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CoQ10 400 mg

Protocol For Life Balance
4.8
★ ★ ★ ★ ★
(138 ratings)
Coenzyme Q-10 400 mg
Vitamin E 30 IU
Product Image
Score77
A single softgel delivers high-dose CoQ10 with vitamin E and sunflower lecithin. Unspecified active form and premium cost are the main drawbacks.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Heart Health
Anti-Aging
Anti-Inflammatory Support
Energy
Cardiovascular Support
Metabolism Boost

Score 77

A single softgel delivers high-dose CoQ10 with vitamin E and sunflower lecithin. Unspecified active form and premium cost are the main drawbacks.
How scoring works
$65.00($1.08 per serving)
iHerb
$ 65.00
Pure Formulas
$ 65.00
Vitacost
$ 65.00
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Analysis

The one-softgel serving supplies a substantial 400 mg CoQ10 amount with natural vitamin E. Sunflower lecithin supports an oil-compatible formula without soy lecithin.

The label does not identify ubiquinone or ubiquinol, leaving absorption characteristics uncertain. The dose is more suited to a deliberate high-dose plan than basic maintenance.

The product fits adults seeking concentrated CoQ10 in one softgel and avoiding soy lecithin. Users who want a conservative amount or clearly identified form have more precise choices.

Who is it for
  • Adults seeking high-dose CoQ10
  • Users avoiding soy lecithin
  • People who prefer one softgel
Best for
  • Concentrated CoQ10 use
  • A soy-free lecithin choice
  • High-dose one-softgel convenience

Pros

  • Provides 400 mg CoQ10
  • One-softgel serving
  • Includes natural vitamin E
  • Uses sunflower lecithin

Cons

  • CoQ10 form is not identified
  • No named absorption technology
  • Amount may exceed routine needs
  • High serving cost

Warnings

  • CoQ10 may lower blood pressure alongside antihypertensive medicine
  • CoQ10 can affect warfarin response and may require closer anticoagulation monitoring
  • High-dose CoQ10 may cause stomach upset or sleep disruption in sensitive users

Nutrient quality

85 Highest impact

Vitamin E and sunflower lecithin support fat-soluble delivery, though the coenzyme Q10 form is not specified. Coenzyme Q10 is supplied at a large amount suited to targeted use.

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Ingredient transparency

81 Highest impact

The coenzyme Q10 amount is clear, but the label does not distinguish ubiquinone from ubiquinol. Complete non-active ingredient details are not included in the supplied label data.

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Customer satisfaction

67 High impact

The supplied average rating provides limited high-level context. Detailed firsthand feedback is unavailable, so recurring complaints and purpose fit cannot be assessed.

.

Value for money

72 High impact

The large dose partly justifies the premium cost for targeted use. Dose-adjusted value is reasonable, though many users may not need this amount.

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Goals

Heart Health
Heart Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mg

The 400 mg CoQ10 amount provides strong, focused support for cardiac cellular energy and antioxidant protection. Human evidence is relevant for people with higher needs, including those whose CoQ10 status may be affected by statin use.

The oil-based softgel should support absorption, although the form is standard ubiquinone rather than ubiquinol. The high amount is clearly disclosed and is not diluted by unrelated ingredients.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mg

A high CoQ10 amount directly supports mitochondrial energy and antioxidant protection relevant to healthy aging. Vitamin E and sunflower lecithin complement this fat-soluble active, though the label does not identify ubiquinone or ubiquinol.

The softgel and lecithin support absorption, and every active amount is clearly stated. CoQ10 can reduce warfarin response in some users, so anticoagulation should be monitored when use changes.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Vitamin E Supportive 19 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A- Goal FitA Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mgVitamin E · 30 IU

CoQ10 supports mitochondrial antioxidant control, while vitamin E adds lipid-phase antioxidant protection. Human evidence supports CoQ10 effects on selected inflammatory markers and established antioxidant activity from vitamin E.

The 400 mg CoQ10 amount provides a high supplemental exposure. Exact amounts are clear, and sunflower lecithin may aid dispersion, though the CoQ10 redox form is not stated. The 400 mg CoQ10 amount may cause stomach upset and can reduce warfarin's anticoagulant effect.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Vitamin E Supportive 20 studies
Energy
Energy
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mg

CoQ10 directly supports mitochondrial ATP production and is especially relevant when levels are low, including with aging or statin use. The high amount gives this focused formula strong depth rather than broad pathway coverage.

Softgel delivery with lecithin supports absorption, but the label does not identify whether the active is ubiquinone or ubiquinol. The formula is lean and well aligned, though benefits may be less noticeable in people who already have adequate CoQ10 status.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitA- Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mgVitamin E · 30 IU

The 400 mg CoQ10 amount provides deep support for cardiac energy production and antioxidant defense. Natural vitamin E and sunflower lecithin complement the central active and may help protect or disperse it.

The CoQ10 molecular form is not specified, so absorption cannot be compared with ubiquinol. CoQ10 may reduce warfarin’s anticoagulant effect, making monitoring important for people using that medicine.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Vitamin E Mixed 79 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 400 mg

CoQ10 supports mitochondrial energy production at a high amount. It may support cellular energy efficiency but is not a direct thermogenic stimulant.

CoQ10 with an unspecified molecular form is delivered in a lecithin-containing softgel. The formula does not address thyroid, glucose, or stimulant pathways.

Study evidence
Coenzyme Q-10 Disputed 11 studies

Ingredients

IngredientAmount per serving
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Vitamin E (D-Alpha-Tocopherol)
 30 IU
Coenzyme Q10
400 mg
Sunflower Lecithin
35 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 · 400 mg OverallScore64
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

A high, well-supported CoQ10 amount is delivered in a softgel with sunflower lecithin. The molecular form is not identified, so the product cannot claim the absorption advantage of ubiquinol. Strong delivery and dose quality are offset by a relatively high serving cost.

View ingredientView products
Vitamin E (D-Alpha-Tocopherol) · 30 IU OverallScore59
D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD- Value

Natural d-alpha-tocopherol is clearly identified, but the serving provides only a maintenance amount. The vitamin E profile contains neither mixed tocopherols nor tocotrienols. A high serving cost limits value for vitamin E use.

View ingredientView products
Loading alternative details
87 Performance

Mega CoQ10 Ubiquinol 100 mg

Qunol
<p>Its 100 mg of ubiquinol supplies CoQ10 in a different form and includes 6 mg of ascorbyl palmitate. The ubiquinol form gives a more clearly specified formulation than the original’s generically listed CoQ10.</p>
85 Performance

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg

Life Extension
<p>Its 100 mg of ubiquinol is paired with 100 mg of a shilajit fulvic acid complex. The ubiquinol form gives a more clearly specified formulation than the original’s generically listed CoQ10.</p>
87 Performance

QH-absorb 100 mg

Jarrow Formulas
<p>Its focused formula provides 100 mg of ubiquinol without unrelated listed active ingredients. The ubiquinol form gives a more clearly specified formulation than the original’s generically listed CoQ10.</p>
87 Budget

Extra Strength Ubiquinol 200 mg

NOW
<p>It is a more economical CoQ10 option with a lower cost per serving. Its 200 mg of ubiquinol provides twice the CoQ10 amount of a typical 100 mg option in the reduced form. The lower dose is not equivalent to the original’s 400 mg CoQ10 dose, but it may better suit routine use when that unusually high amount is unnecessary.</p>
87 Budget

CoQ10 200 mg

California Gold Nutrition
<p>It is a more economical CoQ10 option with a lower cost per serving. Its 200 mg of ubiquinone doubles the amount in a 100 mg serving while retaining a simple, single-active formula. The lower dose is not equivalent to the original’s 400 mg CoQ10 dose, but it may better suit routine use when that unusually high amount is unnecessary.</p>
84 Budget

High Absorption CoQ10 200 mg

Doctor's Best
<p>It is a more economical CoQ10 option with a lower cost per serving. Its 200 mg of ubiquinone is paired with 5 mg of piperine, an ingredient included to support absorption. The lower dose is not equivalent to the original’s 400 mg CoQ10 dose, but it may better suit routine use when that unusually high amount is unnecessary.</p>
84 Value

CoQ10 200 mg

Nature Made
<p>Its single-active formula supplies 200 mg of CoQ10 as ubidecarenone. The 200 mg amount offers more CoQ10 per serving than many lower-dose options, while the serving cost remains moderate for the formula.</p>
85 Value

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
<p>Its 100 mg of ubiquinone is paired with 5 mg of piperine, adding an absorption-focused ingredient. The focused dose and strong formulation fit provide a useful balance of CoQ10 support and ongoing value compared with the original’s 400 mg CoQ10 dose.</p>
83 Value

CoQ10 100 mg

Healthy Origins
<p>Its simple formula provides 100 mg of ubiquinone with no other listed active ingredients. The focused dose and strong formulation fit provide a useful balance of CoQ10 support and ongoing value compared with the original’s 400 mg CoQ10 dose.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  4. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  5. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  6. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  7. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  8. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  9. Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis.
    Aragón-Vela J; Huertas JR; Casuso RA · Nutrition reviews · 2026
    Meta-analysis1,425 participants52 studies pooledCardiovascular Support forVitamin E
  10. A systematic review and meta-analysis on the impact of oral vitamin E supplementation on apolipoproteins A1 and B100.
    Hamedi-Kalajahi F; Zarezadeh M; Dehghani A; Musazadeh V; Kolahi A; Shabbidar S; Djafarian K · Clinical nutrition ESPEN · 2022
    Meta-analysis1,284 participants7 studies pooledCardiovascular Support forVitamin E
  11. The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
    Ward NC; Wu JH; Clarke MW; Puddey IB; Burke V; Croft KD; Hodgson JM · Journal of hypertension · 2007
    Randomized trial58 participantsCardiovascular Support forVitamin E
  12. Effect of vitamin E on cardiometabolic factors in paediatric metabolic dysfunction-associated steatotic liver disease: a systematic review with meta-analysis.
    Pam P; Musazadeh V; Mahmoudinezhad M; Panahiyan P; Mansoori MA; Zarrin R; Faghfouri AH · The British journal of nutrition · 2026
    Meta-analysis665 participants11 studies pooledCardiovascular Support forVitamin E
  13. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  14. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  15. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  16. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis.
    Sahebkar A; Simental-Mendía LE; Stefanutti C; Pirro M · Pharmacological research · 2016
    Meta-analysis409 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  17. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  18. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  19. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  20. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  21. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  22. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  23. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  24. Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
    Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
    Cohort study1,550 participantsAnti-Aging forVitamin E
  25. Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
    Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
    Cohort study960 participantsAnti-Aging forVitamin E
  26. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
    Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-Díaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-Martínez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Observational study1,002 participantsAnti-Aging forVitamin E
  27. The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
    Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
    Cross-sectional study16,395 participantsAnti-Aging forVitamin E
  28. Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
    Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
    Cohort study140 participantsAnti-Aging forVitamin E
  29. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  30. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  31. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  32. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  33. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  34. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  35. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  36. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  37. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  38. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  39. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  40. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  41. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  42. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  43. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  44. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  45. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  46. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  47. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  48. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  49. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  50. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  51. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  52. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10