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Se-Methyl L-Selenocysteine 200 mcg

Life Extension
4.9
★ ★ ★ ★ ★
(3227 ratings)
Selenium 200 mcg
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Score87
A focused 200 mcg selenium capsule using Se-methyl L-selenocysteine, with clear dosing but incomplete non-active ingredient details.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
General Health
Immunity

Score 87

A focused 200 mcg selenium capsule using Se-methyl L-selenocysteine, with clear dosing but incomplete non-active ingredient details.
How scoring works
$8.25($0.09 per serving)
Pure Formulas
$ 8.25
Vitacost
$ 8.25
Amazon
$ 8.25
iHerb
$ 8.25
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Analysis

Se-Methyl L-Selenocysteine provides 200 mcg selenium as Se-methyl L-selenocysteine. The narrow formula makes its purpose and daily contribution easy to understand.

The explicitly named organic form is a transparency strength. The supplied details do not include non-active ingredients, so capsule or tablet suitability cannot be fully checked.

The focused capsule offers favorable routine value. The dose should still be considered alongside selenium from food and other supplements.

Who is it for
  • Adults intentionally adding selenium
  • People who prefer a capsule format
Best for
  • Targeted selenium intake
  • Simple supplement routines

Pros

  • Clearly states 200 mcg selenium
  • Uses Se-methyl L-selenocysteine
  • The focused capsule offers favorable routine value.

Cons

  • Non-active ingredients are not supplied
  • Narrow single-nutrient formula
  • Requires care when stacking supplements

Warnings

  • Count the 200 mcg selenium serving with multivitamins and other selenium products to avoid unnecessary excess.

Nutrient quality

94 Highest impact

A clearly identified organic form and meaningful amount support dependable selenium intake. The formula is precise and filler-free, although total selenium from other products still matters.

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Ingredient transparency

84 Highest impact

The active form and amount are clearly identified without a hidden blend. Explicit use directions and non-active ingredients are absent from the supplied data.

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Customer satisfaction

71 High impact

The available rating is strong and the sample is large. Detailed feedback was not supplied, so repeated complaints and alignment with the intended use remain uncertain.

.

Value for money

99 Highest impact

A premium organic form and long supply deliver excellent practical value. The focused formula avoids extras that could dilute the value.

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Goals

General Health
General Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Selenium · 200 mcg

Selenium directly supports antioxidant enzymes, thyroid hormone metabolism, and immune function. The 200 mcg amount is meaningful while leaving a sensible margin below the daily upper limit.

Se-methyl L-selenocysteine is a clearly identified organic form with strong absorption potential. The single-ingredient design is precise and well suited to targeted selenium support.

Study evidence
Selenium Supportive 70 studies
Immunity
Immunity
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC- CoverageA Formula Quality
Selenium · 200 mcg

Selenium supports foundational antioxidant enzymes and normal thyroid function. The formula mainly supports selenium-dependent antioxidant and thyroid pathways rather than broad nutrition.

The disclosed selenium amount is suitable for focused daily maintenance without approaching the adult upper limit. The label clearly identifies the selenium form and amount, supporting straightforward assessment.

Study evidence
Selenium Mixed 37 studies

Ingredients

IngredientAmount per serving
Selenium (Se-Methyl L-Selenocysteine)
 200 mcg
Adults 18–50
Report overview
Selenium (Se-Methyl L-Selenocysteine) · 200 mcg OverallScore100
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Se-methyl L-selenocysteine is a clearly identified organic form with strong absorption and retention characteristics. The serving matches the preferred target while keeping a useful margin below the daily upper limit. Its low standardized cost combines precise disclosure with excellent practical value.

View ingredientView products
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Selenium 200 mcg

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<p>Its label clearly provides 37 mg of Calcium as Dibasic Calcium Phosphate, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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<p>Its label clearly provides 200 mcg of Selenium as L-Se-Methylselenocysteine, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  6. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  7. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  8. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  9. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  10. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium