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CoQ10 100 mg

Lake Avenue Nutrition
4.8
★ ★ ★ ★ ★
(75926 ratings)
Coenzyme Q-10 100 mg
Product Image
Score86
CoQ10 100 mg provides 100 mg of ubiquinone with excellent serving value. The dry capsule lacks a lipid carrier, so absorption depends more on taking it with food containing fat.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Energy
Heart Health
Anti-Aging
Cardiovascular Support
Metabolism Boost
Anti-Inflammatory Support

Score 86

CoQ10 100 mg provides 100 mg of ubiquinone with excellent serving value. The dry capsule lacks a lipid carrier, so absorption depends more on taking it with food containing fat.
How scoring works
$15.07($0.12 per serving)
iHerb
$ 15.07
iHerb
$ 15.07
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Analysis

The identified ubiquinone form and maintenance amount are easy to assess and provide very strong value. The serving provides 100 mg of ubiquinone in a dry capsule.

CoQ10 supports cellular energy production and antioxidant defenses. Ubiquinone is a clearly identified and widely used maintenance form of CoQ10. Because CoQ10 is fat-soluble, this dry format depends more on being taken with a meal containing fat.

The dry capsule lacks a lipid carrier, so absorption depends more on taking it with food containing fat. The 120-serving supply offers excellent serving value, so form, delivery, and intended dose should guide the choice.

Who is it for
  • Adults seeking 100 mg of CoQ10
  • People who prefer a dry capsule format
  • Users who want a focused CoQ10 formula
Best for
  • Cellular energy support
  • Antioxidant support
  • Routine CoQ10 supplementation

Pros

  • 100 mg CoQ10 amount is fully disclosed
  • Ubiquinone identifies the active form
  • 120 servings per container
  • Excellent serving value

Cons

  • The dry capsule lacks a lipid carrier, so absorption depends more on taking it with food containing fat.
  • Taking the capsule with a fat-containing meal is more important than with an oil-based softgel.
  • The focused formula provides limited coverage beyond mitochondrial and antioxidant support.

Warnings

  • CoQ10 may reduce the effect of warfarin, so anticoagulation should be monitored by the prescriber when use starts, stops, or changes.
  • The dry capsule has no lipid carrier, so taking it without food containing fat may reduce absorption.
  • Count the 100 mg CoQ10 serving when combining it with another ubiquinol or ubiquinone product.

Nutrient quality

89 Highest impact

Ubiquinone is clearly identified, but the dry capsule lacks a lipid carrier for this fat-soluble active. The 100 mg amount is meaningful for routine CoQ10 use.

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Ingredient transparency

83 Highest impact

Active ingredients have stated amounts and no proprietary blend hides a dose. Serving count is supplied, while full directions and the other-ingredients list are missing.

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Customer satisfaction

73 High impact

The supplied aggregate rating is the only evidence of general satisfaction and its reliability depends on rating volume. No comment-level evidence is available to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

98 Highest impact

The effective amount and favorable serving cost strongly support formula value. The product compares very well with similar CoQ10 options.

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Goals

Energy
Impact
Highest effect
A Goal FitB+ Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinone provides a practical CoQ10 amount for mitochondrial ATP production. The single-capsule design is transparent and stimulant free.

A dry capsule lacks the lipid carrier that can improve absorption of this fat-soluble compound. Taking it with a meal containing fat may improve uptake, while the formula remains focused on one energy pathway.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Heart Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinone CoQ10 directly supports cardiac mitochondrial energy at a useful maintenance amount. The simple capsule is strongly heart relevant but does not add vascular-tone or lipid pathways.

The molecular form and exact amount are clear, though the dry capsule lacks a lipid carrier. CoQ10 can alter warfarin response, so anticoagulation may need closer monitoring when starting or stopping it.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Anti-Aging
Impact
Highest effect
A- Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 at 100 mg directly supports mitochondrial energy production and antioxidant defense, both relevant to biological aging. Ubiquinone is clearly identified, but the dry capsule lacks a lipid carrier or absorption enhancer.

The formula does not address structural aging, glycation, or inflammation through separate actives. CoQ10 may reduce the anticoagulant effect of warfarin, so users of that medicine need prescriber guidance.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Cardiovascular Support
Impact
Highest effect
A- Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production in heart muscle and may be especially relevant when statin therapy lowers CoQ10 status. The single active does not address lipids, vasodilation, rhythm minerals, or homocysteine.

The 100 mg amount is meaningful and fully disclosed, but ubiquinone generally has less absorption advantage than ubiquinol. The focused design makes the product easy to assess.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Metabolism Boost
Impact
High effect
B+ Goal FitC+ Strength of SupportC- CoverageA- Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 provides focused support for mitochondrial energy production at a useful maintenance amount. Human evidence supports mitochondrial function more clearly than a direct rise in metabolic rate.

The dry capsule lacks a lipid carrier for the fat-soluble active and may absorb less consistently. The single-pathway design offers depth but little functional breadth.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB- Strength of SupportD CoverageA- Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 provides useful mitochondrial antioxidant support that may help moderate inflammation linked to oxidative stress. The clearly stated ubiquinone amount is practical for routine use.

The dry capsule has no stated lipid carrier or absorption enhancer, which limits confidence in uptake. Its single-ingredient focus also leaves direct inflammatory enzyme and immune-signaling pathways uncovered.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Coenzyme Q-10 (Ubiquinone)
100 mg
Gluten Free Adults 18–50 Dairy Free No Allergies
Report overview
D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

Ubiquinone is supplied in a practical maintenance amount with clear single-capsule dosing. The dry capsule lacks a lipid carrier or absorption enhancer, so taking it with a fat-containing meal may improve uptake. Its very low serving cost offers excellent value despite the basic delivery system.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  2. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  3. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  4. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  5. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  6. Can coenzyme q10 improve clinical and molecular parameters in fibromyalgia?
    Cordero MD; Alcocer-Gómez E; de Miguel M; Culic O; Carrión AM; Alvarez-Suarez JM; Bullón P; Battino M; Fernández-Rodríguez A; Sánchez-Alcazar JA · Antioxidants & redox signaling · 2014
    Randomized trial20 participantsEnergy forCoenzyme Q-10
  7. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  8. Coenzyme Q10 supplementation in rheumatic diseases: A systematic review.
    Freire de Carvalho J; Skare T · Clinical nutrition ESPEN · 2024
    Systematic review483 participants20 studies pooledEnergy forCoenzyme Q-10
  9. Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome.
    Fukuda S; Nojima J; Kajimoto O; Yamaguti K; Nakatomi Y; Kuratsune H; Watanabe Y · BioFactors (Oxford, England) · 2017
    Randomized trial63 participantsEnergy forCoenzyme Q-10
  10. Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals.
    Mizuno K; Sasaki AT; Watanabe K; Watanabe Y · Nutrients · 2021
    Clinical trial62 participantsEnergy forCoenzyme Q-10
  11. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  12. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  13. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  14. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  15. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  16. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  17. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  18. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  19. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  20. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  21. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  22. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  23. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  24. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  25. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  26. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  27. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  28. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  29. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  30. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  31. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  32. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  33. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  34. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  35. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10