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Curcumin Phytosome

NOW
4.8
★ ★ ★ ★ ★
(2683 ratings)
Curcumin 500 mg
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Score84
A substantial, good-value curcumin phytosome with strong absorption logic, held back mainly by unclear active yield.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Anti-Inflammatory Support
Detoxification
Joint Health
Immunity
Anti-Aging
General Health

Score 84

A substantial, good-value curcumin phytosome with strong absorption logic, held back mainly by unclear active yield.
How scoring works
$19.35($0.32 per serving)
iHerb
$ 22.03
Vitacost
$ 23.35
Daily Vita
$ 20.80
Amazon
$ 19.35
Pure Formulas
$ 21.42
Report prices

Analysis

Phospholipid phytosome delivery improves curcumin's practical absorption compared with a basic extract. The substantial complex amount gives the single-active formula strong relevance to inflammatory and joint-comfort pathways.

The label states total complex weight rather than the active curcuminoid yield. Independent testing and full excipient details are not included in the supplied information.

The focused design avoids low-dose padding and offers good recurring value. It fits targeted curcumin use better than broad general-health or immune coverage.

Who is it for
  • Adults seeking a bioavailability-enhanced curcumin
  • People focused on inflammatory or joint comfort
Best for
  • Anti-inflammatory support
  • Joint-comfort routines
  • Focused antioxidant support

Pros

  • Uses phytosome delivery
  • Substantial complex amount
  • Focused single-active design
  • Favorable qualitative value

Cons

  • Active curcuminoid yield is not disclosed
  • Independent testing is not identified
  • Provides narrow pathway coverage

Warnings

  • Curcumin may increase bleeding tendency with anticoagulant or antiplatelet medicines
  • Curcumin may aggravate bile-duct obstruction or active gallbladder problems
  • Digestive upset or diarrhea can occur in sensitive users

Nutrient quality

91 Highest impact

The substantial phytosome complex uses a delivery form designed to improve absorption. The actual curcuminoid yield and non-active ingredients are not supplied.

Ingredient transparency

77 High impact

Active complex amounts and serving details are stated clearly. The actual curcuminoid yield and non-active ingredients are not supplied.

Customer satisfaction

73 High impact

The supplied average rating is very strong, and a very large response volume makes the average rating more stable. No comment-level feedback is supplied to judge recurring complaints or purpose-specific experiences.

Value for money

94 Highest impact

Focused formulation and low serving cost support strong value. Formula focus and disclosure determine whether that value holds up in practice.

Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A+ Goal FitA- Strength of SupportB- CoverageA+ Formula Quality
Curcumin · 500 mg

Curcumin phytosome at 500 mg is closely aligned with anti-inflammatory support and uses delivery technology intended to improve absorption. Curcumin may influence NF-kB, COX-2, and related signaling.

The actual curcuminoid yield is not disclosed, which limits dose precision. Even so, the enhanced-delivery format and focused formula make the ingredient more convincing than ordinary unenhanced curcumin.

Study evidence
Curcumin Supportive 68 studies
Detoxification
Detoxification
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Curcumin · 500 mg

Curcumin can activate antioxidant-response pathways and support liver-cell protection, giving it meaningful detoxification relevance. Human evidence is stronger for inflammation and metabolic support than for broad toxin clearance.

The phytosome delivery improves absorption and the amount is substantial. Curcumin may increase bleeding tendency with anticoagulant or antiplatelet medicines and can aggravate symptoms when bile flow is obstructed.

Study evidence
Curcumin Supportive 30 studies
Joint Health
Joint Health
Impact
High effect
A- Goal FitC+ Strength of SupportC- CoverageA+ Formula Quality
Curcumin · 500 mg

Curcumin is strongly aligned with joint-comfort pathways, and the phytosome delivery system should improve absorption. Human evidence supports bioavailable curcumin preparations for mobility and comfort.

The label gives the total complex amount but not the actual curcuminoid yield. The formula is focused and free from distracting low-dose additions.

Study evidence
Curcumin Supportive 62 studies
Immunity
Immunity
Impact
High effect
C Goal FitB Strength of SupportD+ CoverageA Formula Quality

Curcumin phytosome may help regulate inflammatory signaling that interacts with immune function. The phytosome delivery improves plausibility compared with ordinary curcumin.

The complex amount is disclosed, but the actual curcuminoid yield is not stated. Its role remains situational and focused on inflammatory balance rather than broad immune readiness.

Study evidence
Curcumin Supportive 10 studies
Anti-Aging
Anti-Aging
Impact
High effect
B Goal FitC Strength of SupportC- CoverageA Formula Quality
Curcumin · 500 mg

Curcumin phytosome directly targets inflammatory and oxidative processes relevant to healthy aging. Human research supports bioavailable curcumin for selected inflammatory and functional outcomes, though broad healthspan effects remain uncertain.

Phytosome delivery should improve absorption over ordinary curcumin powder. The total complex amount is clear, but the active curcuminoid yield and independent quality verification are not disclosed.

Study evidence
Curcumin Supportive 6 studies
General Health
General Health
Impact
High effect
B Goal FitC Strength of SupportD CoverageA Formula Quality
Curcumin · 500 mg

Curcumin can support general wellness through antioxidant and inflammatory-balance pathways. A phytosome delivery system should improve absorption compared with an ordinary curcumin extract.

The label gives the total complex amount but not the actual curcuminoid yield, which makes dose adequacy uncertain. Its single-ingredient design is focused and clean, though it covers a narrower part of general health than a foundational nutrient formula.

Study evidence
Curcumin Supportive 64 studies

Ingredients

IngredientAmount per serving
Curcumin Phytosome (Curcuminoids)
 500 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Curcumin (Curcuminoids) · 500 mg OverallScore60
C+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The phytosome format should improve absorption over an ordinary curcumin extract. The 500 mg complex is clearly listed, but its actual curcuminoid yield and independent testing status are not disclosed. A low serving cost gives it favorable value despite that label uncertainty.

View ingredientView products
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84 Performance

Curcumin C3 Complex

Jigsaw Health
Curcumin C3 Complex provides 500 mg of standardized curcuminoids with unusually clear active disclosure. Its formulation quality and curcumin focus compare favorably with the original, although no separate absorption enhancer is listed.
80 Performance

Cogumin SLCP 400 mg

Protocol For Life Balance
Longvida supplies 400 mg of absorption-oriented curcumin, giving the formula a practical and clearly named delivery system. Its formulation quality and curcumin focus compare favorably with the original, although the active curcuminoid yield remains unclear.
79 Performance

CuraMed Syrup

Terry Naturally
Curcumin remains the main active, but the supplied label does not clearly state its active curcuminoid yield. Its formulation quality and curcumin focus compare favorably with the original, although the active curcuminoid yield remains unclear.
86 Budget

Curcumin Phytosome

Jarrow Formulas
Meriva pairs curcumin with a phospholipid delivery system, which may improve uptake compared with a plain turmeric extract. It is among the closest low-cost supplied choices, but it is not cheaper than the original and the active curcuminoid yield remains unclear.
84 Budget

CurcuBrain 400 mg

NOW
Longvida supplies 400 mg of absorption-oriented curcumin, giving the formula a practical and clearly named delivery system. It is among the closest low-cost supplied choices, but it is not cheaper than the original and the active curcuminoid yield remains unclear.
83 Budget

CurcuVIVA

AOR Advanced Orthomolecular Research Advanced
Longvida supplies 400 mg of absorption-oriented curcumin, giving the formula a practical and clearly named delivery system. It is among the closest low-cost supplied choices, but it is not cheaper than the original and the active curcuminoid yield remains unclear.
82 Value

Theracurmin Double Strength

Natural Factors CurcuminRich
Curcumin remains the main active, but the supplied label does not clearly state its active curcuminoid yield. Useful formulation quality and efficient serving economics create a favorable quality-to-cost balance, although the active curcuminoid yield remains unclear.
81 Value

Curcumin Phytosome 1000 mg Citrus

Codeage Nanofood
A 1,000 mg curcumin phytosome complex combines a substantial serving with phospholipid-based delivery. Useful formulation quality and efficient serving economics create a favorable quality-to-cost balance, although the active curcuminoid yield remains unclear.
79 Value

CurcuminRich Theracurmin

Natural Factors
Curcumin remains the main active, but the supplied label does not clearly state its active curcuminoid yield. Useful formulation quality and efficient serving economics create a favorable quality-to-cost balance, although the active curcuminoid yield remains unclear.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Curcumin on Postmenopausal Women's Health: A Systematic Review and Meta-Analysis.
    Jin D; Jin S; Sheng G; Cui Z; Gao P; Li G · Phytotherapy research : PTR · 2025
    Meta-analysis982 participants14 studies pooledGeneral Health forCurcumin
  2. The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis.
    Sadeghi N; Mansoori A; Shayesteh A; Hashemi SJ · Phytotherapy research : PTR · 2020
    Randomized trial70 participantsGeneral Health forCurcumin
  3. Oral Curcumin No More Effective Than Placebo in Preventing Recurrence of Crohn's Disease After Surgery in a Randomized Controlled Trial.
    Bommelaer G; Laharie D; Nancey S; Hebuterne X; Roblin X; Nachury M; Peyrin-Biroulet L; Fumery M; Richard D; Pereira B; Goutte M; Buisson A; POPCUR study group · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Randomized trial62 participantsGeneral Health forCurcumin
  4. Effect of curcumin on nasal symptoms and airflow in patients with perennial allergic rhinitis.
    Wu S; Xiao D · Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017
    Randomized trial241 participantsImmunity forCurcumin
  5. Effects of curcumin-piperine supplementation on systemic immunity in young women with premenstrual syndrome and dysmenorrhea: A randomized clinical trial.
    Bahrami A; Mohammadifard M; Rajabi Z; Motahari-Nasab M; Ferns GA · European journal of obstetrics, gynecology, and reproductive biology · 2022
    Randomized trial80 participantsImmunity forCurcumin
  6. Immunoregulatory effects of nanocurcumin in inflammatory milieu: Focus on COVID-19.
    Arab FL; Hoseinzadeh A; Mohammadi FS; Rajabian A; Faridzadeh A; Mahmoudi M · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Narrative reviewImmunity forCurcumin
  7. The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis.
    Zeng L; Yu G; Hao W; Yang K; Chen H · Bioscience reports · 2022
    Meta-analysis1,621 participants15 studies pooledJoint Health forCurcumin
  8. Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis.
    Zhao J; Liang G; Zhou G; Hong K; Yang W; Liu J; Zeng L · Journal of ethnopharmacology · 2024
    Meta-analysis2,175 participants23 studies pooledJoint Health forCurcumin
  9. The Oral Administration of Highly-Bioavailable Curcumin for One Year Has Clinical and Chondro-Protective Effects: A Randomized, Double-Blinded, Placebo-Controlled Prospective Study.
    Nakagawa Y; Mori K; Yamada S; Mukai S; Hirose A; Nakamura R · Arthroscopy, sports medicine, and rehabilitation · 2022
    Randomized trial50 participantsJoint Health forCurcumin
  10. Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial.
    Rahimnia AR; Panahi Y; Alishiri G; Sharafi M; Sahebkar A · Drug research · 2016
    Randomized trial40 participantsJoint Health forCurcumin
  11. Effect of curcumin on C-reactive protein as a biomarker of systemic inflammation: An updated meta-analysis of randomized controlled trials.
    Gorabi AM; Abbasifard M; Imani D; Aslani S; Razi B; Alizadeh S; Bagheri-Hosseinabadi Z; Sathyapalan T; Sahebkar A · Phytotherapy research : PTR · 2022
    Meta-analysis32 studies pooledAnti-Inflammatory Support forCurcumin
  12. Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? Evidence from a meta-analysis.
    Sahebkar A · Phytotherapy research : PTR · 2014
    Meta-analysis342 participants6 studies pooledAnti-Inflammatory Support forCurcumin
  13. Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis.
    Zhang Y; Huang L; Zhang J; De Souza Rastelli AN; Yang J; Deng D · Frontiers in pharmacology · 2024
    Meta-analysis846 participants18 studies pooledAnti-Inflammatory Support forCurcumin
  14. Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials.
    Derosa G; Maffioli P; Simental-Mendía LE; Bo S; Sahebkar A · Pharmacological research · 2018
    Meta-analysis9 studies pooledAnti-Inflammatory Support forCurcumin
  15. Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials.
    White CM; Pasupuleti V; Roman YM; Li Y; Hernandez AV · Pharmacological research · 2020
    Meta-analysis1,344 participants19 studies pooledAnti-Inflammatory Support forCurcumin
  16. Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study.
    Cox KHM; White DJ; Pipingas A; Poorun K; Scholey A · Nutrients · 2021
    Randomized trial80 participantsAnti-Aging forCurcumin
  17. Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women.
    Akazawa N; Choi Y; Miyaki A; Tanabe Y; Sugawara J; Ajisaka R; Maeda S · Nutrition research (New York, N.Y.) · 2013
    Clinical trial32 participantsAnti-Aging forCurcumin
  18. A novel phospholipid delivery system of curcumin (Meriva®) preserves muscular mass in healthy aging subjects.
    Franceschi F; Feregalli B; Togni S; Cornelli U; Giacomelli L; Eggenhoffner R; Belcaro G · European review for medical and pharmacological sciences · 2016
    Non-randomized trial86 participantsAnti-Aging forCurcumin
  19. Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence.
    Nunes YC; Mendes NM; Pereira de Lima E; Chehadi AC; Lamas CB; Haber JFS; Dos Santos Bueno M; Araújo AC; Catharin VCS; Detregiachi CRP; Laurindo LF; Tanaka M; Barbalho SM; Marin MJS · Nutrients · 2024
    Systematic review15 studies pooledAnti-Aging forCurcumin
  20. Curcumin and arterial function in health and disease: impact on oxidative stress and inflammation.
    Fleenor BS; Carlini NA; Campbell MS · Current opinion in clinical nutrition and metabolic care · 2020
    Narrative reviewAnti-Aging forCurcumin
  21. Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.
    Zhang F; Niu B · Medicine · 2025
    Meta-analysis7 studies pooledAnti-Inflammatory Support forCurcumin
  22. Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial.
    Jazayeri-Tehrani SA; Rezayat SM; Mansouri S; Qorbani M; Alavian SM; Daneshi-Maskooni M; Hosseinzadeh-Attar MJ · Nutrition & metabolism · 2024
    Randomized trial84 participantsAnti-Inflammatory Support Detoxification forCurcumin
  23. Is Curcumin Intake Really Effective for Chronic Inflammatory Metabolic Disease? A Review of Meta-Analyses of Randomized Controlled Trials.
    Lee YM; Kim Y · Nutrients · 2024
    Systematic review54 studies pooledAnti-Inflammatory Support forCurcumin
  24. Curcumin supplementation effect on liver enzymes in patients with nonalcoholic fatty liver disease: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.
    Vajdi M; Hassanizadeh S; Hassanizadeh R; Bagherniya M · Nutrition reviews · 2024
    Meta-analysis905 participants15 studies pooledDetoxification forCurcumin
  25. Therapeutic effects of curcumin supplementation on liver enzymes of nonalcoholic fatty liver disease patients: A systematic review and meta-analysis of randomized clinical trials.
    Ebrahimzadeh A; Ebrahimzadeh A; Fooladshekan S; Mohseni S; Mohtashamian A; Babajafari S; Sohrabi Z · Food science & nutrition · 2025
    Meta-analysis14 studies pooledDetoxification forCurcumin
  26. Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.
    Yaikwawong M; Kamdee K; Chuengsamarn S · International journal of molecular sciences · 2025
    Randomized trial227 participantsDetoxification forCurcumin
  27. A Novel Curcumin-Galactomannoside Complex Delivery System Improves Hepatic Function Markers in Chronic Alcoholics: A Double-Blinded, randomized, Placebo-Controlled Study.
    T Krishnareddy N; Thomas JV; Nair SS; N Mulakal J; Maliakel BP; Krishnakumar IM · BioMed research international · 2019
    Randomized trial48 participantsDetoxification forCurcumin
  28. The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial.
    Parohan M; Sarraf P; Javanbakht MH; Foroushani AR; Ranji-Burachaloo S; Djalali M · Nutritional neuroscience · 2021
    Randomized trial100 participantsGeneral Health forCurcumin
  29. Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Prasad N; Agarwal Y · Journal of pain research · 2025
    Randomized trial139 participantsGeneral Health forCurcumin
  30. Effectiveness of curcuminoids in the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomized clinical trials.
    Onakpoya IJ; Spencer EA; Perera R; Heneghan CJ · International journal of rheumatic diseases · 2018
    Meta-analysis797 participants7 studies pooledGeneral Health forCurcumin
  31. Effectiveness and safety of turmeric for the treatment of COVID-19: An updated systematic review and meta-analysis of randomized controlled trials.
    Sawangjit R; Sadoyu S; Manosanthipaibul S; Teerawattanapong N; Puttarak P; Wanaratna K; Charoensup R; Hiransai P; Meetam T; Chaiyakunapruk N · Complementary therapies in medicine · 2025
    Meta-analysis1,407 participants23 studies pooledGeneral Health forCurcumin
  32. Effects of Highly Bioavailable Curcumin Supplementation on Common Cold Symptoms and Immune and Inflammatory Functions in Healthy Japanese Subjects: A Randomized Controlled Study.
    Kuwabara Y; Hirose A; Lee H; Kakinuma T; Baba A; Takara T · Journal of dietary supplements · 2023
    Randomized trial99 participantsImmunity forCurcumin
  33. The roles of curcumin in regulating the tumor immunosuppressive microenvironment.
    Wang Y; Lu J; Jiang B; Guo J · Oncology letters · 2020
    Narrative reviewImmunity forCurcumin
  34. Neuroprotective Activities of Curcumin in Parkinson's Disease: A Review of the Literature.
    Nebrisi EE · International journal of molecular sciences · 2021
    Narrative reviewImmunity forCurcumin
  35. Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.
    Zeng L; Yang T; Yang K; Yu G; Li J; Xiang W; Chen H · Frontiers in immunology · 2022
    Meta-analysis2,396 participants29 studies pooledJoint Health forCurcumin
  36. The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses.
    Bideshki MV; Jourabchi-Ghadim N; Radkhah N; Behzadi M; Asemani S; Jamilian P; Zarezadeh M · Phytotherapy research : PTR · 2024
    Meta-analysis11 studies pooledJoint Health forCurcumin
  37. The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis.
    Hsiao AF; Lien YC; Tzeng IS; Liu CT; Chou SH; Horng YS · Complementary therapies in medicine · 2021
    Meta-analysis1,258 participants11 studies pooledJoint Health forCurcumin