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Selenium Synergy

Jarrow Formulas
4.8
★ ★ ★ ★ ★
(3343 ratings)
Selenium 200 mcg
Product Image
Score84
A transparent selenium, vitamin E, riboflavin, and glucoraphanin blend with a sensible antioxidant focus.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Immunity
General Health

Score 84

A transparent selenium, vitamin E, riboflavin, and glucoraphanin blend with a sensible antioxidant focus.
How scoring works
$10.17($0.16 per serving)
iHerb
$ 10.17
Vitacost
$ 13.12
Daily Vita
$ 12.99
Pure Formulas
$ 13.12
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Analysis

The capsule supplies 200 mcg selenium as methylselenocysteine with vitamin E and riboflavin. These clearly named nutrients provide a transparent antioxidant-support base.

Ten milligrams of glucoraphanin adds a cruciferous-plant compound, but no myrosinase is listed. Conversion to downstream compounds can therefore vary with diet and gut activity.

The formula offers more breadth than a single selenium capsule without becoming overly complex. It fits people who specifically want selenium paired with tocopherol and cruciferous support.

Who is it for
  • Adults wanting more than a single selenium ingredient
  • People seeking a cruciferous-compound add-on
Best for
  • Antioxidant nutrient combinations
  • Selenium plus glucoraphanin

Pros

  • Uses methylselenocysteine
  • Includes natural-form vitamin E
  • Clearly doses glucoraphanin

Cons

  • No myrosinase is listed
  • Not a broad multivitamin
  • Non-active ingredients are unavailable

Warnings

  • Count the 200 mcg selenium amount with other supplements to avoid excessive combined intake.

Nutrient quality

92 Highest impact

Well-chosen selenium and vitamin E forms anchor a coherent antioxidant formula. Useful supporting nutrients add depth without creating an obvious dosing or filler concern.

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Ingredient transparency

83 Highest impact

Active amounts and key forms are clearly disclosed without a hidden blend. Explicit directions and non-active capsule ingredients are absent from the supplied data.

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Customer satisfaction

71 High impact

The available rating is strong and the sample is large. Detailed feedback was not supplied, so repeated complaints and alignment with the intended use remain uncertain.

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Value for money

87 Highest impact

Useful forms and relevant supporting nutrients provide solid value. The broader formula costs more than a single-mineral option but delivers meaningful added depth.

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Goals

Immunity
Immunity
Impact
Highest effect
A- Goal FitA Strength of SupportB CoverageA Formula Quality
Selenium · 200 mcg

A well-defined selenium form is paired with vitamin E, riboflavin, and glucoraphanin for focused antioxidant and metabolic support. All active amounts are clear, and the selenium dose is substantial.

The formula is coherent without trying to cover every nutritional pathway. People already taking selenium should include the 200 mcg serving when checking their total long-term intake.

Study evidence
Selenium Mixed 37 studies
Vitamin E Supportive 21 studies
General Health
General Health
Impact
Highest effect
A- Goal FitA Strength of SupportB- CoverageA- Formula Quality
Selenium · 200 mcg

Methylselenocysteine provides an absorbable organic selenium form at 200 mcg. Selenium supports antioxidant enzymes and thyroid hormone metabolism, while vitamin E and riboflavin add complementary nutrient support.

The amount is substantial and remains below the adult upper intake limit, but long-term use should account for dietary selenium and other supplements. Glucoraphanin adds a related antioxidant-pathway ingredient, although the supplied data do not establish its active conversion.

Study evidence
Selenium Supportive 70 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopheryl Succinate)
 20 mg
Riboflavin (Vitamin B2)
 2 mg
Selenium (Methylselenocysteine)
 200 mcg
Glucoraphanin
10 mg
Adults 18–50
Report overview
Selenium (Methylselenocysteine) · 200 mcg OverallScore91
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Methylselenocysteine provides an organic selenium form with good absorption potential. The serving supplies a well-supported amount while retaining a useful safety margin for dietary intake. Its cost per standard selenium dose offers solid value, and the added nutrients broaden the formula.

View ingredientView products
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87 Performance

Selenium 200 mcg

Nature's Way
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, making it a more clearly defined selenium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
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Selenium 200 mcg

California Gold Nutrition
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, making it a more clearly defined selenium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
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Selenium 200 mcg

NOW
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, making it a more clearly defined selenium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
87 Budget

Se-Methyl L-Selenocysteine 200 mcg

Life Extension
<p>Its label clearly provides 200 mcg of Selenium as Se-Methyl L-Selenocysteine, preserving relevant selenium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
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Selenium 200 mcg

Solgar
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, preserving relevant selenium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
86 Budget

SeMSC Selenium 200 mcg

Swanson
<p>Its label clearly provides 200 mcg of Selenium as L-Se-Methylselenocysteine, preserving relevant selenium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
87 Value

Selenium 200 mcg

Source Naturals
<p>Its label clearly provides 37 mg of Calcium as Dibasic Calcium Phosphate, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
87 Value

Selenium 200 mcg

NOW
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
86 Value

Selenium 200 mcg

Solgar
<p>Its label clearly provides 200 mcg of Selenium as L-Selenomethionine, keeping the formula relevant to selenium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium supplementation for the primary prevention of cardiovascular disease.
    Rees K; Hartley L; Day C; Flowers N; Clarke A; Stranges S · The Cochrane database of systematic reviews · 2013
    Meta-analysis19,715 participants12 studies pooledGeneral Health forSelenium
  2. Effect of long-term selenium supplementation on mortality: Results from a multiple-dose, randomised controlled trial.
    Rayman MP; Winther KH; Pastor-Barriuso R; Cold F; Thvilum M; Stranges S; Guallar E; Cold S · Free radical biology & medicine · 2019
    Randomized trial491 participantsGeneral Health forSelenium
  3. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  4. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  5. Selenium intake and multiple health-related outcomes: an umbrella review of meta-analyses.
    Wang P; Chen B; Huang Y; Li J; Cao D; Chen Z; Li J; Ran B; Yang J; Wang R; Wei Q; Dong Q; Liu L · Frontiers in nutrition · 2024
    Systematic reviewGeneral Health forSelenium
  6. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  7. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  8. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  9. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  10. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  11. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  12. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  13. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  14. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  15. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  16. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  17. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  18. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E