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Selenium 200 mcg

Thorne
4.8
★ ★ ★ ★ ★
(15222 ratings)
Selenium 200 mcg
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Score85
A focused, clearly dosed selenium supplement using L-selenomethionine. It offers good value, but the substantial amount should not be casually stacked.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
General Health
Immunity

Score 85

A focused, clearly dosed selenium supplement using L-selenomethionine. It offers good value, but the substantial amount should not be casually stacked.
How scoring works
$14.00($0.23 per serving)
Pure Formulas
$ 14.00
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$ 14.00
Amazon
$ 14.00
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$ 14.00
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Walmart
$ 14.00
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Analysis

The single active provides 200 mcg of selenium, a substantial supplemental amount that supports antioxidant enzymes and normal thyroid function. L-selenomethionine is a well-absorbed organic form with a clear chemical identity.

A one-ingredient formula is easy to fit around other supplements and avoids unrelated actives. Its narrow scope also means it is useful only when selenium is the specific nutrient being targeted.

One capsule per serving keeps use simple, and good value strengthens the practical case. The amount is high enough that overlap with multivitamins and other selenium products needs attention.

Who is it for
  • Adults specifically seeking selenium support
  • People who prefer a simple single-active formula
Best for
  • Targeted selenium intake
  • Antioxidant-enzyme support
  • Filling a known selenium gap

Pros

  • Uses L-selenomethionine
  • Clearly discloses the 200 mcg amount
  • Simple one-capsule serving
  • Offers good value

Cons

  • Provides only one nutrient
  • Amount may be unnecessary for people with adequate selenium intake
  • No complementary nutrients

Warnings

  • Two hundred micrograms is a substantial amount, so it should not be combined casually with another selenium supplement or a high-selenium multivitamin.
  • Chronic excess selenium can cause brittle hair or nails, nausea, or a garlic-like breath odor; these signs warrant stopping use and seeking advice.
  • People already being treated for a thyroid disorder should account for total selenium intake with their clinician rather than adding a high-dose product automatically.

Nutrient quality

91 Highest impact

L-selenomethionine is a preferred organic form with clear isomer disclosure. The selenium amount remains below the adult upper limit but requires accounting for other selenium sources.

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Ingredient transparency

83 Highest impact

The selenium amount and source are clearly stated. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

73 High impact

The supplied aggregate rating indicates very strong customer satisfaction. Specific comments are unavailable, so complaint patterns and intended-use fit cannot be verified.

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Value for money

91 Highest impact

Preferred form quality and a modest serving cost create strong value. The simple capsule compares favorably within the category.

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Goals

General Health
Impact
Highest effect
A Goal FitA+ Strength of SupportB CoverageA+ Formula Quality
Selenium · 200 mcg

Selenium as L-selenomethionine provides focused support for antioxidant enzymes, thyroid hormone conversion, and immune function. The well-absorbed form and exact amount are clearly disclosed.

The formula offers strong depth for one essential trace mineral but does not cover other nutritional gaps. Users taking other selenium products should account for the combined intake because excess selenium can cause hair, nail, and digestive changes.

Study evidence
Selenium Supportive 70 studies
Immunity
Impact
Highest effect
A- Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Selenium · 200 mcg

Selenium supports antioxidant enzymes and normal immune-cell function at a substantial amount. L-selenomethionine is a clearly identified and well-absorbed organic form.

The focused formula provides strong depth for selenium-dependent defenses. It remains narrow because no barrier nutrients or other direct immune actives are included.

Study evidence
Selenium Mixed 37 studies

Ingredients

IngredientAmount per serving
Selenium (L-Selenomethionine)
200 mcg
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

L-selenomethionine provides a well-absorbed organic selenium source with clear isomer labeling. The 200 mcg serving aligns with common targeted use and stays below the adult upper intake level. Its low serving cost provides favorable selenium-specific value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  6. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  7. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  8. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  9. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  10. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium