P-5-P/Mag
Terry Naturally
P-5-P/Mag
4.8
★ ★ ★ ★ ★
(2700 ratings)
Vitamin B6 10 mg
Score 78.0
Features the superior P-5-P form of B6, making it highly bioavailable. However, the 10mg dosage is low, and the price per serving is very high.
Quantity: 120 Capsule(s)Servings size: 1 Capsule(s) (120 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
leaderboard Score 78.0
Features the superior P-5-P form of B6, making it highly bioavailable. However, the 10mg dosage is low, and the price per serving is very high.
insights Analysis
This product stands out for using Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of Vitamin B6, which is crucial for maximizing absorption and direct utilization by the body. This is a significant advantage over the common Pyridoxine HCl form, as it bypasses the need for liver conversion. While the 10mg dosage is sufficient for basic daily needs or for individuals sensitive to higher doses, it may not be adequate for those seeking significant therapeutic effects for intense energy, brain health, or mood support. The primary drawback is its very high price per serving, making it an expensive option for the dosage provided.
- Contains Pyridoxal 5-Phosphate (P-5-P), the highly bioavailable and active form of Vitamin B6.
- Bypasses the need for liver conversion, ensuring better utilization, especially for those with genetic variations.
- Well-suited for individuals who may be sensitive to higher doses of B6 HCl or need precise intake.
- Very high price per serving, making it a premium-priced option for the dosage.
- Low 10mg dosage may not be sufficient for individuals with significant deficiencies or therapeutic needs for energy, brain health, or mood support.
- The product name implies Magnesium, but the provided ingredient list only specifies Vitamin B6, which could be misleading.
$22.36($0.18 per serving)
 iHerb | $ 22.36 | |
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bolt Effectiveness for goals
Yes, Vitamin B6 is a widely recognized and often recommended treatment for nausea and vomiting in pregnancy, commonly known as morning sickness. It is considered a first-line pharmacological therapy for mild to moderate symptoms. Pregnant individuals should consult their healthcare provider before taking any supplements.
Vitamin B6, or pyridoxine, is crucial for over 100 enzyme reactions, primarily involved in protein metabolism, red blood cell formation, and nervous system health. It plays a key role in metabolic processes that convert food into energy. Maintaining adequate B6 levels supports overall health and proper bodily functions.
Absolutely, Vitamin B6 is vital for brain development and function, and for maintaining a healthy nervous system. It is involved in the synthesis of several key neurotransmitters, such as serotonin, dopamine, and GABA, which regulate mood, sleep, and cognitive processes. Adequate B6 intake is essential for proper nerve signaling.
Some studies suggest that Vitamin B6 supplementation may help reduce certain PMS symptoms, particularly mood swings, irritability, and breast tenderness. The exact mechanism is not fully understood, but it may involve its role in neurotransmitter synthesis. However, evidence is mixed, and more robust research is needed.
Vitamin B6 is involved in the production of neurotransmitters like serotonin and norepinephrine, which are critical for mood regulation. Some research indicates that B6 supplementation may positively influence mood and reduce symptoms of depression, particularly in individuals with a deficiency. However, it should not replace prescribed treatments for mental health conditions.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men and women (19-50 years) is 1.3 mg per day. For those over 50, it is 1.7 mg for men and 1.5 mg for women. These recommendations are for healthy individuals.
Yes, taking excessively high doses of Vitamin B6, particularly from supplements, can be harmful. The most well-known adverse effect is sensory neuropathy, which can cause numbness and tingling in the extremities. This risk increases with doses significantly above the Tolerable Upper Intake Level (UL) of 100 mg/day.
The Tolerable Upper Intake Level (UL) for Vitamin B6 in adults is 100 mg per day. Consuming amounts significantly above this UL, particularly from supplements, can lead to adverse effects like peripheral neuropathy. It is advisable not to exceed this limit without professional guidance.
There is no specific "best" time to take Vitamin B6; it can be taken at any time of day. Consistency in taking the supplement is generally more important than the exact timing. Some individuals may prefer to take it with a meal to avoid potential stomach upset.
Vitamin B6 supplements commonly contain pyridoxine hydrochloride (pyridoxine HCl). The active coenzyme form, pyridoxal 5'-phosphate (P5P), is also available in some supplements. Other forms like pyridoxal and pyridoxamine also exist in food.
health_and_safety Safety & interactions
Long-term intake of high doses, typically exceeding 200 mg per day, can lead to sensory peripheral neuropathy, characterized by numbness, tingling, and pain in the extremities. Other less common side effects might include skin lesions, photosensitivity, and gastrointestinal issues. These effects usually resolve after discontinuing supplementation.
For adults, the tolerable upper intake level (UL) for Vitamin B6 is set at 100 mg per day from supplements and fortified foods. Consuming amounts above this UL regularly increases the risk of adverse effects, primarily neurological damage. This limit is established to prevent potential harm.
The primary and most concerning symptom of Vitamin B6 toxicity, typically from chronic high doses, is sensory peripheral neuropathy. This involves symptoms like numbness, tingling, and burning pain, often starting in the hands and feet. Other less common signs might include skin lesions or gastrointestinal upset.
Yes, Vitamin B6 can interact with several medications. For instance, it may reduce the effectiveness of levodopa (used for Parkinson's disease) and can interact with anti-seizure medications like phenytoin and phenobarbital. It is important to consult a healthcare provider when combining Vitamin B6 supplements with prescription drugs.
Vitamin B6 is generally considered safe during pregnancy and breastfeeding when taken within recommended dietary allowances. Higher doses might be used under medical supervision for specific conditions like severe morning sickness. Always discuss any supplementation with a healthcare provider to ensure appropriate dosing.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 10 mg |
Magnesium | 100 mg |
Zinc | 5 mg |
Categories
Vitamin B6 80.0
This product is commendable within the Vitamin B6 category for exclusively using the active P-5-P form. However, its high price per serving for a comparatively low 10mg dose lowers its overall category score when considering value for money.
Goals
Brain Health 75.0
P-5-P is the preferred form for neurotransmitter synthesis crucial for brain health. While the form is optimal, the 10mg dose is modest and might not deliver profound effects for those seeking robust brain support.
Mood Support 75.0
For mood support, the P-5-P form is highly effective as it directly participates in serotonin and dopamine production. The 10mg dose can offer foundational support, but higher doses are often used for more pronounced mood benefits.
Energy 70.0
The P-5-P form is excellent for energy metabolism due to its direct bioavailability. However, the 10mg dosage is quite low for significant impact on energy levels for individuals with greater needs, making it more suitable for maintenance.
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