Mega Benfotiamine 250 mg
Life Extension
Mega Benfotiamine 250 mg
4.7
★ ★ ★ ★ ★
(5260 ratings)
Thiamin 10 mg
Score 92.0
A high-potency, bioavailable B1 product from a trusted brand, excellent for intensive nerve and metabolic support.
Quantity: 120 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (120 servings)
Selected goals:
Other goals:
Energy
Brain Health
Cognitive Support
Cardiovascular Support
Testosterone Support
leaderboard Score 92.0
A high-potency, bioavailable B1 product from a trusted brand, excellent for intensive nerve and metabolic support.
insights Analysis
This Life Extension Mega Benfotiamine product offers a substantial 250mg dose of benfotiamine, a highly bioavailable, fat-soluble form of Vitamin B1. This increased potency is particularly beneficial for individuals seeking stronger support for nerve health, glucose metabolism, and addressing thiamine deficiencies, as benfotiamine is better absorbed and retained in the body than conventional thiamine. Its higher dosage makes it more suitable for targeted therapeutic applications recommended by many nutritionists for conditions like diabetic neuropathy.
- High 250mg dose of Benfotiamine, suitable for therapeutic use.
- Uses Benfotiamine, a superior bioavailable form of B1.
- From Life Extension, a reputable brand.
- Good review count.
- 120 servings provide a long-lasting supply.
- Higher price per serving compared to some alternatives, though justified by the higher dose and form.
$22.50($0.18 per serving)
 Pure Formulas | $ 22.50 | |
 iHerb | $ 22.50 | |
 Vitacost | $ 22.50 |
bolt Effectiveness for goals
Thiamin, also known as Vitamin B1, is crucial for converting carbohydrates into energy and plays a vital role in metabolism. It supports the healthy function of the nervous system, muscles, and heart. Maintaining adequate thiamin levels is essential for overall cellular function.
Yes, thiamin supplements are highly effective in treating and preventing thiamin deficiency. Deficiency can result from inadequate dietary intake, excessive alcohol consumption, or certain medical conditions. Supplementation helps to restore normal thiamin levels and alleviate associated symptoms.
High-dose thiamin administration is a critical and effective treatment for Wernicke-Korsakoff syndrome (WKS), a severe neurological disorder often associated with chronic alcohol abuse and thiamin deficiency. Early and aggressive supplementation can prevent the progression of Wernicke's encephalopathy and may improve outcomes for Korsakoff's psychosis. It is often administered intravenously in clinical settings.
Thiamin supplementation is the primary and highly effective treatment for beriberi, a disease caused by severe thiamin deficiency. It can reverse the various symptoms affecting the cardiovascular system (wet beriberi) and the nervous system (dry beriberi). Prompt treatment is crucial for recovery.
Some research suggests that certain forms of thiamin, such as benfotiamine, may be effective in managing symptoms of diabetic neuropathy. It is thought to work by influencing metabolic pathways and reducing oxidative stress, which contribute to nerve damage in individuals with diabetes. However, more large-scale clinical trials are needed to confirm these findings.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for thiamin is 1.2 mg per day for adult men and 1.1 mg per day for adult women. These amounts are generally sufficient to prevent deficiency in healthy individuals. Higher dosages may be used under professional guidance for specific conditions.
Yes, Thiamin supplements can generally be taken with or without food. Taking it with food may help some individuals avoid mild stomach upset. Consistent intake, rather than meal timing, is often more critical for absorption.
No Upper Tolerable Intake Level (UL) has been established for Thiamin due to a lack of evidence of adverse effects from high intakes. Even at very high doses, Thiamin is generally considered safe because it is water-soluble and any excess is typically excreted in urine. However, extremely high doses should only be used under professional supervision.
There is no specific "best" time of day to take Thiamin, as its absorption is not significantly affected by morning or evening intake. Some individuals prefer to take B vitamins in the morning to align with the body's natural energy cycles. Consistency in taking the supplement at the same time each day is often more beneficial.
Yes, Thiamin supplements are commonly available as thiamin hydrochloride and thiamin mononitrate, which are synthetic forms readily absorbed. Benfotiamine and sulbutiamine are also available, which are lipid-soluble derivatives sometimes used for specific purposes due to their enhanced bioavailability. The choice of form may depend on individual needs and professional recommendations.
health_and_safety Safety & interactions
Chronic alcohol consumption can significantly impair Thiamin absorption and utilization, leading to a deficiency. Alcohol also increases the body's Thiamin requirements and its excretion. This interaction is a major cause of Thiamin deficiency in individuals with alcohol use disorder.
Conditions such as chronic alcoholism, bariatric surgery, certain malabsorption syndromes, and persistent vomiting can lead to Thiamin deficiency. While Thiamin supplementation is often critical in these cases, individuals with specific liver or kidney conditions should discuss supplement use with their healthcare provider. This ensures appropriate dosage and monitoring for any potential interactions.
Thiamin, or Vitamin B1, is generally considered safe when taken at recommended doses. High doses typically do not cause serious side effects because it is a water-soluble vitamin, and excess is usually excreted by the body. Allergic reactions are rare but can occur, especially with intravenous administration.
Thiamin is a water-soluble vitamin, meaning the body excretes excess amounts in urine. Consequently, there is no established Upper Limit (UL) for Thiamin, as no toxicity has been reported from oral intake. However, extremely high doses administered intravenously have rarely been associated with adverse effects.
Thiamin is essential for fetal development and is considered safe for pregnant and breastfeeding individuals at recommended daily allowances. Higher doses might be prescribed by a healthcare provider for specific deficiencies. It is always advisable to discuss any new supplement use with a doctor during these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Thiamine | 10 mg |
Benfotiamine | 250 mg |
Categories
Thiamin 98.0
This product represents one of the most effective ways to deliver thiamine to the body due to its high dose of benfotiamine, which is consistently lauded for superior absorption and efficacy over other thiamine forms.
Goals
Energy 95.0
The potent 250mg dose of highly absorbed benfotiamine ensures maximum support for carbohydrate metabolism, directly fueling cellular energy production more effectively than lower doses or less bioavailable forms.
Brain Health 95.0
With a substantial benfotiamine dose, this product provides enhanced support for crossing the blood-brain barrier, protecting neurons, and optimizing neurotransmitter function, crucial for robust brain health.
Cognitive Support 95.0
The higher concentration of bioavailable B1 means more effective support for cognitive processes, including memory, focus, and overall mental sharpness, addressing potential deficiencies more comprehensively.
Recommended Alternatives
95 Value 
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
Offers a remarkably high 600mg dose of Benfotiamine for 27 cents per serving, which provides an exceptionally high amount of active ingredient per dollar compared to the original, making it a superior value for intensive thiamine support.
78 Value 
Vitamin B1 500 mg
Vitamatic
4.8
★★★★★
(291 ratings)
While using a less bioavailable form, this product offers an extremely high 500mg dose of thiamine at a much lower price per serving (11 cents), providing a far greater quantity of B1 per dollar, representing excellent value for mass supplementation.
80 Value 
Super Potency Vitamin B 1 (Thiamin) 500 mg
Solgar
4.6
★★★★★
(4557 ratings)
Offers a very high 500mg dose of standard thiamine from a premium brand at a competitive price (16 cents), delivering a substantial amount of B1 per dollar, representing strong value for high-dose general thiamine needs.
98 Performance
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
Delivers an exceptionally high 600mg of Benfotiamine, making it significantly more potent for specific therapeutic applications requiring very high B1 absorption, surpassing the original's dose for maximal effect.
94 Performance 
Benfotiamine 300 mg
Doctor's Best
4.6
★★★★★
(8890 ratings)
Offers a higher 300mg dose of Benfotiamine, building upon the original product's strength with increased potency for greater efficacy in supporting nerve and metabolic health.
93 Performance 
Benfotiamine 300 mg Maximum Strength
Swanson
4.8
★★★★★
(478 ratings)
Provides a higher 300mg dose of the same highly absorbable Benfotiamine form, offering incremental benefits over the 250mg dose for those seeking maximum B1 support.
75 Budget
Vitamin B1 500 mg
Vitamatic
4.8
★★★★★
(291 ratings)
Offers a very high dose of standard Thiamine Mononitrate at a significantly lower price per serving (11 cents), providing a large quantity of B1 for general support, though less bioavailable than Benfotiamine.
78 Budget
Super Potency Vitamin B 1 (Thiamin) 500 mg
Solgar
4.6
★★★★★
(4557 ratings)
Provides a very high 500mg dose of Thiamine Hydrochloride at a lower price per serving (16 cents), offering substantial thiamine support, but not with the same enhanced absorption as benfotiamine.
65 Budget 
B-1 100 mg
NOW
4.8
★★★★★
(11915 ratings)
While much cheaper per serving (4 cents), this offers only 100mg of standard Thiamine, which is significantly less potent and bioavailable than the original's 250mg Benfotiamine for targeted effects.
95 Value
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
Offers a remarkably high 600mg dose of Benfotiamine for 27 cents per serving, which provides an exceptionally high amount of active ingredient per dollar compared to the original, making it a superior value for intensive thiamine support.
78 Value
Vitamin B1 500 mg
Vitamatic
4.8
★★★★★
(291 ratings)
While using a less bioavailable form, this product offers an extremely high 500mg dose of thiamine at a much lower price per serving (11 cents), providing a far greater quantity of B1 per dollar, representing excellent value for mass supplementation.
80 Value
Super Potency Vitamin B 1 (Thiamin) 500 mg
Solgar
4.6
★★★★★
(4557 ratings)
Offers a very high 500mg dose of standard thiamine from a premium brand at a competitive price (16 cents), delivering a substantial amount of B1 per dollar, representing strong value for high-dose general thiamine needs.
98 Performance
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
Delivers an exceptionally high 600mg of Benfotiamine, making it significantly more potent for specific therapeutic applications requiring very high B1 absorption, surpassing the original's dose for maximal effect.
94 Performance
Benfotiamine 300 mg
Doctor's Best
4.6
★★★★★
(8890 ratings)
Offers a higher 300mg dose of Benfotiamine, building upon the original product's strength with increased potency for greater efficacy in supporting nerve and metabolic health.
93 Performance
Benfotiamine 300 mg Maximum Strength
Swanson
4.8
★★★★★
(478 ratings)
Provides a higher 300mg dose of the same highly absorbable Benfotiamine form, offering incremental benefits over the 250mg dose for those seeking maximum B1 support.