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Calcium with Vitamin D3

AN Amazing Nutrition Amazing Formulas
4.4
★ ★ ★ ★ ★
(983 ratings)
Vitamin D 1000 IU
Calcium 1200 mg
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Score78
High calcium and useful vitamin D3 make this an economical, focused bone formula. The carbonate form and 1,200 mg calcium serving require more care than a moderate-dose citrate product.
How scoring works
Quantity:220 Softgel(s) • (110 servings)
Goals:
Bone Health
General Health
Immunity
Energy

Score 78

High calcium and useful vitamin D3 make this an economical, focused bone formula. The carbonate form and 1,200 mg calcium serving require more care than a moderate-dose citrate product.
How scoring works
$14.99($0.13 per serving)
iHerb
$ 14.99
Amazon
$ 19.99
Walmart
$ 19.99
Vitacost
$ 30.65
Pure Formulas
$ 17.06
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Analysis

The two-softgel serving provides 1,200 mg of calcium with 1,000 IU of vitamin D3. That combination is directly relevant to bone support, while the oil-containing softgel format may suit vitamin D absorption.

Calcium is supplied as carbonate, which is best taken with food and is less flexible than citrate for some users. The large amount may cover most or all of a person’s daily calcium target before food is counted.

A long supply and low serving cost are practical strengths. The formula does not directly support the many unrelated goals attached to it, and users need to account for dietary calcium before choosing such a concentrated serving.

Who is it for
  • Adults with a confirmed need for substantial calcium support
  • Users who prefer softgels
  • People able to account for calcium from food
Best for
  • Concentrated calcium and vitamin D3
  • Focused bone support
  • Low serving cost

Pros

  • Provides 1,200 mg of calcium
  • Includes 1,000 IU of vitamin D3
  • Uses a softgel with dietary fat
  • Offers a long, economical supply

Cons

  • Uses calcium carbonate rather than citrate
  • The calcium amount is large for one serving
  • The active profile is narrow
  • The broad goal list overstates the formula’s reach

Warnings

  • The 1,200 mg calcium serving may be excessive when dietary calcium is already high and may increase constipation or kidney-stone concerns in susceptible users.
  • Calcium carbonate should be taken with food unless the label directs otherwise, because stomach acid helps its absorption.
  • Calcium can reduce absorption of levothyroxine, iron, and certain antibiotics; follow the medicine-specific spacing interval.

Nutrient quality

81 Highest impact

Substantial calcium and vitamin D3 closely fit bone support. The carbonate form and a high calcium serving reduce flexibility and absorption quality.

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Ingredient transparency

73 High impact

The core active amounts and forms are mostly clear without a proprietary blend. Duplicate naming, missing inactive ingredients, and incomplete directions create some uncertainty.

.

Customer satisfaction

65 High impact

The supplied average rating is positive but not exceptional. The large review count makes the rating relatively reliable.

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Value for money

93 Highest impact

Substantial core doses at a low serving cost provide strong value. The basic calcium form is the main quality trade-off.

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Report analysis

Goals

Bone Health
Impact
Highest effect
A+ Goal FitB Strength of SupportB CoverageA+ Formula Quality
Calcium · 1200 mgVitamin D · 1000 IU

Calcium and vitamin D3 directly support bone mineral supply and calcium absorption. The 1,200 mg calcium serving is large, while the vitamin D3 amount is useful for maintaining absorption support.

Calcium carbonate is a basic form that is best absorbed with food, and the formula lacks vitamin K or magnesium. Taking the full calcium amount at once may reduce absorption efficiency and can increase constipation for some users.

Study evidence
Calcium Supportive 144 studies
Vitamin D Supportive 202 studies
General Health
Impact
Highest effect
A Goal FitB Strength of SupportB- CoverageA- Formula Quality
Vitamin D · 1000 IU

Calcium and vitamin D3 form a logical pairing for calcium absorption and normal skeletal maintenance. The softgel supplies a clearly disclosed vitamin D3 amount along with a substantial calcium serving.

Calcium carbonate is less flexible than citrate because it is best absorbed with food, and the 1200 mg supplemental amount may be unnecessary when dietary calcium is already adequate. That large calcium dose may cause constipation and deserves caution for people with hypercalcemia or a history of calcium-based kidney stones.

Study evidence
Vitamin D Supportive 115 studies
Immunity
Impact
High effect
A- Goal FitC Strength of SupportC CoverageB+ Formula Quality
Vitamin D · 1000 IU

Calcium and vitamin D3 form a logical foundation for calcium absorption and bone maintenance. The disclosed calcium amount is substantial and the fat-containing chewable format may aid vitamin D absorption.

Calcium carbonate is less flexible than citrate and can cause digestive discomfort for some users. Vitamin D appears twice at the same amount, making the intended total unclear, while the high calcium load may be unnecessary when dietary intake is already adequate.

Study evidence
Vitamin D Supportive 85 studies
Energy
Impact
High effect
C+ Goal FitB- Strength of SupportD CoverageB+ Formula Quality
Vitamin D · 1000 IU

Vitamin D3 may support fatigue related to low vitamin D status, but the formula is primarily designed for calcium and bone support. Calcium carbonate does not directly provide a strong energy mechanism.

The softgel format can aid fat-soluble vitamin delivery, while duplicate vitamin D entries make the disclosure less clean. Energy coverage is narrow and depends mainly on correcting a vitamin D gap.

Study evidence
Vitamin D Supportive 32 studies
Anti-Inflammatory Support
Impact
Moderate effect
C Goal FitB- Strength of SupportD- CoverageC+ Formula Quality
Vitamin D · 1000 IU

Vitamin D3 may support balanced immune signaling when vitamin D status is low. The 1,000 IU amount is a maintenance dose and is unlikely to provide broad anti-inflammatory effects by itself.

Softgel delivery suits fat-soluble vitamin D3, but the formula is dominated by 1,200 mg of calcium for bone health. Calcium does not add a distinct anti-inflammatory pathway and may be unnecessary for someone seeking vitamin D alone.

Study evidence
Vitamin D Supportive 101 studies
Anti-Aging
Impact
Moderate effect
C- Goal FitC- Strength of SupportC- CoverageB- Formula Quality
Vitamin D · 1000 IU

Vitamin D3 and calcium support skeletal maintenance, which is relevant to healthy aging. Calcium carbonate is less absorbable than preferred forms, and the formula lacks vitamin K2 for coordinated calcium handling.

The amounts are clearly disclosed, but the high calcium serving may be unnecessary for people with adequate dietary intake. The product is structurally focused and does not address mitochondrial, glycation, inflammatory, or neurological aging.

Study evidence
Vitamin D Supportive 50 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Vitamin D (Cholecalciferol, Vitamin D3)
1000 IU
Calcium (Calcium Carbonate)
1200 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
A Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

A lipid-based softgel pairs a maintenance amount of D3 with a substantial calcium dose. The delivery format supports absorption, but the raw D3 source and independent testing are not disclosed. It may suit combined calcium and vitamin D needs, though vitamin D value alone is weak.

C+ Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyA+ Value

Calcium carbonate provides a basic, less readily absorbed source, though the mineral amount is clearly stated. The large single serving may be absorbed less efficiently than divided intake. A very low serving cost and simple ingredient profile are the main advantages.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  2. Effects of vitamin D and high dairy protein intake on bone mineralization and linear growth in 6- to 8-year-old children: the D-pro randomized trial.
    Stounbjerg NG; Thams L; Hansen M; Larnkjær A; Clerico JW; Cashman KD; Mølgaard C; Damsgaard CT · The American journal of clinical nutrition · 2022
    Randomized trial200 participantsBone Health forVitamin D
  3. Vitamin D and HRT: no benefit additional to that of HRT alone in prevention of bone loss in early postmenopausal women. A 2.5-year randomized placebo-controlled study.
    Komulainen M; Tuppurainen MT; Kröger H; Heikkinen AM; Puntila E; Alhava E; Honkanen R; Saarikoski S · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1997
    Randomized trial464 participantsBone Health forVitamin D
  4. Impact of serum 25-hydroxyvitamin D levels on fragility fractures in patients undergoing chronic hemodialysis.
    Hori M; Takahashi H; Kondo C; Tokoroyama S; Kanda A; Furuhashi K; Mori Y; Shirasawa Y; Takeda A; Morozumi K; Maruyama S · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Cohort study292 participantsBone Health forVitamin D
  5. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  6. Calcium supplementation provides an extended window of opportunity for bone mass accretion after menarche.
    Rozen GS; Rennert G; Dodiuk-Gad RP; Rennert HS; Ish-Shalom N; Diab G; Raz B; Ish-Shalom S · The American journal of clinical nutrition · 2003
    Randomized trial100 participantsBone Health forCalcium
  7. Calcium supplementation and bone mineral density in postmenopausal women using estrogen replacement therapy.
    Haines CJ; Chung TK; Leung PC; Hsu SY; Leung DH · Bone · 1995
    Randomized trialBone Health forCalcium
  8. Relationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression.
    Rabenda V; Bruyère O; Reginster JY · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
    Meta-analysis47,365 participants15 studies pooledBone Health forCalcium
  9. Bone turnover and the response to alendronate treatment in postmenopausal osteoporosis.
    Gonnelli S; Cepollaro C; Pondrelli C; Martini S; Montagnani A; Monaco R; Gennari C · Calcified tissue international · 1999
    Randomized trial100 participantsBone Health forCalcium
  10. Calcium and osteoporosis.
    Nordin BE · Nutrition (Burbank, Los Angeles County, Calif.) · 1998
    Meta-analysis20 studies pooledBone Health forCalcium
  11. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  12. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  13. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  14. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  15. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  16. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  17. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  18. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  19. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  20. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  21. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  22. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  23. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  24. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  25. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  26. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  27. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  28. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  29. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  30. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  31. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  32. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  33. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  34. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  35. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  36. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  37. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  38. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  39. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  40. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  41. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  42. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  43. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D