong and rests on a substantial review count. No review text was provided to check recurring complaints or product-specific experiences.

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Value for money

87 Highest impact

Serving efficiency is favorable relative to the disclosed formula. Gummy carbohydrate or low-value additions reduce value compared with cleaner alternatives.

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Report analysis

Goals

Nail Health
Nail Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Biotin · 5000 mcg

Biotin directly supports keratin production, and the disclosed amount sits in a high-potency range commonly used for nail support. The simple capsule or softgel keeps the formula focused and easy to assess.

The product offers strong depth for one pathway but does not supply collagen, silicon, zinc, or amino acids. High-dose biotin can distort thyroid and cardiac troponin laboratory results, so the testing clinician should be told before blood work.

Study evidence
Biotin Supportive 8 studies
Hair Health
Hair Health
Impact
High effect
D+ Goal FitA Strength of SupportD- CoverageB+ Formula Quality
Biotin · 5000 mcg

Five thousand micrograms of biotin may support hair quality when low biotin status is present. Evidence for added hair growth in people without deficiency is limited.

D-biotin is the biologically active form and the 5,000 mcg amount is fully disclosed. High-dose biotin can interfere with thyroid, troponin, and other laboratory tests, so it should be disclosed before blood work.

Study evidence
Biotin Supportive 4 studies
Skin Health
Skin Health
Impact
Moderate effect
F Goal FitC+ Strength of SupportF CoverageB+ Formula Quality

Biotin supports normal skin function when deficiency is present. Human evidence does not show meaningful skin improvement from high-dose biotin in people with adequate intake.

The active D-biotin form and amount are clearly disclosed, but the very high serving does not add a proven skin advantage. High-dose biotin can interfere with some thyroid and cardiac blood tests, so the testing clinician should be told before laboratory work.

Study evidence
Biotin Supportive 10 studies

Ingredients

IngredientAmount per serving
Biotin (D-Biotin)
 5000 mcg
Calcium (Dicalcium Phosphate)
 145 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Biotin (D-Biotin) · 5000 mcg OverallScore100
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The active d-biotin form and targeted dose align closely with common hair and nail support use. A vegetable capsule provides a clean delivery format, and the exact biotin amount is easy to verify. High-dose biotin can interfere with some laboratory tests, including thyroid and cardiac marker testing, so users should tell the testing clinician before blood work.

View ingredientView products
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84 Performance

Biotin 5000 mcg

Spring Valley
<p>The high biotin amount uses the active d-biotin isomer and provides focused support mainly when biotin intake is inadequate. Compared with the original, the clearly stated dose and focused formula improve assessment, but concentrated biotin is most relevant when intake is inadequate and can distort thyroid, hormone, or cardiac tests.</p>
84 Performance

High Potency Biotin 5 mg

Country Life
<p>A specific active form and 5,000 mcg d-biotin support confident assessment of the core formula. Compared with the original, the clearly stated dose and focused formula improve assessment, but concentrated biotin is most relevant when intake is inadequate and can distort thyroid, hormone, or cardiac tests.</p>
89 Performance

Biotin 10000 mcg

California Gold Nutrition
<p>Explicit d-biotin labeling, a very high amount, and a simple softgel provide excellent form quality and cost efficiency for focused hair and nail supplementation. Compared with the original, the clearly stated dose and focused formula improve assessment, but concentrated biotin is most relevant when intake is inadequate and can distort thyroid, hormone, or cardiac tests.</p>
84 Budget

Biotin 5000 mcg

Spring Valley
<p>The high biotin amount uses the active d-biotin isomer and provides focused support mainly when biotin intake is inadequate. Compared with the original, the simpler formula offers lower or closely comparable serving cost, though biotin at supplemental amounts should be disclosed before blood work because it can distort laboratory results.</p>
83 Budget

Biotin 5000 mcg

Doctor's Best
<p>5,000 mcg biotin provides a clearly quantified core formula, though the active is plainly named but its d-biotin isomer is not confirmed. Compared with the original, the simpler formula offers lower or closely comparable serving cost, though biotin at supplemental amounts should be disclosed before blood work because it can distort laboratory results.</p>
81 Budget

Biotin 5000 mcg

Nature's Bounty
<p>D-biotin provides a clear active form in a simple formula. Compared with the original, the simpler formula offers lower or closely comparable serving cost, though biotin at supplemental amounts should be disclosed before blood work because it can distort laboratory results.</p>
83 Value

Biotin 5000 mcg

Lake Avenue Nutrition
<p>The clearly disclosed high biotin amount fits focused hair and nail supplementation, but the label does not confirm the active d-biotin isomer. Clear dosing, a streamlined formula, and favorable serving economics make it a stronger value than the original, although concentrated biotin does not assure hair, skin, or nail benefits without low biotin status.</p>
83 Value

Biotin 5000 mcg

Carlson
<p>5,000 mcg biotin provides a clearly quantified core formula, though the active is plainly named but its d-biotin isomer is not confirmed. Clear dosing, a streamlined formula, and favorable serving economics make it a stronger value than the original, although concentrated biotin does not assure hair, skin, or nail benefits without low biotin status.</p>
84 Value

Quick Dissolve Biotin 5000 mcg Natural Strawberry Flavor

Nature's Bounty
<p>The high biotin amount uses the active d-biotin isomer and provides focused support mainly when biotin intake is inadequate. Clear dosing, a streamlined formula, and favorable serving economics make it a stronger value than the original, although concentrated biotin does not assure hair, skin, or nail benefits without low biotin status.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsSkin Health Hair Health Nail Health forBiotin
  2. Anti-pollution cosmetic-based one-step formation of w/o/w multiple emulsion containing D-biotin for skin protection: fabrication and in vitro and in vivo evaluation.
    Ali A; Iqbal S; Ilyas A; Khan H; Asad MHHB; Fatima N; Akhtar N · Drug delivery and translational research · 2020
    Non-randomized trial15 participantsSkin Health forBiotin
  3. Interventions for infantile seborrhoeic dermatitis (including cradle cap).
    Victoire A; Magin P; Coughlan J; van Driel ML · The Cochrane database of systematic reviews · 2019
    Systematic review35 participants2 studies pooledSkin Health forBiotin
  4. Final report on the safety assessment of biotin.
    Fiume MZ; Cosmetic Ingredient Review Expert Panel · International journal of toxicology · 2002
    Narrative reviewSkin Health forBiotin
  5. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  6. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  7. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health Skin Health forBiotin
  8. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  9. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  10. Brittle nails: response to daily biotin supplementation.
    Hochman LG; Scher RK; Meyerson MS · Cutis · 1993
    Case series35 participantsNail Health forBiotin
  11. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forBiotin
  12. Brittle nails.
    Iorizzo M; Pazzaglia M; M Piraccini B; Tullo S; Tosti A · Journal of cosmetic dermatology · 2009
    Narrative reviewNail Health forBiotin
  13. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  14. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin
  15. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  16. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  17. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin