P-5-P/Mag
Terry Naturally
P-5-P/Mag
Vitamin B6 10 mg
Score 90.0
An excellent supplement combining the active form of Vitamin B6 (P-5-P) with highly absorbable Magnesium and Zinc for synergistic health benefits.
Quantity: 60 Capsule(s) • (60 servings)
Goals:
Detoxification
Stress Relief
Score 90.0
An excellent supplement combining the active form of Vitamin B6 (P-5-P) with highly absorbable Magnesium and Zinc for synergistic health benefits.
Analysis
Terry Naturally P-5-P/Mag features 10mg of Pyridoxal 5-Phosphate (P-5-P), the coenzyme form of Vitamin B6, which is immediately bioavailable and bypasses the liver conversion step, minimizing potential toxicity even at higher doses than pyridoxine HCl. It also includes 100mg of Magnesium Glycinate Chelate and 5mg of Zinc Glycinate Chelate, both highly absorbable forms. Magnesium is vital for over 300 enzymatic reactions, including energy production and nerve function, while Zinc is essential for immune health, cell growth, and cognitive function. The synergy between P-5-P and Magnesium is particularly beneficial for neurotransmitter synthesis and nervous system health, contributing powerfully to mood and brain function. This product reflects a strong understanding of nutrient synergy and bioavailability.
Pros
- Contains Pyridoxal 5-Phosphate (P-5-P), the active and most bioavailable form of Vitamin B6.
- Includes highly absorbable chelated forms of Magnesium (Glycinate) and Zinc (Glycinate) for synergistic benefits.
- Well-formulated for broad support of energy, brain health, and mood due to ingredient synergy.
Cons
- Slightly higher price per serving compared to basic B6 supplements, though justified by ingredient quality.
- The dosage of B6 (10mg) might be considered low by those looking for very high therapeutic doses, but it is effective and safe for general support.
$9.10($0.15 per serving)
 Daily Vita | $ 9.10 | |
 Walmart | $ 14.36 | |
 iHerb | $ 14.36 | |
 Vitacost | $ 14.36 | |
| Daily Vita | $ 14.36 |
Effectiveness for goals
Yes, Vitamin B6 is a widely recognized and often recommended treatment for nausea and vomiting in pregnancy, commonly known as morning sickness. It is considered a first-line pharmacological therapy for mild to moderate symptoms. Pregnant individuals should consult their healthcare provider before taking any supplements.
Vitamin B6, or pyridoxine, is crucial for over 100 enzyme reactions, primarily involved in protein metabolism, red blood cell formation, and nervous system health. It plays a key role in metabolic processes that convert food into energy. Maintaining adequate B6 levels supports overall health and proper bodily functions.
Absolutely, Vitamin B6 is vital for brain development and function, and for maintaining a healthy nervous system. It is involved in the synthesis of several key neurotransmitters, such as serotonin, dopamine, and GABA, which regulate mood, sleep, and cognitive processes. Adequate B6 intake is essential for proper nerve signaling.
Some studies suggest that Vitamin B6 supplementation may help reduce certain PMS symptoms, particularly mood swings, irritability, and breast tenderness. The exact mechanism is not fully understood, but it may involve its role in neurotransmitter synthesis. However, evidence is mixed, and more robust research is needed.
Vitamin B6 is involved in the production of neurotransmitters like serotonin and norepinephrine, which are critical for mood regulation. Some research indicates that B6 supplementation may positively influence mood and reduce symptoms of depression, particularly in individuals with a deficiency. However, it should not replace prescribed treatments for mental health conditions.
Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men and women (19-50 years) is 1.3 mg per day. For those over 50, it is 1.7 mg for men and 1.5 mg for women. These recommendations are for healthy individuals.
Yes, taking excessively high doses of Vitamin B6, particularly from supplements, can be harmful. The most well-known adverse effect is sensory neuropathy, which can cause numbness and tingling in the extremities. This risk increases with doses significantly above the Tolerable Upper Intake Level (UL) of 100 mg/day.
The Tolerable Upper Intake Level (UL) for Vitamin B6 in adults is 100 mg per day. Consuming amounts significantly above this UL, particularly from supplements, can lead to adverse effects like peripheral neuropathy. It is advisable not to exceed this limit without professional guidance.
There is no specific "best" time to take Vitamin B6; it can be taken at any time of day. Consistency in taking the supplement is generally more important than the exact timing. Some individuals may prefer to take it with a meal to avoid potential stomach upset.
Vitamin B6 supplements commonly contain pyridoxine hydrochloride (pyridoxine HCl). The active coenzyme form, pyridoxal 5'-phosphate (P5P), is also available in some supplements. Other forms like pyridoxal and pyridoxamine also exist in food.
Safety & interactions
Long-term intake of high doses, typically exceeding 200 mg per day, can lead to sensory peripheral neuropathy, characterized by numbness, tingling, and pain in the extremities. Other less common side effects might include skin lesions, photosensitivity, and gastrointestinal issues. These effects usually resolve after discontinuing supplementation.
For adults, the tolerable upper intake level (UL) for Vitamin B6 is set at 100 mg per day from supplements and fortified foods. Consuming amounts above this UL regularly increases the risk of adverse effects, primarily neurological damage. This limit is established to prevent potential harm.
The primary and most concerning symptom of Vitamin B6 toxicity, typically from chronic high doses, is sensory peripheral neuropathy. This involves symptoms like numbness, tingling, and burning pain, often starting in the hands and feet. Other less common signs might include skin lesions or gastrointestinal upset.
Yes, Vitamin B6 can interact with several medications. For instance, it may reduce the effectiveness of levodopa (used for Parkinson's disease) and can interact with anti-seizure medications like phenytoin and phenobarbital. It is important to consult a healthcare provider when combining Vitamin B6 supplements with prescription drugs.
Vitamin B6 is generally considered safe during pregnancy and breastfeeding when taken within recommended dietary allowances. Higher doses might be used under medical supervision for specific conditions like severe morning sickness. Always discuss any supplementation with a healthcare provider to ensure appropriate dosing.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 10 mg |
Magnesium | 100 mg |
Zinc | 5 mg |
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Children 4+ Vegetarian
Report overviewCategories
Vitamin B6 95.0
This product excels in the Vitamin B6 collection by using the active and highly bioavailable P-5-P form, which is superior to pyridoxine HCl. The inclusion of synergistic minerals like Magnesium and Zinc further enhances its utility, making it a premium choice for those seeking comprehensive B6 support.
Goals
Brain Health 95.0
P-5-P is directly involved in the synthesis of critical neurotransmitters, while Magnesium is essential for nerve transmission and synaptic plasticity. Zinc supports cognitive function and neuronal communication, making this combination exceptionally effective for promoting overall brain health and function.
Mood Support 95.0
Both P-5-P and Magnesium are well-regarded for their roles in mood regulation; P-5-P by facilitating neurotransmitter synthesis, and Magnesium by calming the nervous system and reducing stress. Zinc also plays a part in balancing neurotransmitters, making this product highly effective for mood stability.
Energy 90.0
Magnesium is a cornerstone for ATP (energy) production, and P-5-P is crucial for converting macronutrients into energy. The synergistic action of these ingredients provides robust support for cellular energy pathways, leading to improved vitality and reduced fatigue.
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