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Dry-E & Selenium

Bluebonnet
4.6
★ ★ ★ ★ ★
(264 ratings)
Selenium 200 mcg
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Score78
Clear forms and a simple one-capsule design are strengths. High vitamin E and substantial selenium require deliberate use and careful stacking.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
General Health
Immunity

Score 78

Clear forms and a simple one-capsule design are strengths. High vitamin E and substantial selenium require deliberate use and careful stacking.
How scoring works
$31.60($0.26 per serving)
Amazon
$ 38.80
iHerb
$ 31.60
Daily Vita
$ 38.80
Vitacost
$ 38.80
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Analysis

Vitamin E is supplied as d-alpha-tocopheryl succinate, while selenium uses the preferred L-selenomethionine form. Both active amounts are fully disclosed and avoid a proprietary blend.

The 268 mg vitamin E amount is substantial and contributes far more than a basic maintenance serving. Selenium at 200 mcg is also a focused dose, making overlap with multivitamins or antioxidant products important.

One capsule keeps use simple, but the formula is narrow and only moderately priced for two common nutrients. It best suits people intentionally seeking high-dose vitamin E with selenium rather than casual general-health use.

Who is it for
  • Adults specifically seeking vitamin E with selenium
  • People who prefer dry-form vitamin E capsules
Best for
  • Antioxidant nutrient intake
  • Combined vitamin E and selenium supplementation
  • Targeted selenium support

Pros

  • Uses natural-form vitamin E
  • Uses L-selenomethionine
  • Clearly discloses both amounts
  • One-capsule serving

Cons

  • Vitamin E amount is high for routine maintenance
  • Only moderate value
  • Narrow two-nutrient formula

Warnings

  • High-dose vitamin E may increase bleeding risk with warfarin, other anticoagulants, or antiplatelet medicines.
  • Vitamin E should generally be stopped before planned surgery when the surgical team advises because of bleeding concerns.
  • The 200 mcg selenium amount should not be stacked casually with another high-selenium supplement.

Nutrient quality

85 Highest impact

L-selenomethionine is a preferred organic form with clear isomer disclosure. The selenium amount remains below the adult upper limit but requires accounting for other selenium sources.

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Ingredient transparency

83 Highest impact

The selenium amount and source are clearly stated. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

65 High impact

The supplied aggregate rating indicates favorable customer satisfaction. Specific comments are unavailable, so complaint patterns and intended-use fit cannot be verified.

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Value for money

77 High impact

Preferred selenium and natural vitamin E support quality, but the vitamin E amount is aggressive. The serving cost is moderate for the two-active formula.

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Goals

General Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Selenium · 200 mcg

L-selenomethionine supports antioxidant enzymes, thyroid hormone conversion, and immune function, while natural vitamin E adds complementary fat-soluble antioxidant support. Both forms and amounts are clearly disclosed.

The selenium amount is suitable for targeted use but leaves less room for other selenium sources. The high vitamin E amount may increase bleeding risk, especially for people using anticoagulant or antiplatelet medicines.

Study evidence
Selenium Supportive 70 studies
Immunity
Impact
Highest effect
B+ Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Selenium · 200 mcg

Selenium supports antioxidant enzymes and normal immune-cell function, while vitamin E protects cell membranes from oxidative stress. L-selenomethionine and natural vitamin E forms are clearly disclosed.

The selenium amount is substantial, but the vitamin E amount is high for routine immune support. High supplemental vitamin E may increase bleeding risk, especially with anticoagulant or antiplatelet medicines.

Study evidence
Selenium Mixed 37 studies
Vitamin E Supportive 21 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopherol Succinate)
268 mg
Selenium (L-Selenomethionine)
200 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

L-selenomethionine provides a clearly identified, highly bioavailable organic form. The 200 mcg dose matches the common target and maintains a useful safety margin below the daily upper limit. Cost per standardized dose is moderate, with vitamin E adding value to the two-ingredient formula.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium supplementation for the primary prevention of cardiovascular disease.
    Rees K; Hartley L; Day C; Flowers N; Clarke A; Stranges S · The Cochrane database of systematic reviews · 2013
    Meta-analysis19,715 participants12 studies pooledGeneral Health forSelenium
  2. Effect of long-term selenium supplementation on mortality: Results from a multiple-dose, randomised controlled trial.
    Rayman MP; Winther KH; Pastor-Barriuso R; Cold F; Thvilum M; Stranges S; Guallar E; Cold S · Free radical biology & medicine · 2019
    Randomized trial491 participantsGeneral Health forSelenium
  3. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  4. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  5. Selenium intake and multiple health-related outcomes: an umbrella review of meta-analyses.
    Wang P; Chen B; Huang Y; Li J; Cao D; Chen Z; Li J; Ran B; Yang J; Wang R; Wei Q; Dong Q; Liu L · Frontiers in nutrition · 2024
    Systematic reviewGeneral Health forSelenium
  6. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  7. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  8. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  9. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  10. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  11. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  12. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  13. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  14. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  15. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  16. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  17. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  18. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E