DefensePlus
NutriBiotic
DefensePlus
4.9
★ ★ ★ ★ ★
(3938 ratings)
Astragalus 100 mg
Ginger
Maitake Mushroom 50 mg
Score 68.0
DefensePlus is an all-in-one supplement featuring a blend of vitamins, minerals, medicinal mushrooms, and herbal extracts aimed at broad immune support and general wellness. Its comprehensive ingredient list is a strength, though the individual dosages for some botanical components are on the lower side.
Quantity: 45 Tablet(s)Servings size: 1 Tablet(s) (45 servings)
Selected goals:
Other goals:
Immunity
Anti-Aging
Heart Health
Energy
Digestive Health
leaderboard Score 68.0
DefensePlus is an all-in-one supplement featuring a blend of vitamins, minerals, medicinal mushrooms, and herbal extracts aimed at broad immune support and general wellness. Its comprehensive ingredient list is a strength, though the individual dosages for some botanical components are on the lower side.
insights Analysis
DefensePlus by NutriBiotic presents itself as a comprehensive daily supplement targeting a broad spectrum of health goals, primarily focusing on immune support. It combines well-regarded immune-boosting ingredients such as Vitamin C, Zinc, and a blend of traditional herbs and medicinal mushrooms including Astragalus, Echinacea, Reishi, Shiitake, and Maitake. The inclusion of Grapefruit Seed Extract and Ginger Root Extract further contributes to its potential antimicrobial and anti-inflammatory properties. While the blend of ingredients is diverse and generally recognized for their health benefits, the individual dosages for many of the herbal and mushroom extracts are relatively modest when compared to stand-alone supplements or clinical study levels, suggesting that the product aims for broad rather than intensive support.
- Contains a wide array of well-known immune-supportive ingredients like Vitamin C, Zinc, Echinacea, Astragalus, and various medicinal mushrooms, offering a synergistic approach.
- The inclusion of ingredients like Ginger and Grapefruit Seed Extract provides additional benefits for digestive and general wellness, expanding beyond just immunity.
- At $0.29 per serving, it offers an economical way to get a blend of these ingredients daily.
- Many herbal and mushroom extracts are present in relatively low quantities (e.g., 50-100mg), which might not be sufficient to achieve the full therapeutic effects seen in studies for some of the stated goals.
- The product claims to support a very wide range of goals (Mood, Testosterone, Metabolism, Weight Loss, Energy) for which the ingredients and their dosages provide minimal to no direct evidence or significant impact.
- For several herbal extracts, the 'Form' is listed as 'N/A', implying a lack of standardization to active compounds, which can lead to variable potency.
- Individuals with autoimmune conditions should exercise caution or consult a healthcare professional due to the immune-modulating effects of ingredients like Astragalus, Echinacea, and medicinal mushrooms, which could potentially stimulate the immune system.
- The product contains a wide array of botanicals, increasing the potential for individual sensitivities or interactions with other medications, particularly for those on chronic prescriptions.
$12.17($0.27 per serving)
 iHerb | $ 12.17 | |
 Amazon | $ 13.49 |
bolt Effectiveness for goals
Vitamin C and Zinc are essential nutrients that play a key role in normal immune function and antioxidant processes. Mushroom extracts, such as Shiitake, Maitake, and Reishi, contain compounds like beta-glucans which are recognized for their potential to support immune cell activity. Together, these ingredients may help maintain overall immune system health.
Echinacea is often recognized for its traditional use in supporting immune responses, particularly during seasonal changes. Astragalus is considered an adaptogen and is traditionally used to support the body's natural defenses and overall vitality. When combined, these herbs may offer synergistic support for immune system maintenance.
Zinc is an essential trace mineral vital for the development and function of immune cells. It contributes to the integrity of immune defenses and plays a role in antioxidant processes within the body. Adequate zinc levels are important for maintaining a healthy immune response.
Vitamin C is an antioxidant that helps protect cells from damage caused by free radicals. It is essential for the normal function of various immune cells and supports the body's natural defense mechanisms. Additionally, Vitamin C is involved in collagen formation, which is important for healthy skin, blood vessels, bones, and cartilage.
Shiitake, Maitake, and Reishi mushrooms are all recognized for their rich content of polysaccharides, particularly beta-glucans. These compounds are studied for their potential to modulate the immune system by interacting with immune cells. Combining these extracts may offer a broader spectrum of immune support compared to using a single type.
schedule Dosage, timing & forms
Grapefruit seed extract, like grapefruit, can interact with certain medications by influencing drug metabolism. It is important to consult a healthcare professional regarding potential interactions before combining this supplement with any prescription drugs. Taking them separately may not always prevent interactions.
While consistency is key, many individuals prefer to take such supplements with food to support absorption and reduce potential stomach upset. Following the product's specific instructions, often with a meal, can be beneficial for consistent intake.
Zinc and Vitamin C are often better tolerated and absorbed when consumed with food. Ginger can also be taken with food to help prevent potential digestive discomfort. Always refer to the product label for specific guidance.
For sustained support, supplements combining these ingredients are commonly taken once or twice daily. Adhering to the specific serving size and frequency indicated on the product label is essential for intended use. Regular intake as directed contributes to the product's efficacy.
Tablets provide a precise and stable dose of botanical ingredients. They should typically be swallowed whole with water, as directed, and not chewed or crushed unless explicitly stated. This ensures proper delivery and absorption of the active compounds.
health_and_safety Safety & interactions
Due to the presence of certain herbal extracts like Yarrow and Oregon Grape, this combination of ingredients is generally not recommended for use during pregnancy or breastfeeding. It is important to consult a healthcare professional before use if you are pregnant or nursing.
Several ingredients, including ginger, shiitake, maitake, reishi, yarrow, astragalus, and Oregon grape, may possess properties that could affect blood clotting. Therefore, using this blend with anticoagulant or antiplatelet medications should be discussed with a healthcare provider.
Echinacea and Astragalus are known to influence immune system activity, which could theoretically interfere with the effectiveness of immunosuppressant drugs. Individuals taking such medications should consult their doctor before using supplements containing these herbs.
Herbs such as Maitake, Ginger, Reishi, Astragalus, and Oregon Grape may influence blood sugar or blood pressure levels. If you are taking medication for diabetes or hypertension, it is advisable to consult a healthcare professional before using this supplement.
Grapefruit seed extract (GSE) is distinct from grapefruit juice. While grapefruit juice is known to interact with numerous medications by affecting certain liver enzymes, the same level of interaction has not been consistently demonstrated for pure grapefruit seed extract. However, due to potential variability in products and common consumer concern, it's prudent to consult a healthcare provider if you have concerns about medication interactions.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin C | 125 mg |
Zinc | 5 mg |
Grapefruit seed extract | 250 mg |
Astragalus | 100 mg |
Reishi Mushroom Extract | 100 mg |
Echinacea angustifolia extract | 50 mg |
Ginger root extract | 50 mg |
Maitake Mushroom Extract | 50 mg |
Oregon grape | 50 mg |
Shiitake Extract | 50 mg |
Yarrow extract | 50 mg |
Categories
Ginger 50.0
The product contains 50mg of Ginger root extract. While ginger is a valuable ingredient for its digestive and anti-inflammatory properties, this dosage is on the lower end for significant effects, especially when compared to alternative products offering 200mg-1000mg or more of ginger.
Maitake Mushroom 45.0
The 50mg of Maitake Mushroom Extract is a modest dose. While Maitake is a beneficial immune mushroom, many specialized mushroom supplements or blends feature higher concentrations (e.g., 100-200mg or more) for more pronounced effects in this category.
Astragalus 40.0
With 100mg of Astragalus, the dosage is considerably lower than many dedicated Astragalus supplements, which often provide 500mg or more for immune benefits. While it contributes to the overall immune blend, its individual impact for this collection category is limited by the quantity.
Goals
Immunity 75.0
This is the product's primary strength, featuring a solid combination of Vitamin C (125mg), Zinc (5mg), and a range of immune-modulating herbs and mushrooms like Astragalus (100mg), Echinacea (50mg), Reishi (100mg), Shiitake (50mg), and Maitake (50mg). While some herbal dosages are moderate, the synergistic effect of multiple known immune supporters provides a good foundation for daily immune maintenance compared to single-ingredient alternatives.
Ginger (50mg) and the various mushroom extracts (Reishi, Shiitake, Maitake) possess known anti-inflammatory properties. Vitamin C also contributes as an antioxidant. However, the dosages of these ingredients are modest for robust anti-inflammatory effects compared to specialized anti-inflammatory supplements.
Digestive Health 40.0
Ginger root extract (50mg) and Grapefruit Seed Extract (250mg) offer some general digestive support due to their carminative and antimicrobial properties. However, these dosages are relatively low for significant therapeutic impact on specific digestive issues, and the product lacks common gut-specific ingredients like probiotics or digestive enzymes.
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