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Melatonin 2.5 mg Orange Flavor

Source Naturals Sleep Science
4.6
★ ★ ★ ★ ★
(353 ratings)
Melatonin 2.5 mg
Product Image
Score85
A well-dosed orange dissolving melatonin option with a small amount of active-form B6. Strong serving value is offset by the lack of overnight release.
How scoring works
Quantity:240 Liquid(s) • (240 servings)
Goals:
Sleep Support

Score 85

A well-dosed orange dissolving melatonin option with a small amount of active-form B6. Strong serving value is offset by the lack of overnight release.
How scoring works

Also available as

1 option
Peppermint Melatonin 2.5 mg • 240 Liquid(s) • 240 servings $22.75 ($0.09 per serving)
$22.75($0.09 per serving)
iHerb
$ 22.75
iHerb
$ 22.75
Vitacost
$ 22.75
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Analysis

A 2.5 mg melatonin amount provides a measured middle ground between very low and high-dose products. Orange-flavored dissolving delivery may support relatively prompt bedtime use.

Coenzymated vitamin B6 and pyridoxal 5-phosphate are both listed at small amounts. They add little to the main sleep pathway but are transparently quantified.

The 240-serving supply supports extended use and strong practical value. Lack of sustained release makes the product a better fit for falling asleep than repeated waking.

Who is it for
  • Adults seeking 2.5 mg melatonin
  • Users who prefer orange flavor
  • People wanting a large supply
Best for
  • Sleep-onset support
  • Dissolving bedtime use
  • Long-term serving value

Pros

  • Practical 2.5 mg amount
  • Active-form vitamin B6 is disclosed
  • 240 servings

Cons

  • No sustained-release feature
  • Vitamin B6 adds limited sleep value
  • Flavored format may not suit everyone

Warnings

  • Melatonin may cause next-day drowsiness or vivid dreams
  • Avoid driving if morning alertness is reduced

Nutrient quality

92 Highest impact

The 2.5 mg amount is well aligned with gentle sleep support. The dissolving format may support quicker onset but not overnight release.

.

Ingredient transparency

84 Highest impact

Active amounts are clear without a hidden blend. Complete directions and inactive ingredients remain unavailable.

.

Customer satisfaction

68 High impact

The supplied average is strong and supported by substantial volume. No review themes were provided, so consistency and purpose-specific experience cannot be assessed.

.

Value for money

93 Highest impact

A very low serving cost and clearly stated dose support value. Missing release tailoring and purity verification limit differentiation.

.
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Goals

Sleep Support
Sleep Support
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB- CoverageA Formula Quality
Melatonin · 2.5 mg

The dissolving lozenge supplies a well-targeted melatonin amount for circadian timing and sleep onset. A small amount of active-form vitamin B6 accompanies it, while the mouth-dissolving format may support relatively quick use.

No sustained-release feature is disclosed, so the product is less suited to repeated nighttime awakenings. Melatonin can cause drowsiness or vivid dreams, and users should avoid alertness-dependent tasks if grogginess persists.

Study evidence
Melatonin Supportive 181 studies
Vitamin B6 Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin B-6 (Coenzymated, Pyridoxal 5-Phosphate)
 335 mcg
Melatonin
2.5 mg
Adults 18–50 Women
Report overview
Melatonin · 2.5 mg OverallScore73
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The low melatonin dose aligns with the preferred range and comes in a liquid-classified lozenge format suited to rapid use. The formula is immediate release, so it is aimed more at sleep onset than overnight maintenance. Its serving cost is efficient, although no independent purity certification is disclosed.

View ingredientView products
Loading alternative details
88 Performance

Melatonin 1.0 mg Orange Flavor

Source Naturals Sleep Science
<p>Its label clearly provides 1 mg of Melatonin, making it a more clearly defined melatonin option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
87 Performance

Melatonin Lozenges 3 mg

Life Extension
<p>Its label clearly provides 3 mg of Melatonin, making it a more clearly defined melatonin option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
86 Performance

Melatonin 1 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>Its label clearly provides 1 mg of Melatonin, making it a more clearly defined melatonin option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
88 Budget

Melatonin 1.0 mg Peppermint Flavor

Source Naturals Sleep Science
<p>Its label clearly provides 1 mg of Melatonin, preserving relevant melatonin coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
86 Budget

Melatonin 3 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>Its label clearly provides 3 mg of Melatonin, preserving relevant melatonin coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
83 Budget

Melatonin 3 mg

NOW
<p>Its label clearly provides 3 mg of Vitamin B6 as Pyridoxine Hydrochloride, preserving relevant melatonin coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
86 Value

Melatonin Lozenge 2.5 mg

Nature's Way
<p>Its label clearly provides 2.50 mg of Melatonin, keeping the formula relevant to melatonin. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
86 Value

Fast-Dissolve Melatonin 3 mg Artificial Strawberry Flavor

Spring Valley
<p>Its label clearly provides 3 mg of Melatonin, keeping the formula relevant to melatonin. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
85 Value

Liquid Melatonin

NOW
<p>Its label clearly provides 3 mg of Melatonin, keeping the formula relevant to melatonin. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  4. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  5. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  6. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  7. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  8. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  9. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  10. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  11. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6