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Melatonin 2.5 mg Peppermint Flavor

Source Naturals Sleep Science
4.6
★ ★ ★ ★ ★
(1256 ratings)
Melatonin 2.5 mg
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Score87
A focused dissolving melatonin formula with active-form vitamin B6 and a moderate 2.5 mg amount. It targets sleep onset rather than overnight maintenance.
How scoring works
Quantity:60 Liquid(s) • (60 servings)
Goals:
Sleep Support

Score 87

A focused dissolving melatonin formula with active-form vitamin B6 and a moderate 2.5 mg amount. It targets sleep onset rather than overnight maintenance.
How scoring works
$6.48($0.10 per serving)
Pure Formulas
$ 11.89
Vitacost
$ 6.48
iHerb
$ 6.48
iHerb
$ 6.48
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Analysis

Melatonin is provided at 2.5 mg, a moderate amount that may help with sleep onset or circadian timing. A small amount of pyridoxal 5-phosphate adds active-form vitamin B6 without distracting from the core purpose.

Dissolving delivery may suit users who dislike swallowing tablets, but no sustained-release feature is shown. The dose can still be more than some sensitive users need and is not easily reduced if the format cannot be divided accurately.

The simple formula is practical for occasional sleep-onset use. People prone to morning grogginess should start conservatively and avoid taking it when a full night of sleep is not available.

Who is it for
  • Adults seeking moderate-dose sleep-onset support
  • People who prefer a dissolving format
  • Users who tolerate melatonin without morning grogginess
Best for
  • Sleep-onset support
  • Circadian-timing support
  • A simple melatonin formula with active vitamin B6

Pros

  • Provides a clearly stated 2.5 mg amount
  • Uses pyridoxal 5-phosphate
  • Simple two-active formula
  • Dissolving delivery is convenient

Cons

  • No sustained-release feature
  • Dose may still be high for sensitive users
  • Vitamin B6 adds little to the central sleep purpose

Warnings

  • The 2.5 mg melatonin serving may cause morning grogginess, vivid dreams, headache, or impaired alertness
  • Do not combine melatonin with alcohol, sedatives, or other sleep products without professional guidance
  • Do not drive or operate machinery after taking it
  • Pregnant or breastfeeding users should seek medical guidance before using melatonin

Nutrient quality

90 Highest impact

The modest melatonin amount is meaningful for sleep timing without looking aggressive. Liquid delivery is practical, and the well-regarded P5P vitamin form avoids a weak secondary active.

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Ingredient transparency

90 Highest impact

Active amounts and ingredient names are clearly stated without a proprietary blend. Serving information is straightforward, but the supplied data does not show a separate excipient list.

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Customer satisfaction

69 High impact

The supplied average rating and rating volume indicate reasonably supported satisfaction. No issue-level feedback was supplied, so repeated complaints or purpose fit cannot be verified.

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Value for money

95 Highest impact

The serving cost is favorable for a focused melatonin formula. Minimal low-value additions help it compare well with similar products.

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Goals

Sleep Support
Impact
Highest effect
A+ Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Melatonin · 2.5 mg

The dissolving lozenge may support prompt use for sleep onset. It provides a clearly disclosed 2.5 mg melatonin amount for a defined sleep-related pathway.

The amount is above the lowest physiological range and the formula does not provide overnight release. Sensitive users may still notice morning drowsiness from the 2.5 mg amount.

Study evidence
Melatonin Supportive 181 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxal 5-Phosphate)
335 mcg
Melatonin
2.5 mg
Adults 18–50 Women
Report overview
Melatonin · 2.5 mg OverallScore73
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The dissolving lozenge format may support a relatively quick onset for sleep initiation. The modest single-unit melatonin amount is easy to understand and aligns well with physiological dosing. Lack of sustained-release technology and independent purity verification are the main limitations, while the serving cost remains competitive.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  4. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  5. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  6. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  9. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  10. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin