Micronized L-Glutamine 500 mg
Natural Factors
Micronized L-Glutamine 500 mg
Glutamine 500 mg
Score 28.0
A micronized 500mg L-Glutamine capsule that offers improved absorption but suffers from a very low dose per serving and a high cost when aiming for clinically relevant daily amounts for its listed goals.
Quantity: 90 Capsule(s) • (90 servings)
Goals:
Digestive Health
Score 28.0
A micronized 500mg L-Glutamine capsule that offers improved absorption but suffers from a very low dose per serving and a high cost when aiming for clinically relevant daily amounts for its listed goals.
Analysis
This Natural Factors L-Glutamine product offers 500 mg per capsule, distinguished by its micronized form which theoretically enhances solubility and absorption, a positive aspect for bioavailability. However, similar to other 500mg formulations, this dose is significantly below the 5-10 gram threshold commonly recommended for substantial benefits in immunity, fitness, muscle gain, or digestive health, as advised by nutritionists. Despite the micronization, the high cost of $0.11 per 500mg serving means achieving an effective daily dose of 5g would cost $1.10, making it one of the most expensive options per therapeutic dose when compared to bulk powder alternatives.
Pros
- Micronized form may improve solubility and potentially enhance absorption compared to standard L-Glutamine
- Convenient capsule form for ease of consumption
Cons
- Very low dose per serving (500mg), requiring many capsules to reach a therapeutic effect
- High cost per effective daily dose (e.g., 5g) compared to bulk powder L-Glutamine products
- Fewer servings per bottle (90) compared to some 100-count alternatives for similar price points
Warnings
- The micronized form improves absorption but does not compensate for the significantly low dosage. Users should be aware of the high cost for a sustained, higher-dose regimen for the intended goals.
$10.47($0.11 per serving)
 iHerb | $ 10.47 |
Effectiveness for goals
Glutamine is a vital fuel source for intestinal cells and plays a key role in maintaining the integrity of the gut barrier. It helps support the health of the intestinal lining, crucial for nutrient absorption and protecting against harmful substances.
L-Glutamine is an amino acid, a building block for proteins, and is the most abundant free amino acid in the human body. It plays a crucial role in immune function, intestinal health, and provides fuel for cells in the gut lining. The body can produce glutamine, but supplemental forms are sometimes used.
Research indicates that glutamine plays a critical role in maintaining intestinal barrier function and reducing gut permeability, especially in conditions involving increased gut stress or injury. While promising, more studies are needed to confirm its widespread effectiveness for "leaky gut" in the general population.
L-Glutamine is a vital nutrient for the cells lining the small intestine, providing a primary energy source for enterocytes. It is believed to help maintain the integrity of the gut lining, potentially reducing intestinal permeability. This makes it a popular supplement for supporting overall digestive health.
Glutamine is often studied for its potential role in replenishing glycogen stores and reducing muscle soreness after intense exercise. Some research suggests it may aid in post-workout recovery, particularly under conditions of heavy training or stress.
Dosage, timing & forms
For muscle recovery, many individuals choose to take Glutamine immediately after a workout. Some also take an additional dose before bed or spread throughout the day. This timing aims to support the body's natural recovery processes.
Typical dosages for L-Glutamine range from 5 to 10 grams per day, often divided into multiple doses. For specific applications like intense athletic recovery or gut health, some individuals may use slightly higher amounts under guidance. It is generally advisable to start with a lower dose and adjust as needed.
Common daily dosages for L-Glutamine supplementation often range from 5 to 20 grams, depending on individual needs and goals. It is frequently split into multiple smaller doses throughout the day. Specific amounts can vary for different applications like exercise recovery or digestive support.
For supporting gut health, dosages for Glutamine can vary, but generally range from 5 to 10 grams per day. This amount is often divided into smaller doses taken a few times daily. Consistent use over time is typically recommended.
For consistent benefits, Glutamine is often taken daily. Depending on the total dosage, it might be split into 2-3 smaller doses throughout the day to maintain elevated levels. This approach is common for supporting muscle recovery, immune function, or gut health.
Safety & interactions
Yes, L-Glutamine is generally considered safe for most healthy adults when taken at recommended dosages. It is a naturally occurring amino acid in the body and in many foods. However, individuals with certain medical conditions should consult a healthcare professional before use.
Glutamine may interact with certain medications, including chemotherapy drugs or anti-seizure medications. It's crucial to consult a healthcare professional before taking glutamine if you are on any prescription drugs. They can advise on potential interactions and safe usage.
At standard dosages, side effects from L-Glutamine are uncommon and usually mild, potentially including digestive upset like nausea, gas, or mild stomach pain. Very high doses could potentially lead to more significant issues. If adverse reactions occur, discontinuing use and consulting a professional is advised.
Glutamine is generally well-tolerated, but some individuals may experience mild side effects such as nausea, stomach upset, or gas. These effects are typically rare and often resolve with dose adjustment or discontinuation. Severe side effects are uncommon with appropriate use.
L-Glutamine is generally not associated with significant interactions with most medications or supplements. However, individuals taking certain medications, particularly those for cancer or liver/kidney conditions, should consult a healthcare provider. There's limited data on specific interactions, so caution is always recommended.
Ingredients
| Ingredient | Amount per serving |
|---|---|
L-Glutamine, Micronized | 500 mg |
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overviewCategories
Glutamine 35.0
As a L-Glutamine supplement, it contributes to the collection, but the very low dosage and high cost per gram for an effective daily intake make it a less desirable option compared to more potent and economical alternatives.
Goals
Immunity 35.0
The micronized form might offer a slight edge in absorption for this small dose, but 500mg is still considerably lower than effective dosages for significant immune system support recommended by experts.
Fitness 30.0
Despite micronization, a 500mg dose is largely insufficient to impact athletic performance, muscle recovery, or reduce post-exercise soreness effectively; higher doses are generally required for noticeable benefits.
Digestive Health 30.0
While beneficial for gut health, 500mg is too small a dose for therapeutic support or repair of the intestinal lining; higher dosages (5g+) are typically required for substantial impact, as supported by online reviews and nutritionist advice.
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